There are 6 ways to get from Illinois to Missouri by subway, plane, train (Amtrak), bus (Greyhound), or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Subway to Chicago Midway International Airport, fly to Lambert–St. Louis International Airport
best- Take the subway from Adams/Wabash to Midwaysubway
- Fly from Chicago Midway International Airport (MDW) to Lambert–St. Louis International Airport (STL)plane MDW - STL
3h 27m$76–508Bus (Greyhound)
cheapest- Take the bus from Chicago Bus Station to Des Moinesbus Greyhound US0123S / ...
- Take the bus from Des Moines to Kansas City Bus Stationbus Greyhound US0156
10h 45m$74–144Train (Amtrak)
- Take the train from Chicago Union Station to Kansas Citytrain Southwest Chief / ...
7h 35m$110–260Drive 506.6 mi
- Drive from Chicago to Kansas Citycar 506.6 mi
8h 37m$93–134Fly Chicago O'Hare International Airport to Columbia Regional Airport
- Fly from Chicago O'Hare International Airport (ORD) to Columbia Regional Airport (COU)plane ORD - COU
3h 31m$92–360Fly Chicago O'Hare International Airport to Lambert–St. Louis International Airport
- Fly from Chicago O'Hare International Airport (ORD) to Lambert–St. Louis International Airport (STL)plane ORD - STL
3h 51m$326–708
Illinois to Missouri by train and tram (Amtrak)
Questions & Answers
The cheapest way to get from Illinois to Missouri is to bus which costs $70 - $150 and takes 10h 45m.
The fastest way to get from Illinois to Missouri is to subway and fly which takes 3h 27m and costs $75 - $550.
No, there is no direct bus from Illinois station to Missouri station. However, there are services departing from Chicago Bus Station and arriving at Kansas City Bus Station via Des Moines. The journey, including transfers, takes approximately 10h 45m.
No, there is no direct train from Illinois station to Missouri. However, there are services departing from Chicago Union Station and arriving at Metro Center via Union Station. The journey, including transfers, takes approximately 7h 35m.
The distance between Illinois and Missouri is 278 miles. The road distance is 509.6 miles.
The best way to get from Illinois to Missouri without a car is to train which takes 7h 35m and costs $110 - $260.
It takes approximately 3h 27m to get from Illinois to Missouri, including transfers.
Illinois to Missouri bus services, operated by Greyhound USA, depart from Chicago Bus Station.
Illinois to Missouri train services, operated by Amtrak, depart from Chicago Union Station.
The best way to get from Illinois to Missouri is to train which takes 7h 35m and costs $110 - $260. Alternatively, you can bus, which costs $70 - $150 and takes 10h 45m, you could also fly, which costs $90 - $360 and takes 3h 31m.
What companies run services between Illinois, USA and Missouri, USA?
Amtrak operates a train from Chicago Union Station to Kansas City twice daily. Tickets cost $110–260 and the journey takes 7h 23m. Alternatively, you can take a bus from Chicago Bus Station to Kansas City Bus Station via Des Moines in around 10h 45m.
- Website
- united.com
Flights from Chicago O'Hare International Airport to Columbia Regional Airport
- Ave. Duration
- 1h 35m
- When
- Every day
- Estimated price
- $40–290
Flights from Chicago O'Hare International Airport to Lambert–St. Louis International Airport
- Ave. Duration
- 1h 30m
- When
- Every day
- Estimated price
- $50–370
- Phone
- +1 888-968-7282
- Website
- Chicago Transit Authority
Subway from Adams/Wabash to Midway
- Ave. Duration
- 23 min
- Frequency
- Every 15 minutes
- Estimated price
- $2–5
- Website
- Chicago Transit Authority
- Schedules at
- Chicago Transit Authority Schedules & Routes
- Adult
- $2–5
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Chicago Bus Station to Des Moines
- Ave. Duration
- 6h 30m
- Frequency
- 3 times a day
- Estimated price
- $45–90
- Website
- Greyhound
Bus from Des Moines to Kansas City Bus Station
- Ave. Duration
- 3h 15m
- Frequency
- Once daily
- Estimated price
- $27–55
- Website
- Greyhound
Want to know more about travelling around United States
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More Questions & Answers
Illinois to Missouri bus services, operated by Greyhound USA, arrive at Des Moines station.
Illinois to Missouri train services, operated by Amtrak, arrive at Kansas City station.
Yes, the driving distance between Illinois to Missouri is 510 miles. It takes approximately 8h 37m to drive from Illinois to Missouri.
Book your Illinois to Missouri bus tickets online with Omio and FlixBus.
There are 505+ hotels available in Missouri.