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How to get fromIndianapolis to Great Smoky Mountainsby plane, car, train, or bus

Find Transport to Great Smoky Mountains

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There are 8 ways to get from Indianapolis to Great Smoky Mountains by plane, car, train, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Mcghee Tyson Airport, drive

    best
    1. Fly from Indianapolis (IND) to Mcghee Tyson Airport (TYS)plane plane IND - TYS
    2. Drive from Mcghee Tyson Airport (TYS) to Great Smoky Mountainscar car
    6h 47m
    $132–768

  2. Drive 403.2 mi

    cheapest
    1. Drive from Indianapolis to Great Smoky Mountainscar car 403.2 mi
    7h 47m
    $74–107

  3. Train, bus, drive via Ironville

    1. Take the train from Indianapolis to Ashland Amtrak Stationtrain train
    2. Take the bus from Ashland Bus Station to Winston Salem(Trans Center)bus bus
    3. Take the bus from Winston Salem(Trans Center) to Asheville, NCbus bus
    4. Drive from Asheville, NC to Great Smoky Mountainscar car
    20h 8m
    $165–327

  4. Train, bus, drive

    1. Take the train from Indianapolis to Charlottesvilletrain train
    2. Take the train from Charlottesville to Greensborotrain train
    3. Take the bus from Greensboro Bus Stop to Asheville, NCbus bus
    4. Drive from Asheville, NC to Great Smoky Mountainscar car
    26h 11m
    $287–587

  5. Fly to Asheville Regional Airport, drive

    1. Fly from Indianapolis (IND) to Asheville Regional Airport (AVL)plane plane IND - AVL
    2. Drive from Asheville-Airport-AVL to Great Smoky Mountainscar car
    7h 29m
    $91–454

  6. Fly to Hartsfield-Jackson Atlanta International Airport, drive

    1. Fly from Indianapolis (IND) to Hartsfield-Jackson Atlanta International Airport (ATL)plane plane IND - ATL
    2. Drive from Atlanta-Airport-ATL to Great Smoky Mountainscar car
    7h 25m
    $167–1,057

  7. Fly to Nashville, drive

    1. Fly from Indianapolis (IND) to Nashville (BNA)plane plane IND - BNA
    2. Drive from Nashville-Airport-BNA to Great Smoky Mountainscar car
    7h 34m
    $352–1,167

  8. Bus, drive (Greyhound)

    1. Take the bus from Indianapolis Union Station to Columbusbus bus
    2. Take the bus from Columbus to Winston Salem(Trans Center)bus bus
    3. Take the bus from Winston Salem(Trans Center) to Asheville, NCbus bus
    4. Drive from Asheville, NC to Great Smoky Mountainscar car
    20h 33m
    $121–237

Indianapolis (IND) to Mcghee Tyson Airport (TYS) flights

Calendar144Weekly Planes
Duration4h 43mAverage Duration
Ticket$120Cheapest Price
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Questions & Answers

Map of how to get from Indianapolis to Great Smoky Mountains.ExpandLaunch map view
  • Distance: 372.9 mi
  • Duration: 6h 47m

What companies run services between Indianapolis, IN, USA and Great Smoky Mountains, TN, USA?

There is no direct connection from Indianapolis to Great Smoky Mountains. However, you can take the line 8 bus to Indianapolis Airport, walk to Indianapolis (IND) airport, fly to Mcghee Tyson Airport (TYS), then drive to Great Smoky Mountains. Alternatively, you can take a train from Indianapolis to Great Smoky Mountains via Ashland Amtrak Station, Ashland Bus Station, Winston Salem(Trans Center), and Asheville, NC in around 20h 8m.

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