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How to get fromIndianapolis to Cape Girardeauby bus, train, taxi, car, plane, or bus (Greyhound)

Find Transport to Cape Girardeau

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There are 7 ways to get from Indianapolis to Cape Girardeau by bus, train, taxi, car, plane, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus, train, taxi

    best
    1. Take the bus from Indianapolis Union Station to Champaign Intermodal Trans Ctrbus bus
    2. Take the train from Champaign-Urbana to Carbondaletrain train
    3. Take the taxi from Carbondale to Cape Girardeautaxi taxi
    6h 59m
    $217–322

  2. Drive  304.2 mi

    cheapest
    1. Drive from Indianapolis to Cape Girardeaucar car 304.2 mi
    5h 10m
    $52–76

  3. Fly Indianapolis to Williamson County Regional Airport, taxi

    1. Fly from Indianapolis (IND) to Williamson County Regional Airport (MWA)plane plane IND - MWA
    2. Take the taxi from Williamson County Regional Airport (MWA) to Cape Girardeautaxi taxi
    6h 42m
    $202–592

  4. Bus (Greyhound)

    1. Take the bus from Indianapolis Union Station to St Louis Bus Stationbus bus Greyhound US0421
    2. Take the bus from St Louis Bus Station to Cape Girardeaubus bus Greyhound US1173
    7h 4m
    $71–109

  5. Fly Indianapolis to Barkley Regional Airport, taxi

    1. Fly from Indianapolis (IND) to Barkley Regional Airport (PAH)plane plane IND - PAH
    2. Take the taxi from Barkley Regional Airport (PAH) to Cape Girardeautaxi taxi
    7h 10m
    $217–612

  6. Bus, train to Chicago O'Hare International Airport, fly to Cape Girardeau Municipal Airport

    1. Take the bus from Indianapolis to Gary Bus Stationbus bus
    2. Take the train from Gary to Van Buren St.train train
    3. Fly from Chicago O'Hare International Airport (ORD) to Cape Girardeau Municipal Airport (CGI)plane plane ORD - CGI
    7h 47m
    $168–430

  7. Fly Indianapolis to Cape Girardeau Municipal Airport

    1. Fly from Indianapolis (IND) to Cape Girardeau Municipal Airport (CGI)plane plane IND - CGI
    6h 38m
    $145–630

Indianapolis (IND) to Williamson County Regional Airport (MWA) flights

Calendar24Weekly Planes
Duration4h 50mAverage Duration
Ticket$72Cheapest Price
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Comparing Your Travel Options

Map of how to get from Indianapolis to Cape Girardeau.ExpandLaunch map view
  • Distance: 346.4 mi
  • Duration: 6h 59m

What companies run services between Indianapolis, IN, USA and Cape Girardeau, MO, USA?

You can take a bus from Indianapolis Union Station to Cape Girardeau via St Louis Bus Station and Cape Girardeau in around 7h 4m. Alternatively, United Airlines, Corporate Flight Management Inc, and two other airlines fly from Indianapolis (IND) to Cape Girardeau Municipal Airport (CGI) twice daily.

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