There are 7 ways to get from Independence to Louisville by train, bus, car, plane, or bus (Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train, bus
best- Take the train from Independence Station to St. Louistrain
- Take the bus from St Louis Bus Station to Evansville Bus Stationbus
- Take the bus from Evansville, IN to Louisville, KYbus
13h 1m$212–402Drive 498.5 mi
cheapest- Drive from Independence to Louisvillecar 498.5 mi
8h 19m$91–132Fly to Louisville International Airport
- Fly from Kansas City (MCI) to Louisville International Airport (SDF)plane MCI - SDF
7h 53m$171–953Bus
- Take the bus from Kansas City Bus Station to St Louis Bus Stationbus
- Take the bus from St Louis Bus Station to Evansville Bus Stationbus
- Take the bus from Evansville, IN to Louisville, KYbus
13h 31m$104–245Fly to Blue Grass Airport, drive
- Fly from Kansas City (MCI) to Blue Grass Airport (LEX)plane MCI - LEX
- Drive from Lexington-Airport-LEX to Louisvillecar
8h 50m$113–569Fly to Indianapolis, bus
- Fly from Kansas City (MCI) to Indianapolis (IND)plane MCI - IND
- Take the bus from Indianapolis Union Station to Louisville, KYbus
8h 56m$682–1,159Fly to Nashville, bus
- Fly from Kansas City (MCI) to Nashville (BNA)plane MCI - BNA
- Take the bus from Nashville to Louisville, KYbus
10h 10m$432–1,152
Independence to Louisville by train and bus
Comparing Your Travel Options
The cheapest way to get from Independence to Louisville is to drive which costs $90 - $140 and takes 8h 19m.
The fastest way to get from Independence to Louisville is to fly which takes 7h 53m and costs $170 - $1,000.
No, there is no direct bus from Independence to Louisville. However, there are services departing from On Truman At Main Westbound and arriving at Louisville, KY via Kansas City Bus Station, St Louis Bus Station and Evansville, IN. The journey, including transfers, takes approximately 13h 31m.
The distance between Independence and Louisville is 556 miles. The road distance is 501.4 miles.
The best way to get from Independence to Louisville without a car is to train and bus which takes 13h 1m and costs $210 - $410.
It takes approximately 13h 1m to get from Independence to Louisville, including transfers.
Independence to Louisville bus services, operated by Greyhound USA, depart from Kansas City Bus Station.
The best way to get from Independence to Louisville is to fly which takes 7h 53m and costs $170 - $1,000. Alternatively, you can bus, which costs $100 - $250 and takes 13h 31m.
Independence to Louisville bus services, operated by Greyhound USA, arrive at St Louis Bus Station.
Louisville is 1h ahead of Independence. It is currently 5:25 PM in Independence and 6:25 PM in Louisville.
What companies run services between Independence, MO, USA and Louisville, KY, USA?
Southwest Airlines, United Airlines, and two other airlines fly from Kansas City (MCI) to Louisville International Airport (SDF) hourly. Alternatively, you can take a bus from On Truman At Main Westbound to Louisville, KY via East Village - Bay A, Kansas City Bus Station, St Louis Bus Station, and Evansville, IN in around 13h 31m.
- Website
- southwest.com
Flights from Kansas City to Louisville International Airport via Nashville
- Ave. Duration
- 3h 37m
- When
- Saturday, Monday, Sunday, Thursday, and Friday
- Estimated price
- $170–950
Flights from Kansas City to Louisville International Airport via Chicago Midway
- Ave. Duration
- 3h 36m
- When
- Every day
- Estimated price
- $170–1,000
Flights from Kansas City to Indianapolis
- Ave. Duration
- 1h 23m
- When
- Every day
- Estimated price
- $110–700
Flights from Kansas City to Indianapolis via Chicago Midway
- Ave. Duration
- 3h 23m
- When
- Monday to Wednesday
- Estimated price
- $120–750
Flights from Kansas City to Nashville
- Ave. Duration
- 1h 33m
- When
- Every day
- Estimated price
- $90–600
Flights from Kansas City to Nashville via St. Louis
- Ave. Duration
- 3h 21m
- When
- Saturday to Wednesday
- Estimated price
- $95–600
- Website
- aa.com
Flights from Kansas City to Louisville International Airport via Chicago O'Hare
- Ave. Duration
- 4h 26m
- When
- Tuesday, Wednesday, Thursday, Friday, Sunday, and Monday
- Estimated price
- $180–1,000
Flights from Kansas City to Blue Grass Airport via Chicago O'Hare
- Ave. Duration
- 4h 41m
- When
- Every day
- Estimated price
- $100–550
Flights from Kansas City to Blue Grass Airport via Charlotte
- Ave. Duration
- 5h 4m
- When
- Every day
- Estimated price
- $130–650
Flights from Kansas City to Blue Grass Airport via Dallas/Ft.Worth
- Ave. Duration
- 5h 51m
- When
- Friday to Thursday
- Estimated price
- $140–700
- Website
- delta.com
Flights from Kansas City to Louisville International Airport via Minneapolis
- Ave. Duration
- 4h 28m
- When
- Every day
- Estimated price
- $220–1,200
Flights from Kansas City to Louisville International Airport via Atlanta
- Ave. Duration
- 4h 50m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $220–1,200
Flights from Kansas City to Blue Grass Airport via Atlanta
- Ave. Duration
- 5h 18m
- When
- Every day
- Estimated price
- $120–650
Flights from Kansas City to Blue Grass Airport via Detroit
- Ave. Duration
- 5h 44m
- When
- Every day
- Estimated price
- $110–600
- Website
- united.com
Flights from Kansas City to Louisville International Airport via Chicago O'Hare
- Ave. Duration
- 4h 29m
- When
- Every day
- Estimated price
- $180–1,000
Flights from Kansas City to Blue Grass Airport via Chicago O'Hare
- Ave. Duration
- 4h 38m
- When
- Every day
- Estimated price
- $100–550
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Independence Station to St. Louis
- Ave. Duration
- 5h 21m
- Frequency
- Twice daily
- Estimated price
- $140–230
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from St Louis Bus Station to Evansville Bus Station
- Ave. Duration
- 3h 25m
- Frequency
- Twice daily
- Estimated price
- $29–45
- Website
- Greyhound
Bus from Kansas City Bus Station to St Louis Bus Station
- Ave. Duration
- 4h
- Frequency
- 4 times a day
- Estimated price
- $40–70
- Website
- Greyhound
Bus from St Louis Bus Station to Evansville Bus Station
- Ave. Duration
- 3h 25m
- Frequency
- Twice daily
- Estimated price
- $29–45
- Website
- Greyhound
- Phone
- +1 502-368-5644 x 135
- Website
- Miller Transportation
Bus from Evansville, IN to Louisville, KY
- Ave. Duration
- 2h 15m
- Frequency
- Once daily
- Estimated price
- $35–130
- Website
- Miller Transportation
Bus from Evansville, IN to Louisville, KY
- Ave. Duration
- 2h 15m
- Frequency
- Once daily
- Estimated price
- $35–130
- Website
- Miller Transportation
Rome2Rio's guide to Amtrak Thruway
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Bus from Indianapolis Union Station to Louisville, KY
- Ave. Duration
- 1h 55m
- Frequency
- Twice daily
- Estimated price
- $22–45
- Website
- Amtrak
- Adult
- $22–45
Bus from Nashville to Louisville, KY
- Ave. Duration
- 3h 40m
- Frequency
- Twice daily
- Estimated price
- $30–50
- Website
- Amtrak
- Adult
- $30–50
Want to know more about travelling around United States
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Booking & Getting There
Yes, the driving distance between Independence to Louisville is 501 miles. It takes approximately 8h 19m to drive from Independence to Louisville.
There are 614+ hotels available in Louisville.










