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How to get fromIndianapolis to Charlestonby plane, bus (Greyhound), train (Amtrak), car, or bus

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There are 7 ways to get from Indianapolis to Charleston by plane, bus (Greyhound), train (Amtrak), car, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Indianapolis

    best
    1. Fly from Indianapolis (IND) to Charleston International Airport (CHS)plane plane IND - CHS
    6h 59m
    $94–484

  2. Bus

    1. Take the bus from Indianapolis to Atlanta Bus Stationbus bus FlixBus 2512
    2. Take the bus from Atlanta Bus Station to Charleston Bus Stationbus bus Greyhound US0641S
    24h 4m

  3. Train (Amtrak)

    1. Take the train from Indianapolis to Alexandriatrain train Cardinal
    2. Take the train from Alexandria to Charleston Amtrak Stationtrain train Silver Meteor / ...
    28h 28m
    $422–839

  4. Drive 693.3 mi

    1. Drive from Indianapolis to Charlestoncar car 693.3 mi
    12h 46m
    $127–183

  5. Bus to Covington, fly

    1. Take the bus from Indianapolis to Cincinnatibus bus
    2. Fly from Covington (CVG) to Charleston International Airport (CHS)plane plane CVG - CHS
    7h 32m

  6. Bus to Louisville International Airport, fly

    1. Take the bus from Indianapolis Union Station to Louisville Bus Stationbus bus
    2. Fly from Louisville International Airport (SDF) to Charleston International Airport (CHS)plane plane SDF - CHS
    7h 55m
    $367–452

  7. Bus via Indianapolis, Illinois St (Greyhound Bus Station)

    1. Take the bus from Indianapolis Union Station to Atlanta Bus Stationbus bus Greyhound US0100
    2. Take the bus from Atlanta Bus Station to Charleston Bus Stationbus bus Greyhound US0641S
    25h 34m
    $156–299

Indianapolis (IND) to Charleston International Airport (CHS) flights

Calendar98Weekly Planes
Duration4h 47mAverage Duration
Ticket$92Cheapest Price
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Questions & Answers

Map of how to get from Indianapolis to Charleston.ExpandLaunch map view
  • Distance: 616.4 mi
  • Duration: 6h 59m

What companies run services between Indianapolis, IN, USA and Charleston, SC, USA?

American Airlines, Delta, and two other airlines fly from Indianapolis (IND) to Charleston International Airport (CHS) hourly. Alternatively, you can take a bus from Indianapolis to Transit Mall via Atlanta Bus Station, Charleston Bus Station, North Charleston Transit Center, N. Charleston SuperStop, and Rivers Ave / Cosgrove Ave in around 24h 4m.

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