There are 5 ways to get from Indianapolis to Florence Station by plane, bus (Flixbus, Greyhound), train (Amtrak), car, train, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly
best- Fly from Indianapolis (IND) to Florence Regional Airport (FLO)plane IND - FLO
6h 5m$87–444Bus
- Take the bus from Indianapolis to Atlanta Bus Stationbus FlixBus 2512
- Take the bus from Atlanta Bus Station to Florence Bus Stationbus Greyhound US0641S / ...
18h 49m$135–233Train (Amtrak)
- Take the train from Indianapolis to Alexandriatrain Cardinal
- Take the train from Alexandria to Florence Stationtrain Palmetto / ...
26h 41m$347–737Drive 661.1 mi
- Drive from Indianapolis to Florence Stationcar 661.1 mi
12h 16m$121–175Train, bus
- Take the train from Indianapolis to Ashland Amtrak Stationtrain
- Take the bus from Ashland to Statesvillebus
- Take the bus from Statesville to Charlotte Bus Stationbus
- Take the bus from Charlotte Bus Station to Camdenbus
- Take the bus from Camden to Florence Bus Stationbus
20h 39m$136–319
Indianapolis to Florence Station by train (Amtrak)
Questions & Answers
The cheapest way to get from Indianapolis to Florence Station is to drive which costs $120 - $180 and takes 12h 16m.
The fastest way to get from Indianapolis to Florence Station is to fly which takes 6h 5m and costs $85 - $450.
No, there is no direct bus from Indianapolis to Florence Station station. However, there are services departing from Indianapolis and arriving at Florence Bus Station via Atlanta Bus Station. The journey, including transfers, takes approximately 18h 49m.
No, there is no direct train from Indianapolis to Florence Station station. However, there are services departing from Indianapolis and arriving at Florence Station via Alexandria. The journey, including transfers, takes approximately 26h 41m.
The distance between Indianapolis and Florence Station is 547 miles. The road distance is 664.9 miles.
The best way to get from Indianapolis to Florence Station without a car is to bus which takes 18h 49m and costs $130 - $240.
It takes approximately 6h 5m to get from Indianapolis to Florence Station, including transfers.
Indianapolis to Florence Station bus services, operated by Flixbus USA, depart from Indianapolis station.
Indianapolis to Florence Station train services, operated by Amtrak, depart from Indianapolis station.
The best way to get from Indianapolis to Florence Station is to fly which takes 6h 5m and costs $85 - $450. Alternatively, you can bus, which costs $130 - $240 and takes 18h 49m, you could also train, which costs $340 - $750 and takes 26h 41m.
What companies run services between Indianapolis, IN, USA and Florence Station, SC, USA?
American Airlines flies from Indianapolis (IND) to Florence Regional Airport (FLO) 4 times a day. Alternatively, you can take a bus from Indianapolis to Florence Station via Atlanta Bus Station and Florence Bus Station in around 18h 49m.
- Website
- aa.com
Flights from Indianapolis to Florence Regional Airport via Charlotte
- Ave. Duration
- 6h 5m
- When
- Every day
- Estimated price
- $75–430
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Indianapolis to Alexandria
- Ave. Duration
- 18h 12m
- Frequency
- 3 times a week
- Estimated price
- $220–470
- Website
- Amtrak
Train from Alexandria to Florence Station
- Ave. Duration
- 7h 29m
- Frequency
- Twice daily
- Estimated price
- $120–270
- Website
- Amtrak
Train from Indianapolis to Ashland Amtrak Station
- Ave. Duration
- 6h 30m
- Frequency
- 3 times a week
- Estimated price
- $85–180
- Website
- Amtrak
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Indianapolis to Atlanta Bus Station
- Ave. Duration
- 11h 5m
- Frequency
- 3 times a day
- Estimated price
- $90–150
- Schedules at
- Flixbus USA
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Atlanta Bus Station to Florence Bus Station
- Ave. Duration
- 6h 20m
- Frequency
- 4 times a day
- Estimated price
- $45–85
- Website
- Greyhound
Bus from Charlotte Bus Station to Camden
- Ave. Duration
- 1h 35m
- Frequency
- Twice daily
- Estimated price
- $11–23
- Website
- Greyhound
Bus from Camden to Florence Bus Station
- Ave. Duration
- 1h
- Frequency
- 4 times a day
- Estimated price
- $7–14
- Website
- Greyhound
- Phone
- +1 888-378-3823
- [email protected]
- Website
- Barons Bus
Bus from Ashland to Statesville
- Ave. Duration
- 6h 20m
- Frequency
- Once daily
- Estimated price
- $28–70
- Website
- Barons Bus
Bus from Statesville to Charlotte Bus Station
- Ave. Duration
- 50 min
- Frequency
- Once daily
- Estimated price
- $4–35
- Website
- Barons Bus
Want to know more about travelling around United States
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More Questions & Answers
Indianapolis to Florence Station bus services, operated by Flixbus USA, arrive at Atlanta Bus Station.
Indianapolis to Florence Station train services, operated by Amtrak, arrive at Alexandria station.
Yes, the driving distance between Indianapolis to Florence Station is 665 miles. It takes approximately 12h 16m to drive from Indianapolis to Florence Station.
Book your Indianapolis to Florence Station train tickets online with Omio.
There are 47+ hotels available in Florence Station.










