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How to get fromIndianapolis to Chicago Loopby bus (Amtrak, Greyhound), train (Amtrak), car, plane, bus (Greyhound), bus (Flixbus), subway, bus, or train

Find Transport to Chicago Loop

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There are 9 ways to get from Indianapolis to Chicago Loop by bus (Amtrak, Greyhound), train (Amtrak), car, plane, bus (Greyhound), bus (Flixbus), subway, bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from Indianapolis Union Station to Chicago Union Stationbus bus Nashville
    3h 40m
    $29–50

  2. Train (Amtrak)

    1. Take the train from Indianapolis to Chicago Union Stationtrain train Cardinal
    5h
    $45–120

  3. Drive  180.4 mi

    1. Drive from Indianapolis to Chicago Loopcar car 180.4 mi
    3h 12m
    $33–48

  4. Fly Indianapolis to Chicago O'Hare International Airport

    1. Fly from Indianapolis (IND) to Chicago O'Hare International Airport (ORD)plane plane IND - ORD
    3h 43m
    $424–907

  5. Bus via Washington & Lasalle (Greyhound)

    1. Take the bus from Indianapolis Union Station to Chicago Bus Stationbus bus Greyhound US0100 / ...
    3h 47m
    $32–48

  6. Bus via Indianapolis (Flixbus)

    1. Take the bus from Indianapolis to Chicago Bus Stationbus bus FlixBus 2511 / ...
    3h 52m
    $31–44

  7. Fly Indianapolis to Chicago Midway International Airport, subway

    1. Fly from Indianapolis (IND) to Chicago Midway International Airport (MDW)plane plane IND - MDW
    2. Take the subway from Midway to Washington/Wellssubway subway
    3h 30m
    $49–357

  8. Bus to Fort Wayne International Airport, fly to Chicago O'Hare International Airport

    1. Take the bus from Indianapolis, IN to Fort Wayne, INbus bus
    2. Fly from Fort Wayne International Airport (FWA) to Chicago O'Hare International Airport (ORD)plane plane FWA - ORD
    5h 20m
    $69–311

  9. Train to Purdue University Airport, fly to Chicago O'Hare International Airport

    1. Take the train from Indianapolis to Lafayette Amtrak Stationtrain train
    2. Fly from Purdue University Airport (LAF) to Chicago O'Hare International Airport (ORD)plane plane LAF - ORD
    5h 19m
    $49–269

Indianapolis to Chicago Loop by bus

Calendar28Weekly Buses
Duration3h 40mAverage Duration
Ticket$29Cheapest Price
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Comparing Your Travel Options

Map of how to get from Indianapolis to Chicago Loop.ExpandLaunch map view
  • Distance: 184.9 mi
  • Duration: 3h 40m

What companies run services between Indianapolis, IN, USA and Chicago Loop, IL, USA?

Amtrak Thruway operates a bus from Indianapolis Union Station to Chicago Union Station twice daily. Tickets cost $35–50 and the journey takes 3h 40m. Greyhound USA also services this route twice daily. Alternatively, Amtrak operates a train from Indianapolis to Chicago Union Station 3 times a week. Tickets cost $45–120 and the journey takes 5h.

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