There are 5 ways to get from Indianapolis to Cleveland Clinic by bus, car, plane, train, or bus (Flixbus)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus
best- Take the bus from Indianapolis to Toledobus Bsb 14
- Take the bus from Toledo to Clevelandbus Bsb 26
7h 25m$36–108Drive 313.4 mi
- Drive from Indianapolis to Cleveland Cliniccar 313.4 mi
5h 31m$58–83Fly
- Fly from Indianapolis (IND) to Cleveland-Hopkins International Airport (CLE)plane IND - CLE
6h 7m$315–955Bus, train
- Take the bus from Indianapolis to Toledobus Bsb 14
- Take the train from Toledo to Cleveland Amtraktrain Floridian / ...
7h 52m$80–158Bus via Columbus
- Take the bus from Indianapolis to Columbusbus FlixBus 2511 / ...
- Take the bus from Columbus, Ohio Greyhound Station to Cleveland Ohio Greyhound Stationbus 374 D
10h 18m$85–253
Indianapolis to Cleveland Clinic by bus and foot
Comparing Your Travel Options
The cheapest way to get from Indianapolis to Cleveland Clinic is to bus which costs $35 - $110 and takes 7h 25m.
The fastest way to get from Indianapolis to Cleveland Clinic is to drive which takes 5h 31m and costs $55 - $85.
No, there is no direct bus from Indianapolis to Cleveland Clinic. However, there are services departing from Indianapolis and arriving at E 105Th St & Chester Av via Toledo and Superior Av & E 13Th St. The journey, including transfers, takes approximately 7h 25m.
The distance between Indianapolis and Cleveland Clinic is 340 miles. The road distance is 315.3 miles.
The best way to get from Indianapolis to Cleveland Clinic without a car is to bus which takes 7h 25m and costs $35 - $110.
It takes approximately 7h 25m to get from Indianapolis to Cleveland Clinic, including transfers.
Indianapolis to Cleveland Clinic bus services, operated by Barons Bus, depart from Indianapolis station.
The best way to get from Indianapolis to Cleveland Clinic is to bus which takes 7h 25m and costs $35 - $110. Alternatively, you can fly, which costs $310 - $1,000 and takes 6h 7m.
Indianapolis to Cleveland Clinic bus services, operated by Barons Bus, arrive at Toledo station.
Yes, the driving distance between Indianapolis to Cleveland Clinic is 315 miles. It takes approximately 5h 31m to drive from Indianapolis to Cleveland Clinic.
What companies run services between Indianapolis, IN, USA and Cleveland Clinic, OH, USA?
You can take a bus from Indianapolis to Cleveland Clinic via Toledo, Cleveland, Superior Av & E 13Th St, and E 105Th St & Chester Av in around 7h 25m. Alternatively, Delta, Southwest Airlines, and three other airlines fly from Indianapolis (IND) to Cleveland-Hopkins International Airport (CLE) hourly.
- Website
- united.com
Flights from Indianapolis to Cleveland-Hopkins International Airport via Chicago O'Hare
- Ave. Duration
- 4h 9m
- When
- Every day
- Estimated price
- $90–600
Flights from Indianapolis to Cleveland-Hopkins International Airport via Toronto
- Ave. Duration
- 4h 4m
- When
- Every day
- Estimated price
- $100–600
Flights from Indianapolis to Cleveland-Hopkins International Airport via Washington Dulles
- Ave. Duration
- 4h 12m
- When
- Every day
- Estimated price
- $120–650
- Website
- southwest.com
Flights from Indianapolis to Cleveland-Hopkins International Airport via Chicago Midway
- Ave. Duration
- 3h 22m
- When
- Every day
- Estimated price
- $90–550
Flights from Indianapolis to Cleveland-Hopkins International Airport via Baltimore
- Ave. Duration
- 4h 3m
- When
- Tuesday, Wednesday, and Saturday
- Estimated price
- $120–700
Flights from Indianapolis to Cleveland-Hopkins International Airport via Nashville
- Ave. Duration
- 4h 40m
- When
- Tuesday and Wednesday
- Estimated price
- $110–650
- Website
- delta.com
Flights from Indianapolis to Cleveland-Hopkins International Airport via Detroit
- Ave. Duration
- 3h 44m
- When
- Every day
- Estimated price
- $75–550
- Website
- aircanada.com
Flights from Indianapolis to Cleveland-Hopkins International Airport via Toronto
- Ave. Duration
- 4h 4m
- When
- Every day
- Estimated price
- $100–600
- Website
- aa.com
Flights from Indianapolis to Cleveland-Hopkins International Airport via Chicago O'Hare
- Ave. Duration
- 4h 28m
- When
- Every day
- Estimated price
- $90–600
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Toledo to Cleveland Amtrak
- Ave. Duration
- 1h 56m
- Frequency
- 3 times a day
- Estimated price
- $55–95
- Website
- Amtrak
- Phone
- +1 888-378-3823
- [email protected]
- Website
- Barons Bus
Bus from Indianapolis to Toledo
- Ave. Duration
- 3h 55m
- Frequency
- Once daily
- Estimated price
- $21–65
- Website
- Barons Bus
Bus from Toledo to Cleveland
- Ave. Duration
- 1h 45m
- Frequency
- Once daily
- Estimated price
- $11–45
- Website
- Barons Bus
Bus from Indianapolis to Toledo
- Ave. Duration
- 3h 55m
- Frequency
- Once daily
- Estimated price
- $21–65
- Website
- Barons Bus
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Indianapolis to Columbus
- Ave. Duration
- 3h 30m
- Frequency
- Twice daily
- Estimated price
- $26–40
- Schedules at
- Flixbus USA
- Phone
- +1 502-368-5644 x 135
- Website
- Miller Transportation
Bus from Columbus, Ohio Greyhound Station to Cleveland Ohio Greyhound Station
- Ave. Duration
- 5h
- Frequency
- Once daily
- Estimated price
- $55–210
- Website
- Miller Transportation
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Booking & Getting There
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