There are 4 ways to get from Indianapolis to Des Moines by plane, bus (Greyhound), car, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Indianapolis
best- Fly from Indianapolis (IND) to Des Moines (DSM)plane IND - DSM
5h 22m$129–723Bus (Greyhound)
cheapest- Take the bus from Indianapolis Union Station to Des Moinesbus Greyhound US0157S
9h 55m$70–140Drive 466.6 mi
- Drive from Indianapolis to Des Moinescar 466.6 mi
7h 55m$86–123Train to Purdue University Airport, fly
- Take the train from Indianapolis to Lafayette Amtrak Stationtrain
- Fly from Purdue University Airport (LAF) to Des Moines (DSM)plane LAF - DSM
7h 44m$133–621
Indianapolis to Des Moines by bus (Greyhound)
Questions & Answers
The cheapest way to get from Indianapolis to Des Moines is to bus which costs $70 - $140 and takes 9h 55m.
The fastest way to get from Indianapolis to Des Moines is to fly which takes 5h 22m and costs $120 - $750.
Yes, there is a direct bus departing from Indianapolis Union Station station and arriving at Des Moines. Services depart once daily, and operate every day. The journey takes approximately 9h 55m.
The distance between Indianapolis and Des Moines is 430 miles. The road distance is 469.3 miles.
The best way to get from Indianapolis to Des Moines without a car is to bus which takes 9h 55m and costs $70 - $140.
It takes approximately 5h 22m to get from Indianapolis to Des Moines, including transfers.
Indianapolis to Des Moines bus services, operated by Greyhound USA, depart from Indianapolis Union Station.
The best way to get from Indianapolis to Des Moines is to fly which takes 5h 22m and costs $120 - $750. Alternatively, you can bus, which costs $70 - $140 and takes 9h 55m.
Indianapolis to Des Moines bus services, operated by Greyhound USA, arrive at Des Moines station.
Des Moines is 1h behind Indianapolis. It is currently 10:19 PM in Indianapolis and 9:19 PM in Des Moines.
What companies run services between Indianapolis, IN, USA and Des Moines, IA, USA?
Southwest Airlines, United Airlines, and two other airlines fly from Indianapolis (IND) to Des Moines (DSM) hourly. Alternatively, Greyhound USA operates a bus from Indianapolis Union Station to Des Moines once daily. Tickets cost $70–140 and the journey takes 9h 55m.
- Website
- united.com
Flights from Indianapolis to Des Moines via Chicago O'Hare
- Ave. Duration
- 4h 31m
- When
- Every day
- Estimated price
- $120–700
Flights from Purdue University Airport to Des Moines via Chicago O'Hare
- Ave. Duration
- 4h 57m
- When
- Monday, Friday, Sunday, and Thursday
- Estimated price
- $90–550
- Website
- delta.com
Flights from Indianapolis to Des Moines via Detroit
- Ave. Duration
- 4h 10m
- When
- Every day
- Estimated price
- $160–850
Flights from Indianapolis to Des Moines via Minneapolis
- Ave. Duration
- 5h 7m
- When
- Every day
- Estimated price
- $150–800
Flights from Indianapolis to Des Moines via Atlanta
- Ave. Duration
- 4h 50m
- When
- Every day
- Estimated price
- $210–1,000
- Website
- aa.com
Flights from Indianapolis to Des Moines via Chicago O'Hare
- Ave. Duration
- 5h 29m
- When
- Every day
- Estimated price
- $120–700
Flights from Indianapolis to Des Moines via Charlotte
- Ave. Duration
- 7h 8m
- When
- Every day
- Estimated price
- $220–1,100
- Website
- southwest.com
Flights from Indianapolis to Des Moines via Chicago Midway
- Ave. Duration
- 4h 55m
- When
- Tuesday to Saturday
- Estimated price
- $110–700
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Indianapolis to Lafayette Amtrak Station
- Ave. Duration
- 1h 36m
- Frequency
- 3 times a week
- Estimated price
- $24–50
- Website
- https://www.amtrak.com/home.html
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- greyhound.com
Bus from Indianapolis Union Station to Des Moines
- Ave. Duration
- 9h 55m
- Frequency
- Once daily
- Estimated price
- $70–140
- Website
- https://www.greyhound.com/
Want to know more about travelling around United States
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More Questions & Answers
Yes, the driving distance between Indianapolis to Des Moines is 469 miles. It takes approximately 7h 55m to drive from Indianapolis to Des Moines.
Book your Indianapolis to Des Moines bus tickets online with Omio and FlixBus.
There are 263+ hotels available in Des Moines.