There are 8 ways to get from Indianapolis to Duke University by plane, bus, bus (Flixbus, Greyhound), train (Amtrak), car, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Indianapolis to Raleigh-Durham International Airport, bus, line 700 bus
best- Fly from Indianapolis (IND) to Raleigh-Durham International Airport (RDU)plane IND - RDU
- Take the bus from RDU Airport at Terminal 2 to Regional Transit Centerbus
- Take the bus from Regional Transit Center to Duke St at Jackson Stbus
5h 40m$89–489Bus
- Take the bus from Indianapolis to Columbusbus
- Take the bus from Columbus to Winston Salem(Trans Center)bus
- Take the bus from Winston Salem(Trans Center) to Durhambus
17h 45m$108–203Train (Amtrak)
- Take the train from Indianapolis to Charlottesvilletrain
- Take the train from Charlottesville to Greensborotrain
- Take the train from Greensboro to Durham Amtrak Stationtrain
22h 26m$276–558Drive 587.3 mi
- Drive from Indianapolis to Duke Universitycar 587.3 mi
10h 26m$108–155Fly Indianapolis to Piedmont Triad International Airport, train
- Fly from Indianapolis (IND) to Piedmont Triad International Airport (GSO)plane IND - GSO
- Take the train from Greensboro to Durham Amtrak Stationtrain
8h 44m$170–778Bus to Covington, fly to Raleigh-Durham International Airport
- Take the bus from Indianapolis to Cincinnatibus
- Fly from Covington (CVG) to Raleigh-Durham International Airport (RDU)plane CVG - RDU
7h 55m$236–480Train, bus
- Take the train from Indianapolis to Ashland Amtrak Stationtrain
- Take the bus from Ashland Bus Station to Winston Salem(Trans Center)bus
- Take the bus from Coble Transportation Center to N Columbia St at W Franklin Stbus 4
19h 26m$143–275Train via Arlington (Amtrak)
- Take the train from Indianapolis to Alexandriatrain Cardinal
- Take the train from Alexandria to Durham Amtrak Stationtrain Carolinian
26h 20m$336–674
Indianapolis to Duke University by bus and foot
Questions & Answers
The cheapest way to get from Indianapolis to Duke University is to bus which costs $100 - $210 and takes 17h 45m.
The fastest way to get from Indianapolis to Duke University is to fly and bus and line 700 bus which takes 5h 40m and costs $85 - $490.
No, there is no direct bus from Indianapolis to Duke University. However, there are services departing from Indianapolis and arriving at Flowers Dr at Duke Gardens via E Main St & S 5Th St, Columbus, Winston Salem(Trans Center) and Durham Station. The journey, including transfers, takes approximately 17h 45m.
No, there is no direct train from Indianapolis to Duke University station. However, there are services departing from Indianapolis and arriving at Durham Amtrak Station via Charlottesville and Greensboro. The journey, including transfers, takes approximately 22h 26m.
The distance between Indianapolis and Duke University is 526 miles. The road distance is 590.8 miles.
The best way to get from Indianapolis to Duke University without a car is to bus which takes 17h 45m and costs $100 - $210.
It takes approximately 5h 40m to get from Indianapolis to Duke University, including transfers.
Indianapolis to Duke University bus services, operated by Flixbus USA, depart from Indianapolis station.
Indianapolis to Duke University train services, operated by Amtrak, depart from Indianapolis station.
The best way to get from Indianapolis to Duke University is to bus which takes 17h 45m and costs $100 - $210. Alternatively, you can train, which costs $270 - $600 and takes 22h 26m.
What companies run services between Indianapolis, IN, USA and Duke University, NC, USA?
You can take a bus from Indianapolis to Duke University via Columbus, E Main St & S 5Th St, S Grant Ave & E Mound St, Columbus, Winston Salem(Trans Center), Durham, Durham Station, and Flowers Dr at Duke Gardens in around 17h 45m. Alternatively, you can take a train from Indianapolis to Duke University via Charlottesville, Greensboro, Durham Amtrak Station, Durham Station, and Erwin Rd at Downing St in around 22h 26m.
- Website
- aa.com
Flights from Indianapolis to Raleigh-Durham International Airport via Charlotte
- Ave. Duration
- 3h 33m
- When
- Every day
- Estimated price
- $90–500
Flights from Indianapolis to Piedmont Triad International Airport via Charlotte
- Ave. Duration
- 5h 11m
- When
- Every day
- Estimated price
- $120–700
Flights from Indianapolis to Piedmont Triad International Airport via Philadelphia
- Ave. Duration
- 5h 26m
- When
- Every day
- Estimated price
- $180–900
Flights from Indianapolis to Piedmont Triad International Airport via Reagan Washington
- Ave. Duration
- 5h 4m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $150–800
Flights from Indianapolis to Piedmont Triad International Airport via Chicago O'Hare
- Ave. Duration
- 5h 41m
- When
- Every day
- Estimated price
- $150–800
Flights from Covington to Raleigh-Durham International Airport via Charlotte
- Ave. Duration
- 3h 27m
- When
- Every day
- Estimated price
- $85–490
- Website
- delta.com
Flights from Indianapolis to Raleigh-Durham International Airport
- Ave. Duration
- 1h 50m
- When
- Every day
- Estimated price
- $80–480
Flights from Indianapolis to Raleigh-Durham International Airport via Atlanta
- Ave. Duration
- 4h 2m
- When
- Every day
- Estimated price
- $110–600
Flights from Indianapolis to Raleigh-Durham International Airport via Detroit
- Ave. Duration
- 4h 2m
- When
- Every day
- Estimated price
- $100–550
Flights from Indianapolis to Piedmont Triad International Airport via Atlanta
- Ave. Duration
- 4h 47m
- When
- Every day
- Estimated price
- $150–800
Flights from Indianapolis to Piedmont Triad International Airport via Detroit
- Ave. Duration
- 4h 17m
- When
- Every day
- Estimated price
- $140–800
Flights from Covington to Raleigh-Durham International Airport
- Ave. Duration
- 1h 30m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $75–470
- Website
- southwest.com
Flights from Indianapolis to Raleigh-Durham International Airport via Nashville
- Ave. Duration
- 3h 40m
- When
- Monday to Wednesday
- Estimated price
- $100–550
Flights from Indianapolis to Raleigh-Durham International Airport via Baltimore
- Ave. Duration
- 3h 48m
- When
- Saturday, Tuesday, and Wednesday
- Estimated price
- $110–600
Flights from Indianapolis to Raleigh-Durham International Airport via Chicago Midway
- Ave. Duration
- 3h 51m
- When
- Saturday, Sunday, Tuesday, and Wednesday
- Estimated price
- $110–600
Flights from Covington to Raleigh-Durham International Airport via Nashville
- Ave. Duration
- 3h 40m
- When
- Saturday, Tuesday, and Wednesday
- Estimated price
- $100–600
Flights from Covington to Raleigh-Durham International Airport via Baltimore
- Ave. Duration
- 3h 40m
- When
- Monday, Thursday, and Friday
- Estimated price
- $100–600
- Website
- united.com
Flights from Indianapolis to Raleigh-Durham International Airport via Washington Dulles
- Ave. Duration
- 3h 57m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $100–550
Flights from Indianapolis to Piedmont Triad International Airport via Washington Dulles
- Ave. Duration
- 4h 14m
- When
- Every day
- Estimated price
- $150–800
Flights from Indianapolis to Piedmont Triad International Airport via Chicago O'Hare
- Ave. Duration
- 4h 39m
- When
- Every day
- Estimated price
- $150–800
Flights from Indianapolis to Piedmont Triad International Airport via Newark
- Ave. Duration
- 5h 25m
- When
- Every day
- Estimated price
- $200–950
Flights from Covington to Raleigh-Durham International Airport via Washington Dulles
- Ave. Duration
- 3h 54m
- When
- Every day
- Estimated price
- $100–550
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Indianapolis to Charlottesville
- Ave. Duration
- 15h 20m
- Frequency
- 3 times a week
- Estimated price
- $200–400
- Website
- https://www.amtrak.com/home.html
Train from Charlottesville to Greensboro
- Ave. Duration
- 3h 33m
- Frequency
- Once daily
- Estimated price
- $55–120
- Website
- https://www.amtrak.com/home.html
Train from Greensboro to Durham Amtrak Station
- Ave. Duration
- 1h 1m
- Frequency
- 5 times a day
- Estimated price
- $18–40
- Website
- https://www.amtrak.com/home.html
Train from Greensboro to Durham Amtrak Station
- Ave. Duration
- 1h 1m
- Frequency
- 5 times a day
- Estimated price
- $18–40
- Website
- https://www.amtrak.com/home.html
Train from Indianapolis to Ashland Amtrak Station
- Ave. Duration
- 6h 30m
- Frequency
- 3 times a week
- Estimated price
- $85–180
- Website
- https://www.amtrak.com/home.html
Train from Indianapolis to Alexandria
- Ave. Duration
- 18h 12m
- Frequency
- 3 times a week
- Estimated price
- $230–470
- Website
- https://www.amtrak.com/home.html
Train from Alexandria to Durham Amtrak Station
- Ave. Duration
- 6h 32m
- Frequency
- Once daily
- Estimated price
- $100–210
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 919 485 7433
- [email protected]
- Website
- gotriangle.org
Bus from RDU Airport at Terminal 2 to Regional Transit Center
- Ave. Duration
- 12 min
- Frequency
- Hourly
- Estimated price
- $3
- Website
- https://gotriangle.org/
- Regular one-way fare
- $3
Bus from Regional Transit Center to Duke St at Jackson St
- Ave. Duration
- 33 min
- Frequency
- Every 30 minutes
- Estimated price
- $3
- Website
- https://gotriangle.org/
- Phone
- +1 (855) 626-8585
- Website
- https://www.flixbus.com
Bus from Indianapolis to Columbus
- Ave. Duration
- 3h 30m
- Frequency
- Twice daily
- Estimated price
- $27–45
- Schedules at
- flixbus.com
Bus from Indianapolis to Cincinnati
- Ave. Duration
- 2h
- Frequency
- Twice daily
- Estimated price
- $17–28
- Schedules at
- flixbus.com
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- greyhound.com
Bus from Columbus to Winston Salem(Trans Center)
- Ave. Duration
- 9h 20m
- Frequency
- Once daily
- Estimated price
- $65–130
- Website
- https://www.greyhound.com/
Bus from Winston Salem(Trans Center) to Durham
- Ave. Duration
- 1h 50m
- Frequency
- Once daily
- Estimated price
- $12–24
- Website
- https://www.greyhound.com/
Bus from Ashland Bus Station to Winston Salem(Trans Center)
- Ave. Duration
- 7h 5m
- Frequency
- Once daily
- Estimated price
- $45–90
- Website
- https://www.greyhound.com/
- Phone
- +1 336-662-0002
- Website
- partnc.org
Bus from Coble Transportation Center to N Columbia St at W Franklin St
- Ave. Duration
- 1h 51m
- Frequency
- Twice daily
- Estimated price
- $3
- Website
- http://www.partnc.org
- Schedules at
- https://www.partnc.org/27/Routes-Schedules
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More Questions & Answers
Indianapolis to Duke University bus services, operated by Flixbus USA, arrive at Columbus station.
Indianapolis to Duke University train services, operated by Amtrak, arrive at Charlottesville station.
Yes, the driving distance between Indianapolis to Duke University is 591 miles. It takes approximately 10h 26m to drive from Indianapolis to Duke University.
There are 379+ hotels available in Duke University.









