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How to get fromIllinois to Louisvilleby bus (Greyhound, Amtrak), train, bus, car, subway, plane, or bus (Amtrak)

Find Transport to Louisville

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There are 7 ways to get from Illinois to Louisville by bus (Greyhound, Amtrak), train, bus, car, subway, plane, or bus (Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus via Indianapolis

    best
    1. Take the bus from Chicago Bus Station to Indianapolis Union Stationbus bus Greyhound US0100 / ...
    2. Take the bus from Indianapolis Union Station to Louisville, KYbus bus Chicago
    6h
    $54–91

  2. Bus (Amtrak)

    cheapest
    1. Take the bus from Chicago Union Station to Louisville, KYbus bus Chicago
    6h 45m
    $50–60

  3. Train, bus (Amtrak)

    1. Take the train from Chicago Union Station to Indianapolistrain train Cardinal
    2. Take the bus from Indianapolis Union Station to Louisville, KYbus bus Chicago
    7h 49m
    $130–211

  4. Drive  293.6 mi

    1. Drive from Chicago to Louisvillecar car 293.6 mi
    5h 4m
    $54–78

  5. Subway to Chicago Midway International Airport, fly to Louisville International Airport

    1. Take the subway from Adams/Wabash to Midwaysubway subway
    2. Fly from Chicago Midway International Airport (MDW) to Louisville International Airport (SDF)plane plane MDW - SDF
    3h 56m
    $98–658

  6. Fly Chicago O'Hare International Airport to Louisville International Airport

    1. Fly from Chicago O'Hare International Airport (ORD) to Louisville International Airport (SDF)plane plane ORD - SDF
    4h 27m
    $74–468

  7. Fly Chicago O'Hare International Airport to Blue Grass Airport, drive

    1. Fly from Chicago O'Hare International Airport (ORD) to Blue Grass Airport (LEX)plane plane ORD - LEX
    2. Drive from Lexington-Airport-LEX to Louisvillecar car
    4h 38m
    $56–304

Illinois to Louisville by bus

Calendar14Weekly Buses
Duration6hAverage Duration
Ticket$54Cheapest Price
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Comparing Your Travel Options

Map of how to get from Illinois to Louisville.ExpandLaunch map view
  • Distance: 294.8 mi
  • Duration: 6h

What companies run services between Illinois, USA and Louisville, KY, USA?

You can take a bus from Chicago Bus Station to Louisville, KY via Indianapolis Union Station in around 6h. Alternatively, American Airlines and United Airlines fly from Chicago O'Hare International Airport (ORD) to Louisville International Airport (SDF) every 3 hours.

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