Rome2Rio

How to get fromIndiana to Port Saint Lucieby plane, car, bus (Flixbus), bus, train, or bus (Greyhound)

Find Transport to Port Saint Lucie

See all options

There are 7 ways to get from Indiana to Port Saint Lucie by plane, car, bus (Flixbus), bus, train, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Indianapolis to Orlando Sanford, drive

    best
    1. Fly from Indianapolis (IND) to Orlando Sanford (SFB)plane plane IND - SFB
    2. Drive from Orlando-Sanford-Airport-SFB to Port Saint Luciecar car
    6h 23m
    $121–587

  2. Bus (Flixbus)

    1. Take the bus from Indianapolis to Atlanta Bus Stationbus bus FlixBus 2512
    2. Take the bus from Atlanta Bus Station to Port St Luciebus bus FlixBus N2401
    24h 19m
    $170–257

  3. Drive  1,039.3 mi

    1. Drive from Indianapolis to Port Saint Luciecar car 1,039.3 mi
    18h 20m
    $190–274

  4. Fly Indianapolis to Fort Lauderdale–Hollywood International Airport, bus

    1. Fly from Indianapolis (IND) to Fort Lauderdale–Hollywood International Airport (FLL)plane plane IND - FLL
    2. Take the bus from Fort Lauderdale - Broward Blvd Park and Ride to Fort Piercebus bus
    7h 58m
    $532–1,247

  5. Fly Indianapolis to Orlando, bus

    1. Fly from Indianapolis (IND) to Orlando (MCO)plane plane IND - MCO
    2. Take the bus from Kissimmee -1471 East Osceola Parkway to Fort Piercebus bus
    8h 27m
    $206–796

  6. Train to Chicago Midway International Airport, fly to Orlando, bus

    1. Take the train from Gary to Museum Campus/11th Street Sationtrain train
    2. Fly from Chicago Midway International Airport (MDW) to Orlando (MCO)plane plane MDW - MCO
    3. Take the bus from Kissimmee -1471 East Osceola Parkway to Fort Piercebus bus
    9h 34m
    $234–548

  7. Bus via Fort Pierce (Greyhound)

    1. Take the bus from Indianapolis Union Station to Atlanta Bus Stationbus bus Greyhound US0100
    2. Take the bus from Atlanta Bus Station to Fort Piercebus bus Greyhound US0630
    28h 39m
    $178–278

Indiana to Port Saint Lucie by bus (Flixbus)

Calendar7Weekly Buses
Duration24h 19mAverage Duration
Ticket$170Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from Indiana to Port Saint Lucie.ExpandLaunch map view
  • Distance: 956.3 mi
  • Duration: 6h 23m

What companies run services between Indiana, USA and Port Saint Lucie, FL, USA?

You can take a bus from Indianapolis to SW PSL Blvd & Cameo Blvd - East via Atlanta Bus Station and SW Gatlin Blvd & SW Brescia St in around 24h 19m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound