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How to get fromIllinois to Saint Charlesby train (Amtrak), bus (Flixbus), car, plane, bus, or subway

Find Transport to Saint Charles

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There are 5 ways to get from Illinois to Saint Charles by train (Amtrak), bus (Flixbus), car, plane, bus, or subway

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train (Amtrak)

    best
    1. Take the train from Chicago Union Station to St. Louistrain train Lincoln Service / ...
    6h 11m
    $95–187

  2. Bus

    cheapest
    1. Take the bus from Chicago Bus Station to St Louis Bus Stationbus bus FlixBus 2510 / ...
    7h 53m
    $54–86

  3. Drive 309.5 mi

    1. Drive from Chicago to Saint Charlescar car 309.5 mi
    5h 15m
    $57–82

  4. Fly from Chicago O'Hare International Airport, line 34 bus

    1. Fly from Chicago O'Hare International Airport (ORD) to Lambert–St. Louis International Airport (STL)plane plane ORD - STL
    2. Take the bus from North Hanley Transit Center to 4375 Rider Trail North Sbbus bus
    4h 7m
    $276–709

  5. Subway to Chicago Midway International Airport, fly, line 34 bus

    1. Take the subway from Adams/Wabash to Midwaysubway subway
    2. Fly from Chicago Midway International Airport (MDW) to Lambert–St. Louis International Airport (STL)plane plane MDW - STL
    3. Take the bus from North Hanley Transit Center to 4375 Rider Trail North Sbbus bus
    3h 52m
    $86–559

Illinois to Saint Charles by train and bus (Amtrak)

Calendar38Weekly Services
Duration6h 11mAverage Duration
Ticket$95Cheapest Price
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Questions & Answers

Map of how to get from Illinois to Saint Charles.ExpandLaunch map view
  • Distance: 302.1 mi
  • Duration: 6h 11m

What companies run services between Illinois, USA and Saint Charles, MO, USA?

Amtrak operates a train from Chicago Union Station to St. Louis 5 times a day. Tickets cost $90–190 and the journey takes 4h 46m. Alternatively, Jefferson Lines operates a bus from Chicago Bus Station to St Louis Bus Station 3 times a day. Tickets cost $75–110 and the journey takes 5h 55m. Flixbus USA also services this route twice daily.

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