Rome2Rio

How to get fromIndianapolis, IN to Knoxvilleby plane, bus (Flixbus), train, bus, or car

Find Transport to Knoxville

See all options

There are 6 ways to get from Indianapolis, IN to Knoxville by plane, bus (Flixbus), train, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Mcghee Tyson Airport

    best
    1. Fly from Indianapolis (IND) to Mcghee Tyson Airport (TYS)plane plane IND - TYS
    4h 47m
    $185–838

  2. Drive 346.8 mi

    cheapest
    1. Drive from Indianapolis, IN to Knoxvillecar car 346.8 mi
    5h 58m
    $64–92

  3. Bus

    1. Take the bus from Indianapolis to New York City Chinatownbus bus FlixBus N2640
    2. Take the bus from New York, NY to Knoxville, TNbus bus Ny
    34h 1m
    $233–336

  4. Train, bus via Farragut

    1. Take the train from Indianapolis to Ny Moynihan Train Hall At Penn Stationtrain train Cardinal
    2. Take the bus from New York to Knoxvillebus bus Nyc
    35h 41m
    $491–874

  5. Fly to Nashville, drive

    1. Fly from Indianapolis (IND) to Nashville (BNA)plane plane IND - BNA
    2. Drive from Nashville-Airport-BNA to Knoxvillecar car
    5h 19m
    $350–1,168

  6. Train, bus

    1. Take the train from Indianapolis to Ny Moynihan Train Hall At Penn Stationtrain train Cardinal
    2. Take the bus from New York, NY to Knoxville, TNbus bus Ny
    35h 45m
    $446–784

Indianapolis (IND) to Mcghee Tyson Airport (TYS) flights

Calendar144Weekly Planes
Duration4h 44mAverage Duration
Ticket$120Cheapest Price
See schedules

Questions & Answers

Map of how to get from Indianapolis, IN to Knoxville.ExpandLaunch map view
  • Distance: 323.9 mi
  • Duration: 4h 47m

What companies run services between Indianapolis, IN, USA and Knoxville, TN, USA?

Southwest Airlines, Delta, and two other airlines fly from Indianapolis (IND) to Mcghee Tyson Airport (TYS) hourly. Alternatively, you can take a vehicle from Indianapolis, IN to Knoxville Station Hall of Fame via Indianapolis, New York, NY, Knoxville, TN, Walmart, and Charlie Haun WB Aft Washington PK in around 34h 1m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

More Questions & Answers