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How to get fromIndianapolis to Florida Keysby plane, bus (Greyhound, Flixbus), car, shuttle, bus, or bus (Flixbus, Greyhound)

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There are 7 ways to get from Indianapolis to Florida Keys by plane, bus (Greyhound, Flixbus), car, shuttle, bus, or bus (Flixbus, Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Indianapolis to Key West International Airport

    best
    1. Fly from Indianapolis (IND) to Key West International Airport (EYW)plane plane IND - EYW
    7h 12m
    $169–556

  2. Bus

    1. Take the bus from Indianapolis Union Station to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta Bus Station to Miami Airport Stationbus bus
    3. Take the bus from Miami Airport Station to Big Pine Keybus bus
    32h 5m
    $230–371

  3. Drive  1,270.7 mi

    1. Drive from Indianapolis to Florida Keyscar car 1,270.7 mi
    23h 36m
    $232–335

  4. Fly Indianapolis to Miami International Airport, shuttle

    1. Fly from Indianapolis (IND) to Miami International Airport (MIA)plane plane IND - MIA
    2. Take a shuttle bus from Miami, FL - International Airport to Big Pine Key, FLshuttle bus
    10h 1m
    $254–736

  5. Fly Indianapolis to Fort Lauderdale–Hollywood International Airport, shuttle

    1. Fly from Indianapolis (IND) to Fort Lauderdale–Hollywood International Airport (FLL)plane plane IND - FLL
    2. Take a shuttle bus from Fort Lauderdale, FL - International Airport to Big Pine Key, FLshuttle bus
    10h 20m
    $674–1,406

  6. Bus to Covington, fly to Key West International Airport

    1. Take the bus from Indianapolis to Cincinnatibus bus
    2. Fly from Covington (CVG) to Key West International Airport (EYW)plane plane CVG - EYW
    9h 43m
    $217–725

  7. Bus #2

    1. Take the bus from Indianapolis to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta Bus Station to Miami Airport Stationbus bus
    3. Take the bus from Miami Airport Station to Big Pine Keybus bus
    32h 5m
    $224–361

Indianapolis to Florida Keys by bus and foot

Calendar14Weekly Services
Duration32h 5mAverage Duration
Ticket$230Cheapest Price
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Comparing Your Travel Options

Map of how to get from Indianapolis to Florida Keys.ExpandLaunch map view
  • Distance: 1,117.3 mi
  • Duration: 7h 12m

What companies run services between Indianapolis, IN, USA and Florida Keys, FL, USA?

Allegiant Air, Delta, and American Airlines fly from Indianapolis (IND) to Key West International Airport (EYW) every 4 hours. Alternatively, you can take a bus from Indianapolis Union Station to Florida Keys via Atlanta Bus Station, Miami Airport Station, Big Pine Key, Big Pine Key - CVS / MM30, and Sugarloaf Key - Lower - Sugarloaf Lodge in around 32h 5m.

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