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How to get fromIllinois to Saint Charlesby train (Amtrak), bus (Flixbus), car, subway, plane, bus, or taxi

Find Transport to Saint Charles

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There are 5 ways to get from Illinois to Saint Charles by train (Amtrak), bus (Flixbus), car, subway, plane, bus, or taxi

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train (Amtrak)

    best
    1. Take the train from Chicago Union Station to St. Louistrain train Lincoln Service / ...
    6h 20m
    $89–188

  2. Drive  309.5 mi

    cheapest
    1. Drive from Chicago to Saint Charlescar car 309.5 mi
    5h 15m
    $57–82

  3. Bus (Flixbus)

    1. Take the bus from Chicago Bus Station to St Louis Bus Stationbus bus FlixBus 2510 / ...
    8h 2m
    $65–92

  4. Subway to Chicago Midway International Airport, fly, line 34 bus, taxi

    1. Take the subway from Adams/Wabash to Midwaysubway subway
    2. Fly from Chicago Midway International Airport (MDW) to Lambert–St. Louis International Airport (STL)plane plane MDW - STL
    3. Take the bus from North Hanley Transit Center to 4375 Rider Trail North Sbbus bus
    4. Take the taxi from 4375 Rider Trail North Sb to Saint Charlestaxi taxi
    4h 1m
    $98–579

  5. Fly from Chicago O'Hare International Airport, line 34 bus, taxi

    1. Fly from Chicago O'Hare International Airport (ORD) to Lambert–St. Louis International Airport (STL)plane plane ORD - STL
    2. Take the bus from North Hanley Transit Center to 4375 Rider Trail North Sbbus bus
    3. Take the taxi from 4375 Rider Trail North Sb to Saint Charlestaxi taxi
    4h 22m
    $342–729

Chicago Midway International Airport (MDW) to Lambert–St. Louis International Airport (STL) flights

Calendar32Weekly Planes
Duration1h 11mAverage Duration
Ticket$75Cheapest Price
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Comparing Your Travel Options

Map of how to get from Illinois to Saint Charles.ExpandLaunch map view
  • Distance: 307.8 mi
  • Duration: 6h 20m

What companies run services between Illinois, USA and Saint Charles, MO, USA?

Amtrak operates a train from Chicago Union Station to St. Louis 5 times a day. Tickets cost $65–170 and the journey takes 4h 46m. Alternatively, Flixbus USA operates a bus from Chicago Bus Station to St Louis Bus Station twice daily. Tickets cost $45–70 and the journey takes 5h 55m.

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