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How to get fromIndianapolis to Des Plainesby bus (Flixbus), train (Amtrak), car, plane, bus, or train

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There are 8 ways to get from Indianapolis to Des Plaines by bus (Flixbus), train (Amtrak), car, plane, bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus (Flixbus)

    best
    1. Take the bus from Indianapolis to Chicago Bus Stationbus bus FlixBus 2511 / ...
    5h 1m
    $37–56

  2. Drive 197.2 mi

    cheapest
    1. Drive from Indianapolis to Des Plainescar car 197.2 mi
    3h 36m
    $36–52

  3. Train (Amtrak)

    1. Take the train from Indianapolis to Chicago Union Stationtrain train Cardinal
    6h 10m
    $71–136

  4. Fly Indianapolis to Chicago O'Hare International Airport

    1. Fly from Indianapolis (IND) to Chicago O'Hare International Airport (ORD)plane plane IND - ORD
    3h 39m
    $423–1,357

  5. Bus via Lafayette

    1. Take the bus from Indianapolis Airport to Purdue Memorial Unionbus bus Indianapolis
    2. Take the bus from Purdue Memorial Union to O'Hare Multi-Modal Facilitybus bus Purdue
    6h 15m
    $85–117

  6. Fly Indianapolis to Chicago Midway International Airport, train

    1. Fly from Indianapolis (IND) to Chicago Midway International Airport (MDW)plane plane IND - MDW
    2. Take the train from Chicago OTC to Des Plainestrain train
    4h 42m
    $53–332

  7. Train to Purdue University Airport, fly to Chicago O'Hare International Airport

    1. Take the train from Indianapolis to Lafayette Amtrak Stationtrain train
    2. Fly from Purdue University Airport (LAF) to Chicago O'Hare International Airport (ORD)plane plane LAF - ORD
    5h 5m
    $54–315

  8. Bus to Fort Wayne International Airport, fly to Chicago O'Hare International Airport

    1. Take the bus from Indianapolis, IN to Fort Wayne, INbus bus
    2. Fly from Fort Wayne International Airport (FWA) to Chicago O'Hare International Airport (ORD)plane plane FWA - ORD
    5h 9m
    $68–357

Indianapolis to Des Plaines by bus, foot, and train (Flixbus)

Calendar41Weekly Services
Duration5h 1mAverage Duration
Ticket$37Cheapest Price
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Questions & Answers

Map of how to get from Indianapolis to Des Plaines.ExpandLaunch map view
  • Distance: 201.8 mi
  • Duration: 5h 1m

What companies run services between Indianapolis, IN, USA and Des Plaines, IL, USA?

Flixbus USA operates a bus from Indianapolis to Chicago Bus Station every 4 hours. Tickets cost $29–50 and the journey takes 3h 40m. Alternatively, Amtrak operates a train from Indianapolis to Chicago Union Station 3 times a week. Tickets cost $60–130 and the journey takes 5h.

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