Rome2Rio

How to get fromIndianapolis to Jacksonby bus (Greyhound), car, plane, bus, train, or taxi

Find Transport to Jackson

See all options

There are 7 ways to get from Indianapolis to Jackson by bus (Greyhound), car, plane, bus, train, or taxi

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus (Greyhound)

    best
    1. Take the bus from Indianapolis Union Station to St Louis Bus Stationbus bus Greyhound US0421
    2. Take the bus from St Louis Bus Station to Cape Girardeaubus bus Greyhound US1173
    7h 13m
    $75–131

  2. Drive 314.2 mi

    cheapest
    1. Drive from Indianapolis to Jacksoncar car 314.2 mi
    5h 26m
    $58–83

  3. Fly Indianapolis to Williamson County Regional Airport, drive

    1. Fly from Indianapolis (IND) to Williamson County Regional Airport (MWA)plane plane IND - MWA
    2. Drive from Williamson County Regional Airport (MWA) to Jacksoncar car
    7h 9m
    $84–430

  4. Bus, train, taxi

    1. Take the bus from Indianapolis Union Station to Champaign Intermodal Trans Ctrbus bus
    2. Take the train from Champaign-Urbana to Carbondaletrain train
    3. Take the taxi from Carbondale to Jacksontaxi taxi
    7h 14m
    $193–304

  5. Fly Indianapolis to Barkley Regional Airport, drive

    1. Fly from Indianapolis (IND) to Barkley Regional Airport (PAH)plane plane IND - PAH
    2. Drive from Barkley Regional Airport (PAH) to Jacksoncar car
    9h 40m
    $90–451

  6. Train to Chicago O'Hare International Airport, fly to Cape Girardeau Municipal Airport

    1. Take the train from Indianapolis to Chicago Union Stationtrain train
    2. Fly from Chicago O'Hare International Airport (ORD) to Cape Girardeau Municipal Airport (CGI)plane plane ORD - CGI
    9h 2m
    $195–399

  7. Fly Indianapolis to Cape Girardeau Municipal Airport

    1. Fly from Indianapolis (IND) to Cape Girardeau Municipal Airport (CGI)plane plane IND - CGI
    7h 59m
    $177–697

Indianapolis (IND) to Williamson County Regional Airport (MWA) flights

Calendar25Weekly Planes
Duration5h 6mAverage Duration
Ticket$72Cheapest Price
See schedules

Questions & Answers

Map of how to get from Indianapolis to Jackson.ExpandLaunch map view
  • Distance: 364.2 mi
  • Duration: 7h 13m

What companies run services between Indianapolis, IN, USA and Jackson, MO, USA?

You can take a bus from Indianapolis Union Station to Jackson via St Louis Bus Station and Cape Girardeau in around 7h 13m. Alternatively, United Airlines, Corporate Flight Management Inc, and two other airlines fly from Indianapolis (IND) to Cape Girardeau Municipal Airport (CGI) twice daily.

Airlines
Train operators
Bus operators
Other operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers