There are 9 ways to get from Indiana to Spartanburg by train, plane, bus (Flixbus), train (Amtrak), car, or bus (Greyhound, Flixbus)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train to Chicago O'Hare International Airport, fly to Greenville–Spartanburg International Airport
best- Take the train from Gary to Van Buren St.train
- Fly from Chicago O'Hare International Airport (ORD) to Greenville–Spartanburg International Airport (GSP)plane ORD - GSP
5h 13m$155–633Train to Chicago O'Hare International Airport, fly to Asheville Regional Airport, drive
cheapest- Take the train from Gary to Van Buren St.train
- Fly from Chicago O'Hare International Airport (ORD) to Asheville Regional Airport (AVL)plane ORD - AVL
- Drive from Asheville-Airport-AVL to Spartanburgcar
5h 38m$74–358Bus via Atlanta
- Take the bus from Indianapolis to Atlanta Bus Stationbus FlixBus 2512
- Take the bus from Atlanta to Servicios Zapata - Spartanburgbus Charlotte
17h 4m$132–209Train (Amtrak)
- Take the train from Indianapolis to Charlottesvilletrain Cardinal
- Take the train from Charlottesville to Spartanburg Stationtrain Crescent
23h 49m$245–553Drive 493.4 mi
- Drive from Indianapolis to Spartanburgcar 493.4 mi
9h 32m$91–131Fly Evansville to Charlotte Douglas International Airport, train
- Fly from Evansville (EVV) to Charlotte Douglas International Airport (CLT)plane EVV - CLT
- Take the train from Charlotte Amtrak Station to Spartanburg Stationtrain
5h 39m$118–554Fly Fort Wayne International Airport to Charlotte Douglas International Airport, train
- Fly from Fort Wayne International Airport (FWA) to Charlotte Douglas International Airport (CLT)plane FWA - CLT
- Take the train from Charlotte Amtrak Station to Spartanburg Stationtrain
5h 57m$141–595Fly Indianapolis to Charlotte Douglas International Airport, train
- Fly from Indianapolis (IND) to Charlotte Douglas International Airport (CLT)plane IND - CLT
- Take the train from Charlotte Amtrak Station to Spartanburg Stationtrain
7h 5m$121–653Bus
- Take the bus from Indianapolis Union Station to Wilson & Ferrell Shell Station - Columbusbus
- Take the bus from Columbus to Charlottebus
- Take the bus from Charlotte Bus Station to Spartanburgbus
18h 15m$94–186
Indiana to Spartanburg by train (Amtrak)
Questions & Answers
The cheapest way to get from Indiana to Spartanburg is to drive which costs $90 - $130 and takes 9h 32m.
The fastest way to get from Indiana to Spartanburg is to train and fly which takes 5h 13m and costs $150 - $650.
No, there is no direct bus from Indiana to Spartanburg. However, there are services departing from Indianapolis and arriving at Servicios Zapata - Spartanburg via Atlanta. The journey, including transfers, takes approximately 17h 4m.
No, there is no direct train from Indiana to Spartanburg station. However, there are services departing from Indianapolis and arriving at Spartanburg Station via Charlottesville. The journey, including transfers, takes approximately 23h 49m.
The distance between Indiana and Spartanburg is 649 miles. The road distance is 496.3 miles.
The best way to get from Indiana to Spartanburg without a car is to bus via Atlanta which takes 17h 4m and costs $130 - $210.
It takes approximately 5h 13m to get from Indiana to Spartanburg, including transfers.
Indiana to Spartanburg bus services, operated by Flixbus USA, depart from Indianapolis station.
Indiana to Spartanburg train services, operated by Amtrak, depart from Indianapolis station.
The best way to get from Indiana to Spartanburg is to bus via Atlanta which takes 17h 4m and costs $130 - $210. Alternatively, you can train, which costs $240 - $600 and takes 23h 49m.
What companies run services between Indiana, USA and Spartanburg, SC, USA?
You can take a bus from Indianapolis to Spartanburg via Atlanta Bus Station, Garnett Station, Doraville Station, Atlanta, and Servicios Zapata - Spartanburg in around 17h 4m. Alternatively, you can take a train from Indianapolis to Spartanburg Station via Charlottesville in around 23h 49m.
- Website
- aa.com
Flights from Chicago O'Hare International Airport to Greenville–Spartanburg International Airport
- Ave. Duration
- 2h 1m
- When
- Every day
- Estimated price
- $90–550
Flights from Chicago O'Hare International Airport to Greenville–Spartanburg International Airport via Charlotte Douglas International Airport
- Ave. Duration
- 4h 13m
- When
- Every day
- Estimated price
- $100–550
Flights from Chicago O'Hare International Airport to Asheville Regional Airport
- Ave. Duration
- 1h 57m
- When
- Every day
- Estimated price
- $55–330
Flights from Chicago O'Hare International Airport to Asheville Regional Airport via Charlotte Douglas International Airport
- Ave. Duration
- 4h 6m
- When
- Every day
- Estimated price
- $65–360
Flights from Evansville to Charlotte Douglas International Airport
- Ave. Duration
- 1h 49m
- When
- Every day
- Estimated price
- $75–480
Flights from Fort Wayne International Airport to Charlotte Douglas International Airport
- Ave. Duration
- 1h 55m
- When
- Every day
- Estimated price
- $80–500
Flights from Indianapolis to Charlotte Douglas International Airport
- Ave. Duration
- 1h 43m
- When
- Every day
- Estimated price
- $95–600
- Phone
- +1 219-926-5744
- Website
- mysouthshoreline.com
Train from Gary to Van Buren St.
- Ave. Duration
- 52 min
- Frequency
- Hourly
- Estimated price
- $7–9
- Schedules at
- mysouthshoreline.com
- Adults 14-64
- $7–9
Train from Gary to Van Buren St.
- Ave. Duration
- 52 min
- Frequency
- Hourly
- Estimated price
- $7–9
- Schedules at
- mysouthshoreline.com
- Adults 14-64
- $7–9
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Indianapolis to Atlanta Bus Station
- Ave. Duration
- 11h 5m
- Frequency
- Twice daily
- Estimated price
- $80–140
- Schedules at
- Flixbus USA
Bus from Charlotte Bus Station to Spartanburg
- Ave. Duration
- 1h 20m
- Frequency
- Once daily
- Estimated price
- $9–16
- Schedules at
- Flixbus USA
Want to know more about travelling around United States
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More Questions & Answers
Indiana to Spartanburg bus services, operated by Flixbus USA, arrive at Atlanta Bus Station.
Indiana to Spartanburg train services, operated by Amtrak, arrive at Charlottesville station.
Yes, the driving distance between Indiana to Spartanburg is 496 miles. It takes approximately 9h 32m to drive from Indiana to Spartanburg.
Book your Indiana to Spartanburg train tickets online with Omio.
There are 84+ hotels available in Spartanburg.

