There are 6 ways to get from Independence to San Antonio by bus, plane, bus (Flixbus), train (Amtrak), or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Line 24 bus to Kansas City, fly to San Antonio International Airport, line 7 bus
best- Take the bus from On Truman At Osage Wb to East Village - Bay Abus
- Fly from Kansas City (MCI) to San Antonio International Airport (SAT)plane MCI - SAT
- Take the bus from San Antonio International Airport to St. Mary's & Pecanbus
6h 7m$142–802Bus (Flixbus)
cheapest- Take the bus from Kansas City Bus Station to Dentonbus FlixBus 2241
- Take the bus from Denton to San Antonio Bus Stationbus FlixBus 2230
19h 41m$125–195Train (Amtrak)
- Take the train from Independence Station to St. Louistrain Missouri River Runner / ...
- Take the train from St. Louis to San Antonio Stationtrain Texas Eagle
32h 57m$305–755Drive 766.4 mi
- Drive from Independence to San Antoniocar 766.4 mi
12h 56m$140–202Drive to Manhattan Regional Airport, fly to San Antonio International Airport
- Drive from Independence to Manhattan Regional Airport (MHK)car
- Fly from Manhattan Regional Airport (MHK) to San Antonio International Airport (SAT)plane MHK - SAT
7h 13m$127–637Fly Kansas City to Austin-Bergstrom International Airport, bus
- Fly from Kansas City (MCI) to Austin-Bergstrom International Airport (AUS)plane MCI - AUS
- Take the bus from Austin, TX - UT Austin to San Antonio, TX - E Commerce Stbus
8h 53m$150–370
Independence to San Antonio by bus and foot (Flixbus)
Comparing Your Travel Options
The cheapest way to get from Independence to San Antonio is to bus which costs $120 - $200 and takes 19h 41m.
The fastest way to get from Independence to San Antonio is to line 24 bus and fly and line 7 bus which takes 6h 7m and costs $140 - $800.
No, there is no direct bus from Independence to San Antonio station. However, there are services departing from On Truman At Main Westbound and arriving at San Antonio Bus Station via Kansas City Bus Station and Denton. The journey, including transfers, takes approximately 19h 41m.
No, there is no direct train from Independence station to San Antonio station. However, there are services departing from Independence Station and arriving at San Antonio Station via St. Louis. The journey, including transfers, takes approximately 32h 57m.
The distance between Independence and San Antonio is 756 miles. The road distance is 770.8 miles.
The best way to get from Independence to San Antonio without a car is to bus which takes 19h 41m and costs $120 - $200.
It takes approximately 6h 7m to get from Independence to San Antonio, including transfers.
Independence to San Antonio bus services, operated by Flixbus USA, depart from Kansas City Bus Station.
Independence to San Antonio train services, operated by Amtrak, depart from Independence Station.
The best way to get from Independence to San Antonio is to bus which takes 19h 41m and costs $120 - $200. Alternatively, you can train, which costs $300 - $800 and takes 32h 57m.
What companies run services between Independence, MO, USA and San Antonio, TX, USA?
You can take a bus from On Truman At Main Westbound to San Antonio Bus Station via East Village - Bay A, Kansas City Bus Station, and Denton in around 19h 41m. Alternatively, you can take a train from Independence Station to San Antonio Station via St. Louis in around 32h 57m.
- Website
- southwest.com
Flights from Kansas City to San Antonio International Airport
- Ave. Duration
- 2h
- When
- Sunday, Monday, Tuesday, Wednesday, Thursday, and Friday
- Estimated price
- $140–800
Flights from Kansas City to San Antonio International Airport via Dallas
- Ave. Duration
- 3h 52m
- When
- Every day
- Estimated price
- $140–800
Flights from Kansas City to San Antonio International Airport via Houston Hobby Apt
- Ave. Duration
- 3h 58m
- When
- Saturday, Sunday, Tuesday, and Wednesday
- Estimated price
- $160–850
Flights from Kansas City to San Antonio International Airport via St. Louis
- Ave. Duration
- 4h 10m
- When
- Monday, Thursday, and Friday
- Estimated price
- $180–900
Flights from Kansas City to Austin-Bergstrom International Airport
- Ave. Duration
- 1h 54m
- When
- Every day
- Estimated price
- $120–700
Flights from Kansas City to Austin-Bergstrom International Airport via Houston Hobby Apt
- Ave. Duration
- 3h 52m
- When
- Every day
- Estimated price
- $130–750
Flights from Kansas City to Austin-Bergstrom International Airport via Dallas
- Ave. Duration
- 3h 57m
- When
- Sunday, Tuesday, Wednesday, and Saturday
- Estimated price
- $120–700
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Independence Station to St. Louis
- Ave. Duration
- 5h 21m
- Frequency
- Twice daily
- Estimated price
- $65–160
- Website
- Amtrak
Train from St. Louis to San Antonio Station
- Ave. Duration
- 26h 36m
- Frequency
- Once daily
- Estimated price
- $240–600
- Website
- Amtrak
- Phone
- +1 816-221-0660
- Website
- Ride KC
Bus from On Truman At Osage Wb to East Village - Bay A
- Ave. Duration
- 45 min
- Frequency
- Hourly
- Schedules at
- Ride KC
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Booking & Getting There
Independence to San Antonio bus services, operated by Flixbus USA, arrive at Denton station.
Independence to San Antonio train services, operated by Amtrak, arrive at St. Louis station.
Yes, the driving distance between Independence to San Antonio is 771 miles. It takes approximately 12h 56m to drive from Independence to San Antonio.
Book your Independence to San Antonio train tickets online with Omio.
There are 1332+ hotels available in San Antonio.




