There are 6 ways to get from Indianapolis to Isle of Palms by plane, bus (Flixbus, Greyhound), train (Amtrak), car, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Indianapolis
best- Fly from Indianapolis (IND) to Charleston International Airport (CHS)plane IND - CHS
5h 52m$177–582Drive 700.9 mi
cheapest- Drive from Indianapolis to Isle of Palmscar 700.9 mi
12h 56m$128–185Bus
- Take the bus from Indianapolis to Atlanta Bus Stationbus FlixBus 2512
- Take the bus from Atlanta Bus Station to Charleston Bus Stationbus Greyhound US0641S
23h 49m$213–358Train (Amtrak)
- Take the train from Indianapolis to Alexandriatrain Cardinal
- Take the train from Alexandria to Charleston Amtrak Stationtrain Silver Meteor / ...
28h 39m$433–871Bus to Covington, fly
- Take the bus from Indianapolis to Cincinnatibus
- Fly from Covington (CVG) to Charleston International Airport (CHS)plane CVG - CHS
6h 25m$189–1,143Bus, drive
- Take the bus from Indianapolis Union Station to Atlanta Bus Stationbus
- Take the bus from Atlanta Bus Station to Myrtle Beach Bus Stationbus
- Drive from Myrtle Beach Bus Station to S. Pinckney St / Society Rdcar
- Take the bus from S. Pinckney St / Society Rd to Stuart Engals Blvd / Wando Crossing Centerbus
25h 4m$168–308
Indianapolis (IND) to Charleston International Airport (CHS) flights
Questions & Answers
The cheapest way to get from Indianapolis to Isle of Palms is to drive which costs $120 - $190 and takes 12h 56m.
The fastest way to get from Indianapolis to Isle of Palms is to fly which takes 5h 52m and costs $170 - $600.
No, there is no direct bus from Indianapolis to Isle of Palms station. However, there are services departing from Indianapolis and arriving at Charleston Bus Station via Atlanta Bus Station. The journey, including transfers, takes approximately 23h 49m.
No, there is no direct train from Indianapolis to Isle of Palms station. However, there are services departing from Indianapolis and arriving at Charleston Amtrak Station via Alexandria. The journey, including transfers, takes approximately 28h 39m.
The distance between Indianapolis and Isle of Palms is 627 miles. The road distance is 705 miles.
The best way to get from Indianapolis to Isle of Palms without a car is to bus which takes 23h 49m and costs $210 - $360.
It takes approximately 5h 52m to get from Indianapolis to Isle of Palms, including transfers.
Indianapolis to Isle of Palms bus services, operated by Flixbus USA, depart from Indianapolis station.
Indianapolis to Isle of Palms train services, operated by Amtrak, depart from Indianapolis station.
The best way to get from Indianapolis to Isle of Palms is to fly which takes 5h 52m and costs $170 - $600. Alternatively, you can bus, which costs $210 - $360 and takes 23h 49m, you could also train, which costs $430 - $900 and takes 28h 39m.
What companies run services between Indianapolis, IN, USA and Isle of Palms, SC, USA?
American Airlines, Delta, and two other airlines fly from Indianapolis (IND) to Charleston International Airport (CHS) hourly. Alternatively, you can take a bus from Indianapolis to Isle of Palms via Atlanta Bus Station and Charleston Bus Station in around 23h 49m.
- Website
- delta.com
Flights from Indianapolis to Charleston International Airport via Atlanta
- Ave. Duration
- 4h 12m
- When
- Every day
- Estimated price
- $95–500
Flights from Indianapolis to Charleston International Airport via Detroit
- Ave. Duration
- 5h 28m
- When
- Every day
- Estimated price
- $110–550
Flights from Covington to Charleston International Airport via Atlanta
- Ave. Duration
- 3h 58m
- When
- Every day
- Estimated price
- $100–550
- Website
- southwest.com
Flights from Indianapolis to Charleston International Airport via Chicago Midway
- Ave. Duration
- 4h 25m
- When
- Saturday, Sunday, Monday, Thursday, and Friday
- Estimated price
- $110–550
Flights from Indianapolis to Charleston International Airport via Nashville
- Ave. Duration
- 5h 10m
- When
- Monday, Thursday, Friday, and Saturday
- Estimated price
- $95–500
Flights from Indianapolis to Charleston International Airport via Baltimore
- Ave. Duration
- 5h 32m
- When
- Every day
- Estimated price
- $120–600
Flights from Covington to Charleston International Airport via Nashville
- Ave. Duration
- 3h 40m
- When
- Sunday
- Estimated price
- $100–550
- Website
- aa.com
Flights from Indianapolis to Charleston International Airport via Charlotte
- Ave. Duration
- 4h 35m
- When
- Every day
- Estimated price
- $85–470
Flights from Covington to Charleston International Airport via Charlotte
- Ave. Duration
- 3h 41m
- When
- Every day
- Estimated price
- $85–490
- Website
- united.com
Flights from Indianapolis to Charleston International Airport via Washington Dulles
- Ave. Duration
- 4h 35m
- When
- Every day
- Estimated price
- $110–550
- Website
- flybreeze.com
Flights from Covington to Charleston International Airport
- Ave. Duration
- 1h 39m
- When
- Tuesday, Thursday, and Sunday
- Estimated price
- $80–800
- Website
- allegiantair.com
Flights from Covington to Charleston International Airport
- Ave. Duration
- 1h 37m
- When
- Thursday and Sunday
- Estimated price
- $85–490
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Indianapolis to Alexandria
- Ave. Duration
- 18h 12m
- Frequency
- 3 times a week
- Estimated price
- $220–470
- Website
- Amtrak
Train from Alexandria to Charleston Amtrak Station
- Ave. Duration
- 9h 3m
- Frequency
- Twice daily
- Estimated price
- $150–330
- Website
- Amtrak
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Indianapolis to Atlanta Bus Station
- Ave. Duration
- 11h 5m
- Frequency
- 3 times a day
- Estimated price
- $85–150
- Schedules at
- Flixbus USA
Bus from Indianapolis to Cincinnati
- Ave. Duration
- 2h
- Frequency
- 3 times a day
- Estimated price
- $17–29
- Schedules at
- Flixbus USA
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Atlanta Bus Station to Charleston Bus Station
- Ave. Duration
- 11h 20m
- Frequency
- Twice daily
- Estimated price
- $65–140
- Website
- Greyhound
Bus from Indianapolis Union Station to Atlanta Bus Station
- Ave. Duration
- 11h 25m
- Frequency
- Every 4 hours
- Estimated price
- $80–160
- Website
- Greyhound
Bus from Atlanta Bus Station to Myrtle Beach Bus Station
- Ave. Duration
- 8h 40m
- Frequency
- Twice daily
- Estimated price
- $55–110
- Website
- Greyhound
- Website
- ridetricountylink.com
Bus from S. Pinckney St / Society Rd to Stuart Engals Blvd / Wando Crossing Center
- Ave. Duration
- 1h 30m
- Frequency
- Once daily
- Estimated price
- $1–3
- Schedules at
- ridetricountylink.com
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More Questions & Answers
Indianapolis to Isle of Palms bus services, operated by Flixbus USA, arrive at Atlanta Bus Station.
Indianapolis to Isle of Palms train services, operated by Amtrak, arrive at Alexandria station.
Yes, the driving distance between Indianapolis to Isle of Palms is 705 miles. It takes approximately 12h 56m to drive from Indianapolis to Isle of Palms.
There are 1241+ hotels available in Isle of Palms.






