There are 6 ways to get from Illinois to Missouri by plane, train (Amtrak), bus (Greyhound), car, or subway
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Chicago O'Hare International Airport to Lambert–St. Louis International Airport
best- Fly from Chicago O'Hare International Airport (ORD) to Lambert–St. Louis International Airport (STL)plane ORD - STL
3h 43m$276–708Subway to Chicago Midway International Airport, fly to Lambert–St. Louis International Airport
cheapest- Take the subway from Adams/Wabash to Midwaysubway
- Fly from Chicago Midway International Airport (MDW) to Lambert–St. Louis International Airport (STL)plane MDW - STL
3h 27m$86–558Train (Amtrak)
- Take the train from Chicago Union Station to Kansas Citytrain Southwest Chief / ...
7h 35m$140–290Bus
- Take the bus from Chicago Bus Station to Des Moinesbus Greyhound US0123S / ...
- Take the bus from Des Moines to Kansas Citybus Jefferson 803 / ...
11h$102–171Drive 506.6 mi
- Drive from Chicago to Kansas Citycar 506.6 mi
8h 37m$93–134Fly Chicago O'Hare International Airport to Columbia Regional Airport
- Fly from Chicago O'Hare International Airport (ORD) to Columbia Regional Airport (COU)plane ORD - COU
3h 30m$98–370
Illinois to Missouri by train and tram (Amtrak)
Questions & Answers
The cheapest way to get from Illinois to Missouri is to drive which costs $90 - $140 and takes 8h 37m.
The fastest way to get from Illinois to Missouri is to subway and fly which takes 3h 27m and costs $85 - $600.
No, there is no direct bus from Illinois station to Missouri. However, there are services departing from Chicago Bus Station and arriving at Kansas City via Des Moines. The journey, including transfers, takes approximately 11h.
No, there is no direct train from Illinois station to Missouri. However, there are services departing from Chicago Union Station and arriving at Metro Center via Union Station. The journey, including transfers, takes approximately 7h 35m.
The distance between Illinois and Missouri is 292 miles. The road distance is 509.6 miles.
The best way to get from Illinois to Missouri without a car is to train which takes 7h 35m and costs $140 - $290.
It takes approximately 3h 43m to get from Illinois to Missouri, including transfers.
Illinois to Missouri bus services, operated by Greyhound USA, depart from Chicago Bus Station.
Illinois to Missouri train services, operated by Amtrak, depart from Chicago Union Station.
The best way to get from Illinois to Missouri is to fly which takes 3h 43m and costs $270 - $750. Alternatively, you can train, which costs $140 - $290 and takes 7h 35m, you could also bus, which costs $100 - $180 and takes 11h.
What companies run services between Illinois, USA and Missouri, USA?
American Airlines, GoJet Airlines, and United Airlines fly from Chicago O'Hare International Airport (ORD) to Lambert–St. Louis International Airport (STL) hourly. Alternatively, Amtrak operates a train from Chicago Union Station to Kansas City twice daily. Tickets cost $140–290 and the journey takes 7h 23m.
- Website
- united.com
Flights from Chicago O'Hare International Airport to Lambert–St. Louis International Airport
- Ave. Duration
- 1h 30m
- When
- Every day
- Estimated price
- $65–430
Flights from Chicago O'Hare International Airport to Columbia Regional Airport
- Ave. Duration
- 1h 35m
- When
- Every day
- Estimated price
- $45–300
- Website
- southwest.com
Flights from Chicago Midway International Airport to Lambert–St. Louis International Airport
- Ave. Duration
- 1h 11m
- When
- Every day
- Estimated price
- $80–550
- Website
- aa.com
Flights from Chicago O'Hare International Airport to Lambert–St. Louis International Airport
- Ave. Duration
- 1h 23m
- When
- Every day
- Estimated price
- $65–430
Flights from Chicago O'Hare International Airport to Columbia Regional Airport
- Ave. Duration
- 1h 28m
- When
- Every day
- Estimated price
- $45–300
- Website
- gojetairlines.com
Flights from Chicago O'Hare International Airport to Lambert–St. Louis International Airport
- Ave. Duration
- 1h 28m
- When
- Every day
- Estimated price
- $65–430
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Chicago Union Station to Kansas City
- Ave. Duration
- 7h 23m
- Frequency
- Twice daily
- Estimated price
- $140–290
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 888-968-7282
- Website
- transitchicago.com
Subway from Adams/Wabash to Midway
- Ave. Duration
- 23 min
- Frequency
- Every 15 minutes
- Estimated price
- $2–5
- Website
- https://www.transitchicago.com
- Schedules at
- https://www.transitchicago.com/schedules/
- Adult
- $2–5
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- greyhound.com
Bus from Chicago Bus Station to Des Moines
- Ave. Duration
- 6h 30m
- Frequency
- 3 times a day
- Estimated price
- $50–100
- Website
- https://www.greyhound.com/
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from Des Moines to Kansas City
- Ave. Duration
- 3h 30m
- Frequency
- Twice daily
- Estimated price
- $50–75
- Book at
- https://www.jeffersonlines.com
- Adult
- $50–75
Want to know more about travelling around United States
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More Questions & Answers
Illinois to Missouri bus services, operated by Greyhound USA, arrive at Des Moines station.
Illinois to Missouri train services, operated by Amtrak, arrive at Kansas City station.
Yes, the driving distance between Illinois to Missouri is 510 miles. It takes approximately 8h 37m to drive from Illinois to Missouri.
There are 515+ hotels available in Missouri.