There are 6 ways to get from Indiana to Cape Girardeau by bus, train, taxi, car, plane, or bus (Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus, train, taxi
best- Take the bus from Indianapolis Union Station to Champaign Intermodal Trans Ctrbus
- Take the train from Champaign-Urbana to Carbondaletrain
- Take the taxi from Carbondale to Cape Girardeautaxi
6h 59m$164–272Drive 304.2 mi
cheapest- Drive from Indianapolis to Cape Girardeaucar 304.2 mi
5h 10m$56–81Train to Chicago O'Hare International Airport, fly to Williamson County Regional Airport, taxi
- Take the train from Gary to Van Buren St.train
- Fly from Chicago O'Hare International Airport (ORD) to Williamson County Regional Airport (MWA)plane ORD - MWA
- Take the taxi from Williamson County Regional Airport (MWA) to Cape Girardeautaxi
5h 23m$220–393Bus (Greyhound)
- Take the bus from Indianapolis Union Station to St Louis Bus Stationbus Greyhound US0421
- Take the bus from St Louis Bus Station to Cape Girardeaubus Greyhound US1173
7h 4m$62–103Train to Chicago O'Hare International Airport, fly to Barkley Regional Airport, taxi
- Take the train from Gary to Van Buren St.train
- Fly from Chicago O'Hare International Airport (ORD) to Barkley Regional Airport (PAH)plane ORD - PAH
- Take the taxi from Barkley Regional Airport (PAH) to Cape Girardeautaxi
5h 41m$195–473Train to Chicago Midway International Airport, fly to Lambert–St. Louis International Airport, bus
- Take the train from Gary to Museum Campus/11th Street Sationtrain
- Fly from Chicago Midway International Airport (MDW) to Lambert–St. Louis International Airport (STL)plane MDW - STL
- Take the bus from St Louis Bus Station to Cape Girardeaubus
7h 35m$106–555
Chicago O'Hare International Airport (ORD) to Williamson County Regional Airport (MWA) flights
Questions & Answers
The cheapest way to get from Indiana to Cape Girardeau is to drive which costs $55 - $80 and takes 5h 10m.
The fastest way to get from Indiana to Cape Girardeau is to drive which takes 5h 10m and costs $55 - $80.
No, there is no direct bus from Indiana station to Cape Girardeau. However, there are services departing from Indianapolis Union Station and arriving at Cape Girardeau via St Louis Bus Station. The journey, including transfers, takes approximately 7h 4m.
The distance between Indiana and Cape Girardeau is 348 miles. The road distance is 306 miles.
The best way to get from Indiana to Cape Girardeau without a car is to bus and train and taxi which takes 6h 59m and costs $160 - $280.
It takes approximately 6h 59m to get from Indiana to Cape Girardeau, including transfers.
Indiana to Cape Girardeau bus services, operated by Greyhound USA, depart from Indianapolis Union Station.
Indiana to Cape Girardeau bus services, operated by Greyhound USA, arrive at St Louis Bus Station.
Cape Girardeau is 1h behind Indiana. It is currently 1:46 PM in Indiana and 12:46 PM in Cape Girardeau.
Yes, the driving distance between Indiana to Cape Girardeau is 306 miles. It takes approximately 5h 10m to drive from Indiana to Cape Girardeau.
What companies run services between Indiana, USA and Cape Girardeau, MO, USA?
You can take a bus from Indianapolis Union Station to Cape Girardeau via St Louis Bus Station and Cape Girardeau in around 7h 4m.
- Website
- southwest.com
Flights from Chicago Midway International Airport to Lambert–St. Louis International Airport
- Ave. Duration
- 1h 11m
- When
- Every day
- Estimated price
- $70–500
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Champaign-Urbana to Carbondale
- Ave. Duration
- 2h 54m
- Frequency
- 3 times a day
- Estimated price
- $45–110
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Indianapolis Union Station to Champaign Intermodal Trans Ctr
- Ave. Duration
- 2h 5m
- Frequency
- Once daily
- Estimated price
- $18–35
- Website
- Greyhound
Bus from Indianapolis Union Station to St Louis Bus Station
- Ave. Duration
- 3h 55m
- Frequency
- 3 times a day
- Estimated price
- $35–65
- Website
- Greyhound
Bus from St Louis Bus Station to Cape Girardeau
- Ave. Duration
- 2h 5m
- Frequency
- Once daily
- Estimated price
- $17–30
- Website
- Greyhound
Bus from St Louis Bus Station to Cape Girardeau
- Ave. Duration
- 2h 5m
- Frequency
- Once daily
- Estimated price
- $17–30
- Website
- Greyhound
- Ave. Duration
- 1h 13m
- Estimated price
- $100–170
Ace Taxi
- Phone
- +1 216-361-4700
- Website
- acetaxi.com
Ace Taxi
- Phone
- +1 216-361-4700
- Website
- acetaxi.com
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More Questions & Answers
There are 25+ hotels available in Cape Girardeau.





