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How to get fromIndianapolis to Jefferson Cityby bus, train, train (Amtrak), car, plane, bus (Greyhound), or shuttle

Find Transport to Jefferson City

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There are 8 ways to get from Indianapolis to Jefferson City by bus, train, train (Amtrak), car, plane, bus (Greyhound), or shuttle

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus, train

    best
    1. Take the bus from Indianapolis Union Station to St Louis Bus Stationbus bus Greyhound US0421
    2. Take the train from St. Louis to Jefferson City Stationtrain train Missouri River Runner / ...
    7h 20m
    $108–173

  2. Drive  363.4 mi

    cheapest
    1. Drive from Indianapolis to Jefferson Citycar car 363.4 mi
    6h 16m
    $67–96

  3. Train (Amtrak)

    1. Take the train from Indianapolis to Chicago Union Stationtrain train Cardinal
    2. Take the train from Chicago Union Station to Jefferson City Stationtrain train Lincoln Service Missouri River Runner
    13h 46m
    $328–516

  4. Fly Indianapolis to Columbia Regional Airport

    1. Fly from Indianapolis (IND) to Columbia Regional Airport (COU)plane plane IND - COU
    6h 12m
    $162–552

  5. Bus (Greyhound)

    1. Take the bus from Indianapolis Union Station to St Louis Bus Stationbus bus Greyhound US0421
    2. Take the bus from St Louis Bus Station to Jefferson Citybus bus Greyhound US0175s
    9h 3m
    $81–119

  6. Train to Purdue University Airport, fly to Columbia Regional Airport

    1. Take the train from Indianapolis to Lafayette Amtrak Stationtrain train
    2. Fly from Purdue University Airport (LAF) to Columbia Regional Airport (COU)plane plane LAF - COU
    9h 43m
    $188–525

  7. Fly Indianapolis to Lambert–St. Louis International Airport, shuttle

    1. Fly from Indianapolis (IND) to Lambert–St. Louis International Airport (STL)plane plane IND - STL
    2. Take a shuttle bus from St Louis International Airport to Jefferson City, Missourishuttle bus
    8h 1m
    $997–1,052

  8. Bus, train to Chicago O'Hare International Airport, fly to Columbia Regional Airport

    1. Take the bus from Indianapolis to Gary Bus Stationbus bus
    2. Take the train from Gary to Van Buren St.train train
    3. Fly from Chicago O'Hare International Airport (ORD) to Columbia Regional Airport (COU)plane plane ORD - COU
    7h 53m
    $164–431

Indianapolis to Jefferson City by bus and train

Calendar14Weekly Services
Duration7h 20mAverage Duration
Ticket$108Cheapest Price
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Comparing Your Travel Options

Map of how to get from Indianapolis to Jefferson City.ExpandLaunch map view
  • Distance: 363.6 mi
  • Duration: 7h 20m

What companies run services between Indianapolis, IN, USA and Jefferson City, MO, USA?

You can take a train from Indianapolis to Jefferson City Station via Chicago Union Station in around 13h 46m. Alternatively, United Airlines, American Airlines, and Allegiant Air fly from Indianapolis (IND) to Columbia Regional Airport (COU) every 3 hours.

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