There are 8 ways to get from Independence to Louisville by train, bus, car, plane, or bus (Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train, bus
best- Take the train from Independence Station to St. Louistrain
- Take the bus from St Louis Bus Station to Evansville Bus Stationbus
- Take the bus from Evansville, IN to Louisville, KYbus
13h 1m$149–280Drive 498.5 mi
cheapest- Drive from Independence to Louisvillecar 498.5 mi
8h 19m$91–132Fly to Louisville International Airport
- Fly from Kansas City (MCI) to Louisville International Airport (SDF)plane MCI - SDF
7h 53m$131–753Bus
- Take the bus from Kansas City Bus Station to St Louis Bus Stationbus
- Take the bus from St Louis Bus Station to Evansville Bus Stationbus
- Take the bus from Evansville, IN to Louisville, KYbus
13h 31m$95–180Fly to Blue Grass Airport, drive
- Fly from Kansas City (MCI) to Blue Grass Airport (LEX)plane MCI - LEX
- Drive from Lexington-Airport-LEX to Louisvillecar
8h 45m$233–1,219Fly to Covington, bus
- Fly from Kansas City (MCI) to Covington (CVG)plane MCI - CVG
- Take the bus from Cincinnati - Downtown to Louisville, KY Bus Stationbus
10h 47m$161–847Fly to Indianapolis, bus
- Fly from Kansas City (MCI) to Indianapolis (IND)plane MCI - IND
- Take the bus from Indianapolis Union Station to Louisville, KYbus
9h 31m$682–1,063Fly to Nashville, bus
- Fly from Kansas City (MCI) to Nashville (BNA)plane MCI - BNA
- Take the bus from Nashville to Louisville, KYbus
10h 15m$122–602
Independence to Louisville by train and bus
Questions & Answers
The cheapest way to get from Independence to Louisville is to drive which costs $90 - $140 and takes 8h 19m.
The fastest way to get from Independence to Louisville is to fly which takes 7h 53m and costs $130 - $800.
No, there is no direct bus from Independence to Louisville. However, there are services departing from On Truman At Main Westbound and arriving at Louisville, KY via Kansas City Bus Station, St Louis Bus Station and Evansville, IN. The journey, including transfers, takes approximately 13h 31m.
The distance between Independence and Louisville is 556 miles. The road distance is 501.4 miles.
The best way to get from Independence to Louisville without a car is to train and bus which takes 13h 1m and costs $140 - $280.
It takes approximately 13h 1m to get from Independence to Louisville, including transfers.
Independence to Louisville bus services, operated by Greyhound USA, depart from Kansas City Bus Station.
The best way to get from Independence to Louisville is to fly which takes 7h 53m and costs $130 - $800. Alternatively, you can bus, which costs $95 - $180 and takes 13h 31m.
Independence to Louisville bus services, operated by Greyhound USA, arrive at St Louis Bus Station.
Louisville is 1h ahead of Independence. It is currently 10:06 PM in Independence and 11:06 PM in Louisville.
What companies run services between Independence, MO, USA and Louisville, KY, USA?
Southwest Airlines, Delta, and two other airlines fly from Kansas City (MCI) to Louisville International Airport (SDF) hourly. Alternatively, you can take a bus from On Truman At Main Westbound to Louisville, KY via East Village - Bay A, Kansas City Bus Station, St Louis Bus Station, and Evansville, IN in around 13h 31m.
- Website
- southwest.com
Flights from Kansas City to Louisville International Airport via Nashville
- Ave. Duration
- 3h 50m
- When
- Tuesday, Wednesday, Saturday, and Sunday
- Estimated price
- $130–750
Flights from Kansas City to Louisville International Airport via Chicago Midway
- Ave. Duration
- 4h
- When
- Every day
- Estimated price
- $140–750
Flights from Kansas City to Louisville International Airport via Dallas
- Ave. Duration
- 4h 35m
- When
- Tuesday and Wednesday
- Estimated price
- $200–950
Flights from Kansas City to Covington via Chicago Midway
- Ave. Duration
- 4h 5m
- When
- Every day
- Estimated price
- $150–800
Flights from Kansas City to Covington via Nashville
- Ave. Duration
- 3h 56m
- When
- Tuesday to Friday
- Estimated price
- $160–850
Flights from Kansas City to Indianapolis
- Ave. Duration
- 1h 27m
- When
- Every day
- Estimated price
- $110–700
Flights from Kansas City to Indianapolis via Chicago Midway
- Ave. Duration
- 3h 30m
- When
- Saturday, Tuesday, and Wednesday
- Estimated price
- $130–750
Flights from Kansas City to Indianapolis via Nashville
- Ave. Duration
- 3h 45m
- When
- Tuesday and Wednesday
- Estimated price
- $150–800
Flights from Kansas City to Nashville
- Ave. Duration
- 1h 35m
- When
- Every day
- Estimated price
- $90–550
Flights from Kansas City to Nashville via St. Louis
- Ave. Duration
- 3h 43m
- When
- Tuesday, Wednesday, and Sunday
- Estimated price
- $95–550
Flights from Kansas City to Nashville via Indianapolis
- Ave. Duration
- 3h 35m
- When
- Saturday
- Estimated price
- $110–600
Flights from Kansas City to Nashville via Chicago Midway
- Ave. Duration
- 3h 58m
- When
- Tuesday, Wednesday, Sunday, and Saturday
- Estimated price
- $120–650
- Website
- delta.com
Flights from Kansas City to Louisville International Airport via Atlanta
- Ave. Duration
- 4h 54m
- When
- Every day
- Estimated price
- $180–900
Flights from Kansas City to Louisville International Airport via Minneapolis
- Ave. Duration
- 5h 25m
- When
- Every day
- Estimated price
- $180–900
Flights from Kansas City to Louisville International Airport via Detroit
- Ave. Duration
- 5h 11m
- When
- Every day
- Estimated price
- $170–850
Flights from Kansas City to Blue Grass Airport via Atlanta
- Ave. Duration
- 4h 43m
- When
- Every day
- Estimated price
- $270–1,300
Flights from Kansas City to Blue Grass Airport via Minneapolis
- Ave. Duration
- 5h 33m
- When
- Saturday
- Estimated price
- $280–1,400
Flights from Kansas City to Blue Grass Airport via Detroit
- Ave. Duration
- 6h 4m
- When
- Every day
- Estimated price
- $260–1,300
Flights from Kansas City to Covington via Detroit
- Ave. Duration
- 4h 26m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $170–900
Flights from Kansas City to Covington via Atlanta
- Ave. Duration
- 4h 26m
- When
- Every day
- Estimated price
- $210–1,000
Flights from Kansas City to Covington via Minneapolis
- Ave. Duration
- 4h 54m
- When
- Every day
- Estimated price
- $190–950
- Website
- united.com
Flights from Kansas City to Louisville International Airport via Chicago O'Hare
- Ave. Duration
- 4h 53m
- When
- Every day
- Estimated price
- $140–750
Flights from Kansas City to Blue Grass Airport via Chicago O'Hare
- Ave. Duration
- 5h 3m
- When
- Every day
- Estimated price
- $220–1,200
Flights from Kansas City to Covington via Chicago O'Hare
- Ave. Duration
- 4h 27m
- When
- Every day
- Estimated price
- $150–800
- Website
- aa.com
Flights from Kansas City to Louisville International Airport via Chicago O'Hare
- Ave. Duration
- 4h 38m
- When
- Every day
- Estimated price
- $140–750
Flights from Kansas City to Blue Grass Airport via Chicago O'Hare
- Ave. Duration
- 6h 49m
- When
- Every day
- Estimated price
- $220–1,200
Flights from Kansas City to Blue Grass Airport via Charlotte
- Ave. Duration
- 6h 1m
- When
- Every day
- Estimated price
- $290–1,400
Flights from Kansas City to Covington via Chicago O'Hare
- Ave. Duration
- 4h 35m
- When
- Every day
- Estimated price
- $150–800
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Independence Station to St. Louis
- Ave. Duration
- 5h 21m
- Frequency
- Twice daily
- Estimated price
- $85–180
- Website
- https://www.amtrak.com/home.html
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- greyhound.com
Bus from St Louis Bus Station to Evansville Bus Station
- Ave. Duration
- 3h 25m
- Frequency
- Twice daily
- Estimated price
- $25–50
- Website
- https://www.greyhound.com/
Bus from Kansas City Bus Station to St Louis Bus Station
- Ave. Duration
- 4h
- Frequency
- 4 times a day
- Estimated price
- $35–75
- Website
- https://www.greyhound.com/
Bus from St Louis Bus Station to Evansville Bus Station
- Ave. Duration
- 3h 25m
- Frequency
- Twice daily
- Estimated price
- $25–50
- Website
- https://www.greyhound.com/
- Phone
- +1 502-368-5644 x 135
- Website
- ridewithmiller.com
Bus from Evansville, IN to Louisville, KY
- Ave. Duration
- 2h 15m
- Frequency
- Once daily
- Estimated price
- $35–55
- Website
- https://ridewithmiller.com
Bus from Evansville, IN to Louisville, KY
- Ave. Duration
- 2h 15m
- Frequency
- Once daily
- Estimated price
- $35–55
- Website
- https://ridewithmiller.com
- Phone
- +1 888-378-3823
- [email protected]
- Website
- baronsbus.com
Bus from Cincinnati - Downtown to Louisville, KY Bus Station
- Ave. Duration
- 1h 50m
- Frequency
- Once daily
- Estimated price
- $9–45
- Website
- https://baronsbus.com
Rome2Rio's guide to Amtrak Thruway
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Bus from Indianapolis Union Station to Louisville, KY
- Ave. Duration
- 2h 25m
- Frequency
- Twice daily
- Estimated price
- $22–45
- Website
- https://www.amtrak.com/home.html
- Adult
- $22–45
Bus from Nashville to Louisville, KY
- Ave. Duration
- 3h 40m
- Frequency
- Twice daily
- Estimated price
- $30–50
- Website
- https://www.amtrak.com/home.html
- Adult
- $30–50
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More Questions & Answers
Yes, the driving distance between Independence to Louisville is 501 miles. It takes approximately 8h 19m to drive from Independence to Louisville.
There are 539+ hotels available in Louisville.














