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How to get fromIndependence to Cape Girardeauby train, bus, bus (Greyhound), car, plane, or taxi

Find Transport to Cape Girardeau

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There are 6 ways to get from Independence to Cape Girardeau by train, bus, bus (Greyhound), car, plane, or taxi

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train, bus

    best
    1. Take the train from Independence Station to St. Louistrain train Missouri River Runner / ...
    2. Take the bus from St Louis Bus Station to Cape Girardeaubus bus Greyhound US1173
    8h 30m
    $95–192

  2. Bus (Greyhound)

    cheapest
    1. Take the bus from Kansas City Bus Station to St Louis Bus Stationbus bus Greyhound US0180s / ...
    2. Take the bus from St Louis Bus Station to Cape Girardeaubus bus Greyhound US1173
    9h 1m
    $59–102

  3. Drive  338.9 mi

    1. Drive from Independence to Cape Girardeaucar car 338.9 mi
    5h 45m
    $62–90

  4. Fly to Williamson County Regional Airport, taxi

    1. Fly from Kansas City (MCI) to Williamson County Regional Airport (MWA)plane plane MCI - MWA
    2. Take the taxi from Williamson County Regional Airport (MWA) to Cape Girardeautaxi taxi
    8h 35m
    $230–760

  5. Line 24 bus, fly to Lambert–St. Louis International Airport, bus

    1. Take the bus from On Truman At Osage Wb to East Village - Bay Abus bus
    2. Fly from Kansas City (MCI) to Lambert–St. Louis International Airport (STL)plane plane MCI - STL
    3. Take the bus from St Louis Bus Station to Cape Girardeaubus bus
    8h 13m
    $727–1,040

  6. Fly to Barkley Regional Airport, taxi

    1. Fly from Kansas City (MCI) to Barkley Regional Airport (PAH)plane plane MCI - PAH
    2. Take the taxi from Barkley Regional Airport (PAH) to Cape Girardeautaxi taxi
    9h 3m
    $240–720

Kansas City (MCI) to Williamson County Regional Airport (MWA) flights

Calendar20Weekly Planes
Duration4h 30mAverage Duration
Ticket$108Cheapest Price
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Questions & Answers

Map of how to get from Independence to Cape Girardeau.ExpandLaunch map view
  • Distance: 384.4 mi
  • Duration: 8h 30m

What companies run services between Independence, MO, USA and Cape Girardeau, MO, USA?

You can take a bus from On Truman At Main Westbound to Cape Girardeau via East Village - Bay A, Kansas City Bus Station, St Louis Bus Station, and Cape Girardeau in around 9h 1m.

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