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How to get fromIndianapolis to East Saint Louisby bus (Greyhound), train (Amtrak), car, plane, or train

Find Transport to East Saint Louis

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There are 5 ways to get from Indianapolis to East Saint Louis by bus (Greyhound), train (Amtrak), car, plane, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus (Greyhound)

    best
    1. Take the bus from Indianapolis Union Station to St Louis Bus Stationbus bus Greyhound US0421
    4h 11m
    $40–73

  2. Train (Amtrak)

    1. Take the train from Indianapolis to Chicago Union Stationtrain train Cardinal
    2. Take the train from Chicago Union Station to St. Louistrain train Lincoln Service / ...
    11h 2m
    $157–322

  3. Drive 239.5 mi

    1. Drive from Indianapolis to East Saint Louiscar car 239.5 mi
    3h 58m
    $44–64

  4. Fly from Indianapolis

    1. Fly from Indianapolis (IND) to Lambert–St. Louis International Airport (STL)plane plane IND - STL
    5h 52m
    $100–605

  5. Train to Purdue University Airport, fly

    1. Take the train from Indianapolis to Lafayette Amtrak Stationtrain train
    2. Fly from Purdue University Airport (LAF) to Lambert–St. Louis International Airport (STL)plane plane LAF - STL
    8h 20m
    $103–514

Indianapolis to East Saint Louis by bus and train (Greyhound)

Calendar21Weekly Services
Duration4h 11mAverage Duration
Ticket$40Cheapest Price
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Questions & Answers

Map of how to get from Indianapolis to East Saint Louis.ExpandLaunch map view
  • Distance: 245.1 mi
  • Duration: 4h 11m

What companies run services between Indianapolis, IN, USA and East Saint Louis, IL, USA?

Greyhound USA operates a bus from Indianapolis Union Station to St Louis Bus Station 3 times a day. Tickets cost $35–70 and the journey takes 3h 55m. Alternatively, you can take a train from Indianapolis to 5TH & MISSOURI station via Chicago Union Station, St. Louis, and CIVIC CENTER station in around 11h 2m.

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