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How to get fromIndiana to Sikestonby bus, taxi, train, car, plane, or bus (Greyhound)

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There are 7 ways to get from Indiana to Sikeston by bus, taxi, train, car, plane, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus, taxi

    best
    1. Take the bus from Indianapolis Union Station to St Louis Bus Stationbus bus
    2. Take the bus from St Louis Bus Station to Cape Girardeaubus bus
    3. Take the taxi from Cape Girardeau to Sikestontaxi taxi
    7h 35m
    $140–214

  2. Drive 327.6 mi

    cheapest
    1. Drive from Indianapolis to Sikestoncar car 327.6 mi
    5h 24m
    $60–87

  3. Bus, train, drive

    1. Take the bus from Indianapolis Union Station to Champaign Intermodal Trans Ctrbus bus
    2. Take the train from Champaign-Urbana to Fulton Amtrak Stationtrain train
    3. Drive from Fulton Amtrak Station to Sikestoncar car
    9h 31m
    $99–221

  4. Train to Chicago O'Hare International Airport, fly to Barkley Regional Airport, drive

    1. Take the train from Gary to Van Buren St.train train
    2. Fly from Chicago O'Hare International Airport (ORD) to Barkley Regional Airport (PAH)plane plane ORD - PAH
    3. Drive from Barkley Regional Airport (PAH) to Sikestoncar car
    5h 32m
    $65–318

  5. Bus

    1. Take the bus from Indianapolis Union Station to Champaign Intermodal Trans Ctrbus bus Greyhound US0157S
    2. Take the bus from Road Ranger Truck Stop - Champaign to Flying J - Matthewsbus bus Milwaukee
    8h 28m
    $115–164

  6. Train to Chicago O'Hare International Airport, fly to Williamson County Regional Airport, bus

    1. Take the train from Gary to Van Buren St.train train
    2. Fly from Chicago O'Hare International Airport (ORD) to Williamson County Regional Airport (MWA)plane plane ORD - MWA
    3. Take the bus from Marathon Gas Station - Marion to Flying J - Matthewsbus bus
    7h 1m
    $145–314

  7. Train to Chicago Midway International Airport, fly to Lambert–St. Louis International Airport, bus, taxi

    1. Take the train from Gary to Museum Campus/11th Street Sationtrain train
    2. Fly from Chicago Midway International Airport (MDW) to Lambert–St. Louis International Airport (STL)plane plane MDW - STL
    3. Take the bus from St Louis Bus Station to Cape Girardeaubus bus
    4. Take the taxi from Cape Girardeau to Sikestontaxi taxi
    8h 6m
    $188–666

Chicago O'Hare International Airport (ORD) to Barkley Regional Airport (PAH) flights

Calendar7Weekly Planes
Duration1h 30mAverage Duration
Ticket$45Cheapest Price
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Questions & Answers

Map of how to get from Indiana to Sikeston.ExpandLaunch map view
  • Distance: 388.4 mi
  • Duration: 7h 35m

What companies run services between Indiana, USA and Sikeston, MO, USA?

You can take a bus from Indianapolis Union Station to Sikeston via Champaign Intermodal Trans Ctr, Road Ranger Truck Stop - Champaign, and Flying J - Matthews in around 8h 28m.

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Train operators
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