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How to get fromIndiana to Syracuseby plane, bus, train, bus (Greyhound), car, or train (Amtrak)

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There are 10 ways to get from Indiana to Syracuse by plane, bus, train, bus (Greyhound), car, or train (Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Indianapolis to Syracuse Hancock International Airport

    best
    1. Fly from Indianapolis (IND) to Syracuse Hancock International Airport (SYR)plane plane IND - SYR
    7h 27m
    $153–860

  2. Bus

    cheapest
    1. Take the bus from Indianapolis, IN to Toledobus bus
    2. Take the bus from Toledo Bus Stop to Cleveland Bus Stationbus bus
    3. Take the bus from Cleveland Bus Station to Syracuse Bus Stationbus bus
    14h 30m
    $87–199

  3. Bus, train

    1. Take the bus from Indianapolis, IN to Toledobus bus Cincinnati
    2. Take the train from Toledo to Syracuse Regional Transportation Centertrain train Lake Shore Limited
    12h 52m
    $152–350

  4. Drive 639.3 mi

    1. Drive from Indianapolis to Syracusecar car 639.3 mi
    11h 6m
    $117–169

  5. Train to Chicago O'Hare International Airport, fly to Syracuse Hancock International Airport

    1. Take the train from Gary to Van Buren St.train train
    2. Fly from Chicago O'Hare International Airport (ORD) to Syracuse Hancock International Airport (SYR)plane plane ORD - SYR
    6h 30m
    $131–671

  6. Train to South Bend, fly to Syracuse Hancock International Airport

    1. Take the train from Gary to South Bend Airporttrain train
    2. Fly from South Bend (SBN) to Syracuse Hancock International Airport (SYR)plane plane SBN - SYR
    7h 44m
    $141–769

  7. Train to Chicago Midway International Airport, fly to Rochester, train

    1. Take the train from Gary to Museum Campus/11th Street Sationtrain train
    2. Fly from Chicago Midway International Airport (MDW) to Rochester (ROC)plane plane MDW - ROC
    3. Take the train from Rochester to Syracuse Regional Transportation Centertrain train
    6h 33m
    $178–955

  8. Train to Chicago O'Hare International Airport, fly to Rochester, train

    1. Take the train from Gary to Van Buren St.train train
    2. Fly from Chicago O'Hare International Airport (ORD) to Rochester (ROC)plane plane ORD - ROC
    3. Take the train from Rochester to Syracuse Regional Transportation Centertrain train
    7h 3m
    $149–805

  9. Train to Chicago Midway International Airport, fly to Buffalo Niagara International Airport, bus

    1. Take the train from Gary to Museum Campus/11th Street Sationtrain train
    2. Fly from Chicago Midway International Airport (MDW) to Buffalo Niagara International Airport (BUF)plane plane MDW - BUF
    3. Take the bus from Buffalo Niagara International Airport to Syracuse Bus Stationbus bus
    7h 29m
    $196–473

  10. Train (Amtrak)

    1. Take the train from Indianapolis to Chicago Union Stationtrain train Cardinal
    2. Take the train from Chicago Union Station to Syracuse Regional Transportation Centertrain train Lake Shore Limited
    18h 58m
    $272–569

Indiana to Syracuse by bus and train

Calendar7Weekly Services
Duration12h 52mAverage Duration
Ticket$152Cheapest Price
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Questions & Answers

Map of how to get from Indiana to Syracuse.ExpandLaunch map view
  • Distance: 604.7 mi
  • Duration: 7h 27m

What companies run services between Indiana, USA and Syracuse, NY, USA?

United Airlines, Delta, and American Airlines fly from Indianapolis (IND) to Syracuse Hancock International Airport (SYR) hourly. Alternatively, you can take a bus from Indianapolis, IN to Syracuse Bus Station via Toledo Bus Stop and Cleveland Bus Station in around 14h 30m.

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