There are 9 ways to get from Indiana to Winston-Salem by train, plane, bus (Flixbus, Greyhound), car, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train to Chicago O'Hare International Airport, fly to Piedmont Triad International Airport
best- Take the train from Gary to Van Buren St.train
- Fly from Chicago O'Hare International Airport (ORD) to Piedmont Triad International Airport (GSO)plane ORD - GSO
5h 57m$139–636Drive 512 mi
cheapest- Drive from Indianapolis to Winston-Salemcar 512 mi
9h 6m$94–135Bus
- Take the bus from Indianapolis to Columbusbus FlixBus 2511 / ...
- Take the bus from Columbus to Winston Salem(Trans Center)bus Greyhound US0140
14h 14m$95–179Fly Evansville to Charlotte Douglas International Airport, bus
- Fly from Evansville (EVV) to Charlotte Douglas International Airport (CLT)plane EVV - CLT
- Take the bus from Charlotte Bus Station to Winston Salem(Trans Center)bus
5h 17m$110–559Fly Fort Wayne International Airport to Charlotte Douglas International Airport, bus
- Fly from Fort Wayne International Airport (FWA) to Charlotte Douglas International Airport (CLT)plane FWA - CLT
- Take the bus from Charlotte Bus Station to Winston Salem(Trans Center)bus
5h 33m$133–590Fly Indianapolis to Charlotte Douglas International Airport, bus
- Fly from Indianapolis (IND) to Charlotte Douglas International Airport (CLT)plane IND - CLT
- Take the bus from Charlotte Bus Station to Winston Salem(Trans Center)bus
6h 41m$113–698Train to South Bend, fly to Charlotte Douglas International Airport, bus
- Take the train from Gary to South Bend Airporttrain
- Fly from South Bend (SBN) to Charlotte Douglas International Airport (CLT)plane SBN - CLT
- Take the bus from Charlotte Bus Station to Winston Salem(Trans Center)bus
7h 25m$141–757Train to Chicago Midway International Airport, fly to Charlotte Douglas International Airport, bus
- Take the train from Gary to Museum Campus/11th Street Sationtrain
- Fly from Chicago Midway International Airport (MDW) to Charlotte Douglas International Airport (CLT)plane MDW - CLT
- Take the bus from Charlotte Bus Station to Winston Salem(Trans Center)bus
7h 42m$140–759Train, bus
- Take the train from Indianapolis to Ashland Amtrak Stationtrain Cardinal
- Take the bus from Ashland Bus Station to Winston Salem(Trans Center)bus Greyhound US0140
14h 35m$134–268
Indiana to Winston-Salem by bus
Questions & Answers
The cheapest way to get from Indiana to Winston-Salem is to drive which costs $90 - $140 and takes 9h 6m.
The fastest way to get from Indiana to Winston-Salem is to fly and bus which takes 5h 17m and costs $110 - $600.
No, there is no direct bus from Indiana to Winston-Salem. However, there are services departing from Indianapolis and arriving at Winston Salem(Trans Center) via E Main St & S High St and Columbus. The journey, including transfers, takes approximately 14h 14m.
The distance between Indiana and Winston-Salem is 664 miles. The road distance is 515 miles.
The best way to get from Indiana to Winston-Salem without a car is to bus which takes 14h 14m and costs $95 - $180.
It takes approximately 5h 57m to get from Indiana to Winston-Salem, including transfers.
Indiana to Winston-Salem bus services, operated by Flixbus USA, depart from Indianapolis station.
Indiana to Winston-Salem bus services, operated by Flixbus USA, arrive at Columbus station.
Yes, the driving distance between Indiana to Winston-Salem is 515 miles. It takes approximately 9h 6m to drive from Indiana to Winston-Salem.
Book your Indiana to Winston-Salem bus tickets online with FlixBus.
What companies run services between Indiana, USA and Winston-Salem, NC, USA?
You can take a bus from Indianapolis to Winston Salem(Trans Center) via Columbus, E Main St & S High St, S Grant Ave & E Mound St, and Columbus in around 14h 14m.
- Website
- aa.com
Flights from Chicago O'Hare International Airport to Piedmont Triad International Airport
- Ave. Duration
- 2h 2m
- When
- Every day
- Estimated price
- $110–600
Flights from Chicago O'Hare International Airport to Piedmont Triad International Airport via Charlotte Douglas International Airport
- Ave. Duration
- 4h 10m
- When
- Every day
- Estimated price
- $120–650
Flights from Evansville to Charlotte Douglas International Airport
- Ave. Duration
- 1h 52m
- When
- Every day
- Estimated price
- $80–490
Flights from Fort Wayne International Airport to Charlotte Douglas International Airport
- Ave. Duration
- 1h 55m
- When
- Every day
- Estimated price
- $85–500
Flights from Fort Wayne International Airport to Charlotte Douglas International Airport via Chicago O'Hare International Airport
- Ave. Duration
- 4h 33m
- When
- Every day
- Estimated price
- $120–600
Flights from Indianapolis to Charlotte Douglas International Airport
- Ave. Duration
- 1h 45m
- When
- Every day
- Estimated price
- $100–650
Flights from South Bend to Charlotte Douglas International Airport
- Ave. Duration
- 2h 1m
- When
- Every day
- Estimated price
- $120–700
- Website
- united.com
Flights from Chicago O'Hare International Airport to Piedmont Triad International Airport
- Ave. Duration
- 2h 5m
- When
- Every day
- Estimated price
- $110–600
Flights from Chicago O'Hare International Airport to Piedmont Triad International Airport via Washington Dulles
- Ave. Duration
- 4h 24m
- When
- Every day
- Estimated price
- $130–700
Flights from Fort Wayne International Airport to Charlotte Douglas International Airport via Chicago O'Hare International Airport
- Ave. Duration
- 4h 37m
- When
- Every day
- Estimated price
- $120–600
Flights from South Bend to Charlotte Douglas International Airport via Washington Dulles
- Ave. Duration
- 4h 29m
- When
- Every day
- Estimated price
- $160–800
Flights from South Bend to Charlotte Douglas International Airport via Chicago O'Hare International Airport
- Ave. Duration
- 4h 44m
- When
- Every day
- Estimated price
- $140–750
- Website
- delta.com
Flights from Chicago O'Hare International Airport to Piedmont Triad International Airport via Atlanta
- Ave. Duration
- 4h 26m
- When
- Every day
- Estimated price
- $140–700
Flights from Evansville to Charlotte Douglas International Airport via Atlanta
- Ave. Duration
- 4h 9m
- When
- Every day
- Estimated price
- $100–550
Flights from Fort Wayne International Airport to Charlotte Douglas International Airport via Detroit
- Ave. Duration
- 4h 7m
- When
- Every day
- Estimated price
- $100–550
Flights from Fort Wayne International Airport to Charlotte Douglas International Airport via Atlanta
- Ave. Duration
- 4h 11m
- When
- Every day
- Estimated price
- $110–600
Flights from Indianapolis to Charlotte Douglas International Airport via Atlanta
- Ave. Duration
- 4h
- When
- Every day
- Estimated price
- $130–700
Flights from Indianapolis to Charlotte Douglas International Airport via Detroit
- Ave. Duration
- 4h 20m
- When
- Every day
- Estimated price
- $140–750
Flights from South Bend to Charlotte Douglas International Airport via Detroit
- Ave. Duration
- 3h 57m
- When
- Every day
- Estimated price
- $130–750
Flights from South Bend to Charlotte Douglas International Airport via Atlanta
- Ave. Duration
- 4h 29m
- When
- Every day
- Estimated price
- $150–800
- Website
- southwest.com
Flights from Indianapolis to Charlotte Douglas International Airport via Nashville
- Ave. Duration
- 3h 51m
- When
- Every day
- Estimated price
- $120–700
Flights from Indianapolis to Charlotte Douglas International Airport via Chicago Midway International Airport
- Ave. Duration
- 4h 5m
- When
- Saturday, Tuesday, and Wednesday
- Estimated price
- $140–750
Flights from Chicago Midway International Airport to Charlotte Douglas International Airport
- Ave. Duration
- 2h 2m
- When
- Every day
- Estimated price
- $120–700
- Phone
- +1 219-926-5744
- Website
- mysouthshoreline.com
Train from Gary to Van Buren St.
- Ave. Duration
- 52 min
- Frequency
- Hourly
- Estimated price
- $7–9
- Schedules at
- mysouthshoreline.com
- Adults 14-64
- $7–9
Train from Gary to South Bend Airport
- Ave. Duration
- 1h 13m
- Frequency
- Every 2 hours
- Estimated price
- $10–12
- Schedules at
- mysouthshoreline.com
- Adults 14-64
- $10–12
Train from Gary to Museum Campus/11th Street Sation
- Ave. Duration
- 49 min
- Frequency
- Hourly
- Estimated price
- $7–8
- Schedules at
- mysouthshoreline.com
- Adults 14-64
- $7–8
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Indianapolis to Ashland Amtrak Station
- Ave. Duration
- 6h 30m
- Frequency
- 3 times a week
- Estimated price
- $85–180
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 (855) 626-8585
- Website
- https://www.flixbus.com
Bus from Indianapolis to Columbus
- Ave. Duration
- 3h 30m
- Frequency
- Twice daily
- Estimated price
- $28–50
- Schedules at
- flixbus.com
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- greyhound.com
Bus from Columbus to Winston Salem(Trans Center)
- Ave. Duration
- 9h 20m
- Frequency
- Once daily
- Estimated price
- $65–130
- Website
- https://www.greyhound.com/
Bus from Charlotte Bus Station to Winston Salem(Trans Center)
- Ave. Duration
- 1h 25m
- Frequency
- Twice daily
- Estimated price
- $12–23
- Website
- https://www.greyhound.com/
Bus from Charlotte Bus Station to Winston Salem(Trans Center)
- Ave. Duration
- 1h 25m
- Frequency
- Twice daily
- Estimated price
- $12–23
- Website
- https://www.greyhound.com/
Bus from Charlotte Bus Station to Winston Salem(Trans Center)
- Ave. Duration
- 1h 25m
- Frequency
- Twice daily
- Estimated price
- $12–23
- Website
- https://www.greyhound.com/
Bus from Charlotte Bus Station to Winston Salem(Trans Center)
- Ave. Duration
- 1h 25m
- Frequency
- Twice daily
- Estimated price
- $12–23
- Website
- https://www.greyhound.com/
Bus from Charlotte Bus Station to Winston Salem(Trans Center)
- Ave. Duration
- 1h 25m
- Frequency
- Twice daily
- Estimated price
- $12–23
- Website
- https://www.greyhound.com/
Bus from Ashland Bus Station to Winston Salem(Trans Center)
- Ave. Duration
- 7h 5m
- Frequency
- Once daily
- Estimated price
- $45–90
- Website
- https://www.greyhound.com/
- Phone
- +1 888-378-3823
- [email protected]
- Website
- baronsbus.com
Bus from Charlotte Bus Station to Winston Salem(Trans Center)
- Ave. Duration
- 1h 15m
- Frequency
- Once daily
- Estimated price
- $7–40
- Website
- https://baronsbus.com
Bus from Charlotte Bus Station to Winston Salem(Trans Center)
- Ave. Duration
- 1h 15m
- Frequency
- Once daily
- Estimated price
- $7–40
- Website
- https://baronsbus.com
Bus from Charlotte Bus Station to Winston Salem(Trans Center)
- Ave. Duration
- 1h 15m
- Frequency
- Once daily
- Estimated price
- $7–40
- Website
- https://baronsbus.com
Bus from Charlotte Bus Station to Winston Salem(Trans Center)
- Ave. Duration
- 1h 15m
- Frequency
- Once daily
- Estimated price
- $7–40
- Website
- https://baronsbus.com
Bus from Charlotte Bus Station to Winston Salem(Trans Center)
- Ave. Duration
- 1h 15m
- Frequency
- Once daily
- Estimated price
- $7–40
- Website
- https://baronsbus.com
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide
Why you should take the train in the US
Read the travel guide
More Questions & Answers
There are 137+ hotels available in Winston-Salem.










