There are 7 ways to get from Independence to St. Louis by bus (Greyhound), taxi, bus, train, car, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus
best- Take the bus from Coffeyville to Kansas Citybus Jefferson 802 / ...
- Take the bus from Kansas City Bus Station to St Louis Bus Stationbus Greyhound US0136 / ...
9h 3m$88–154Drive 352.3 mi
cheapest- Drive from Independence to St. Louiscar 352.3 mi
6h 14m$65–93Taxi, bus, train
- Take the taxi from Independence to Chanutetaxi
- Take the bus from Chanute to Kansas Citybus
- Take the train from Kansas City to St. Louistrain
10h 23m$170–298Drive to Wichita Mid-Continent Airport, fly
- Drive from Independence to Wichita Mid-Continent Airport (ICT)car
- Fly from Wichita Mid-Continent Airport (ICT) to Lambert–St. Louis International Airport (STL)plane ICT - STL
6h 58m$205–934Taxi to Joplin Regional Airport, fly
- Take the taxi from Independence to Joplin Regional Airport (JLN)taxi
- Fly from Joplin Regional Airport (JLN) to Lambert–St. Louis International Airport (STL)plane JLN - STL
8h 11m$184–687Bus to Kansas City, fly
- Take the bus from Coffeyville to Kansas Citybus
- Fly from Kansas City (MCI) to Lambert–St. Louis International Airport (STL)plane MCI - STL
8h 28m$141–682Bus to Tulsa International Airport, fly
- Take the bus from Coffeyville to Tulsabus
- Fly from Tulsa International Airport (TUL) to Lambert–St. Louis International Airport (STL)plane TUL - STL
9h 47m$213–906
Wichita Mid-Continent Airport (ICT) to Lambert–St. Louis International Airport (STL) flights
Questions & Answers
The cheapest way to get from Independence to St. Louis is to drive which costs $60 - $95 and takes 6h 14m.
The fastest way to get from Independence to St. Louis is to drive which takes 6h 14m and costs $60 - $95.
No, there is no direct bus from Independence to St. Louis station. However, there are services departing from Coffeyville and arriving at St Louis Bus Station via Kansas City Bus Station. The journey, including transfers, takes approximately 9h 3m.
The distance between Independence and St. Louis is 440 miles. The road distance is 354.3 miles.
The best way to get from Independence to St. Louis without a car is to bus which takes 9h 3m and costs $85 - $160.
It takes approximately 9h 3m to get from Independence to St. Louis, including transfers.
Independence to St. Louis bus services, operated by Jefferson Lines, depart from Coffeyville station.
Independence to St. Louis bus services, operated by Jefferson Lines, arrive at Kansas City station.
Yes, the driving distance between Independence to St. Louis is 354 miles. It takes approximately 6h 14m to drive from Independence to St. Louis.
There are 526+ hotels available in St. Louis.
What companies run services between Independence, KS, USA and St. Louis, MO, USA?
You can take a vehicle from Independence to St Louis Bus Station via Coffeyville and Kansas City Bus Station in around 9h 3m.
- Website
- southwest.com
Flights from Wichita Mid-Continent Airport to Lambert–St. Louis International Airport via Chicago Midway
- Ave. Duration
- 5h
- When
- Monday, Thursday, Friday, Sunday, and Saturday
- Estimated price
- $180–900
Flights from Wichita Mid-Continent Airport to Lambert–St. Louis International Airport via Denver
- Ave. Duration
- 5h 25m
- When
- Sunday, Monday, Thursday, and Friday
- Estimated price
- $230–1,100
Flights from Kansas City to Lambert–St. Louis International Airport
- Ave. Duration
- 1h 2m
- When
- Every day
- Estimated price
- $85–600
Flights from Tulsa International Airport to Lambert–St. Louis International Airport via Dallas
- Ave. Duration
- 4h 33m
- When
- Every day
- Estimated price
- $170–850
Flights from Tulsa International Airport to Lambert–St. Louis International Airport via Chicago Midway
- Ave. Duration
- 5h 25m
- When
- Sunday, Monday, Thursday, and Friday
- Estimated price
- $170–900
Flights from Tulsa International Airport to Lambert–St. Louis International Airport via Houston Hobby Apt
- Ave. Duration
- 5h 5m
- When
- Tuesday to Friday
- Estimated price
- $220–1,000
Flights from Tulsa International Airport to Lambert–St. Louis International Airport via Nashville
- Ave. Duration
- 6h 1m
- When
- Monday, Thursday, Friday, Tuesday, Wednesday, and Sunday
- Estimated price
- $170–850
Flights from Tulsa International Airport to Lambert–St. Louis International Airport via Austin
- Ave. Duration
- 5h 10m
- When
- Monday, Thursday, and Friday
- Estimated price
- $220–1,000
- Website
- aa.com
Flights from Wichita Mid-Continent Airport to Lambert–St. Louis International Airport via Dallas/Ft.Worth
- Ave. Duration
- 5h 23m
- When
- Every day
- Estimated price
- $190–950
Flights from Wichita Mid-Continent Airport to Lambert–St. Louis International Airport via Chicago O'Hare
- Ave. Duration
- 5h 40m
- When
- Every day
- Estimated price
- $180–900
Flights from Tulsa International Airport to Lambert–St. Louis International Airport via Dallas/Ft.Worth
- Ave. Duration
- 4h 29m
- When
- Every day
- Estimated price
- $170–850
Flights from Tulsa International Airport to Lambert–St. Louis International Airport via Chicago O'Hare
- Ave. Duration
- 6h 30m
- When
- Every day
- Estimated price
- $180–900
- Website
- united.com
Flights from Wichita Mid-Continent Airport to Lambert–St. Louis International Airport via Chicago O'Hare
- Ave. Duration
- 4h 42m
- When
- Every day
- Estimated price
- $180–900
Flights from Wichita Mid-Continent Airport to Lambert–St. Louis International Airport via Houston
- Ave. Duration
- 5h 13m
- When
- Sunday, Monday, and Thursday
- Estimated price
- $240–1,100
Flights from Wichita Mid-Continent Airport to Lambert–St. Louis International Airport via Denver
- Ave. Duration
- 6h 37m
- When
- Every day
- Estimated price
- $230–1,100
Flights from Joplin Regional Airport to Lambert–St. Louis International Airport via Chicago O'Hare
- Ave. Duration
- 5h 58m
- When
- Every day
- Estimated price
- $110–600
Flights from Joplin Regional Airport to Lambert–St. Louis International Airport via Denver
- Ave. Duration
- 6h 53m
- When
- Monday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $170–750
Flights from Tulsa International Airport to Lambert–St. Louis International Airport via Chicago O'Hare
- Ave. Duration
- 5h 45m
- When
- Every day
- Estimated price
- $180–900
- Website
- delta.com
Flights from Wichita Mid-Continent Airport to Lambert–St. Louis International Airport via Atlanta
- Ave. Duration
- 5h 44m
- When
- Every day
- Estimated price
- $250–1,100
Flights from Wichita Mid-Continent Airport to Lambert–St. Louis International Airport via Minneapolis
- Ave. Duration
- 5h 57m
- When
- Every day
- Estimated price
- $200–1,000
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Kansas City to St. Louis
- Ave. Duration
- 5h 40m
- Frequency
- Twice daily
- Estimated price
- $90–190
- Website
- https://www.amtrak.com/home.html
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from Coffeyville to Kansas City
- Ave. Duration
- 3h 30m
- Frequency
- Twice daily
- Estimated price
- $45–70
- Book at
- https://www.jeffersonlines.com
- Adult
- $45–70
Bus from Chanute to Kansas City
- Ave. Duration
- 2h 15m
- Frequency
- Twice daily
- Estimated price
- $35–55
- Book at
- https://www.jeffersonlines.com
- Adult
- $35–55
Bus from Coffeyville to Kansas City
- Ave. Duration
- 3h 30m
- Frequency
- Twice daily
- Estimated price
- $45–70
- Book at
- https://www.jeffersonlines.com
- Adult
- $45–70
Bus from Coffeyville to Tulsa
- Ave. Duration
- 1h 40m
- Frequency
- Twice daily
- Estimated price
- $29–40
- Book at
- https://www.jeffersonlines.com
- Adult
- $29–40
- Website
- greyhound.com
Bus from Kansas City Bus Station to St Louis Bus Station
- Ave. Duration
- 4h
- Frequency
- 4 times a day
- Schedules at
- greyhound.com
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- greyhound.com
Bus from Kansas City Bus Station to St Louis Bus Station
- Ave. Duration
- 4h
- Frequency
- 4 times a day
- Estimated price
- $35–75
- Website
- https://www.greyhound.com/
- Ave. Duration
- 1h 9m
- Estimated price
- $45–85
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide
Why you should take the train in the US
Read the travel guide









