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How to get fromIllinois to Greenvilleby plane, bus (Greyhound, Flixbus), train, bus, car, taxi, or bus (Flixbus, Greyhound)

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There are 7 ways to get from Illinois to Greenville by plane, bus (Greyhound, Flixbus), train, bus, car, taxi, or bus (Flixbus, Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Chicago O'Hare International Airport to Greenville–Spartanburg International Airport

    best
    1. Fly from Chicago O'Hare International Airport (ORD) to Greenville–Spartanburg International Airport (GSP)plane plane ORD - GSP
    4h 3m
    $132–600

  2. Drive 667.5 mi

    cheapest
    1. Drive from Chicago to Greenvillecar car 667.5 mi
    12h 43m
    $122–176

  3. Bus

    1. Take the bus from Chicago Bus Station to Atlanta Bus Stationbus bus Greyhound US0100
    2. Take the bus from Atlanta to Taqueria Guadalajara - Greenvillebus bus Charlotte
    21h 20m
    $172–377

  4. Train, bus

    1. Take the train from Chicago Union Station to Carytrain train
    2. Take the train from Cary to Charlotte Amtrak Stationtrain train
    3. Take the bus from Charlotte to Taqueria Guadalajara - Greenvillebus bus
    32h 28m
    $450–980

  5. Fly Chicago O'Hare International Airport to Asheville Regional Airport, taxi

    1. Fly from Chicago O'Hare International Airport (ORD) to Asheville Regional Airport (AVL)plane plane ORD - AVL
    2. Take the taxi from Asheville-Airport-AVL to Greenvilletaxi taxi
    4h 39m
    $202–515

  6. Fly Chicago Midway International Airport to Asheville Regional Airport, taxi

    1. Fly from Chicago Midway International Airport (MDW) to Asheville Regional Airport (AVL)plane plane MDW - AVL
    2. Take the taxi from Asheville-Airport-AVL to Greenvilletaxi taxi
    6h 21m
    $238–665

  7. Bus via Chicago

    1. Take the bus from Chicago to Atlanta Bus Stationbus bus FlixBus 2512
    2. Take the bus from Atlanta to Taqueria Guadalajara - Greenvillebus bus Charlotte
    21h 49m
    $176–387

Chicago O'Hare International Airport (ORD) to Greenville–Spartanburg International Airport (GSP) flights

Calendar98Weekly Planes
Duration3h 7mAverage Duration
Ticket$96Cheapest Price
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Questions & Answers

Map of how to get from Illinois to Greenville.ExpandLaunch map view
  • Distance: 608.1 mi
  • Duration: 4h 3m

What companies run services between Illinois, USA and Greenville, SC, USA?

American Airlines, United Airlines, and Delta fly from Chicago O'Hare International Airport (ORD) to Greenville–Spartanburg International Airport (GSP) hourly. Alternatively, you can take a bus from Chicago Bus Station to Greenville via Atlanta Bus Station, Garnett Station, Doraville Station, Atlanta, and Taqueria Guadalajara - Greenville in around 21h 20m.

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