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How to get fromIndianapolis to Chicago OTCby bus (Amtrak, Greyhound), train (Amtrak), car, plane, subway, bus (Flixbus, Greyhound), train, or bus

Find Transport to Chicago OTC

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There are 8 ways to get from Indianapolis to Chicago OTC by bus (Amtrak, Greyhound), train (Amtrak), car, plane, subway, bus (Flixbus, Greyhound), train, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from Indianapolis Union Station to Chicago Union Stationbus bus
    3h 45m
    $29–55

  2. Bus via Indianapolis

    cheapest
    1. Take the bus from Indianapolis to Chicago Bus Stationbus bus FlixBus 2511 / ...
    3h 52m
    $28–55

  3. Train (Amtrak)

    1. Take the train from Indianapolis to Chicago Union Stationtrain train Cardinal
    5h 5m
    $65–130

  4. Drive 180.3 mi

    1. Drive from Indianapolis to Chicago OTCcar car 180.3 mi
    3h 12m
    $33–48

  5. Fly Indianapolis to Chicago Midway International Airport, subway

    1. Fly from Indianapolis (IND) to Chicago Midway International Airport (MDW)plane plane IND - MDW
    2. Take the subway from Midway to Washington/Wellssubway subway
    3h 38m
    $49–327

  6. Fly Indianapolis to Chicago O'Hare International Airport

    1. Fly from Indianapolis (IND) to Chicago O'Hare International Airport (ORD)plane plane IND - ORD
    4h 2m
    $424–1,307

  7. Train to Purdue University Airport, fly to Chicago O'Hare International Airport

    1. Take the train from Indianapolis to Lafayette Amtrak Stationtrain train
    2. Fly from Purdue University Airport (LAF) to Chicago O'Hare International Airport (ORD)plane plane LAF - ORD
    5h 28m
    $56–265

  8. Bus to Fort Wayne International Airport, fly to Chicago O'Hare International Airport

    1. Take the bus from Indianapolis, IN to Fort Wayne, INbus bus
    2. Fly from Fort Wayne International Airport (FWA) to Chicago O'Hare International Airport (ORD)plane plane FWA - ORD
    5h 32m
    $69–301

Indianapolis to Chicago OTC by bus and foot

Calendar28Weekly Services
Duration3h 45mAverage Duration
Ticket$29Cheapest Price
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Questions & Answers

Map of how to get from Indianapolis to Chicago OTC.ExpandLaunch map view
  • Distance: 185.2 mi
  • Duration: 3h 45m

What companies run services between Indianapolis, IN, USA and Chicago OTC, IL, USA?

Amtrak Thruway operates a bus from Indianapolis Union Station to Chicago Union Station twice daily. Tickets cost $35–50 and the journey takes 3h 40m. Greyhound USA also services this route twice daily. Alternatively, Amtrak operates a train from Indianapolis to Chicago Union Station 3 times a week. Tickets cost $65–130 and the journey takes 5h.

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