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How to get fromIndiana to Great Smoky Mountainsby train, plane, car, or bus

Find Transport to Great Smoky Mountains

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There are 8 ways to get from Indiana to Great Smoky Mountains by train, plane, car, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train to Chicago O'Hare International Airport, fly to Mcghee Tyson Airport, drive

    best
    1. Take the train from Gary to Van Buren St.train train
    2. Fly from Chicago O'Hare International Airport (ORD) to Mcghee Tyson Airport (TYS)plane plane ORD - TYS
    3. Drive from Mcghee Tyson Airport (TYS) to Great Smoky Mountainscar car
    6h 28m
    $120–629

  2. Drive 403.2 mi

    cheapest
    1. Drive from Indianapolis to Great Smoky Mountainscar car 403.2 mi
    7h 47m
    $74–107

  3. Bus, drive

    1. Take the bus from Indianapolis to Columbusbus bus
    2. Take the bus from Columbus to Winston Salem(Trans Center)bus bus
    3. Take the bus from Winston Salem(Trans Center) to Asheville, NCbus bus
    4. Drive from Asheville, NC to Great Smoky Mountainscar car
    19h 57m
    $127–247

  4. Train, bus, drive

    1. Take the train from Indianapolis to Charlottesvilletrain train
    2. Take the train from Charlottesville to Greensborotrain train
    3. Take the bus from Greensboro Bus Stop to Asheville, NCbus bus
    4. Drive from Asheville, NC to Great Smoky Mountainscar car
    26h 11m
    $292–590

  5. Train to Chicago O'Hare International Airport, fly to Asheville Regional Airport, drive

    1. Take the train from Gary to Van Buren St.train train
    2. Fly from Chicago O'Hare International Airport (ORD) to Asheville Regional Airport (AVL)plane plane ORD - AVL
    3. Drive from Asheville-Airport-AVL to Great Smoky Mountainscar car
    6h 48m
    $84–375

  6. Train to Chicago Midway International Airport, fly to Mcghee Tyson Airport, drive

    1. Take the train from Gary to Museum Campus/11th Street Sationtrain train
    2. Fly from Chicago Midway International Airport (MDW) to Mcghee Tyson Airport (TYS)plane plane MDW - TYS
    3. Drive from Mcghee Tyson Airport (TYS) to Great Smoky Mountainscar car
    5h 55m
    $139–779

  7. Train to Chicago O'Hare International Airport, fly to Greenville–Spartanburg International Airport, drive

    1. Take the train from Gary to Van Buren St.train train
    2. Fly from Chicago O'Hare International Airport (ORD) to Greenville–Spartanburg International Airport (GSP)plane plane ORD - GSP
    3. Drive from Greenville–Spartanburg International Airport (GSP) to Great Smoky Mountainscar car
    7h 58m
    $129–598

  8. Train, bus, drive via Ironville

    1. Take the train from Indianapolis to Ashland Amtrak Stationtrain train
    2. Take the bus from Ashland Bus Station to Winston Salem(Trans Center)bus bus
    3. Take the bus from Winston Salem(Trans Center) to Asheville, NCbus bus
    4. Drive from Asheville, NC to Great Smoky Mountainscar car
    20h 8m
    $168–333

Chicago O'Hare International Airport (ORD) to Mcghee Tyson Airport (TYS) flights

Calendar75Weekly Planes
Duration2h 58mAverage Duration
Ticket$103Cheapest Price
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Questions & Answers

Map of how to get from Indiana to Great Smoky Mountains.ExpandLaunch map view
  • Distance: 582.5 mi
  • Duration: 6h 28m

What companies run services between Indiana, USA and Great Smoky Mountains, TN, USA?

There is no direct connection from Indiana to Great Smoky Mountains. However, you can take the train to Van Buren St., walk to Jackson-Blue, take the subway to O'Hare, walk to Chicago O'Hare International Airport (ORD) airport, fly to Mcghee Tyson Airport (TYS), then drive to Great Smoky Mountains. Alternatively, you can take a bus from Indianapolis to Great Smoky Mountains via Columbus, S 3Rd St & E Town St, E Livingston Ave & Macon Aly, Columbus, Winston Salem(Trans Center), and Asheville, NC in around 19h 57m.

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