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How to get fromIndianapolis to La Crosse Amtrak Stationby bus, train, bus (Flixbus, Greyhound), car, plane, or train (Amtrak)

Find Transport to La Crosse Amtrak Station

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There are 6 ways to get from Indianapolis to La Crosse Amtrak Station by bus, train, bus (Flixbus, Greyhound), car, plane, or train (Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus, train

    best
    1. Take the bus from Indianapolis Union Station to Chicago Union Stationbus bus
    2. Take the train from Chicago Union Station to La Crosse Amtrak Stationtrain train Empire Builder / ...
    9h 39m
    $113–242

  2. Fly from Indianapolis

    cheapest
    1. Fly from Indianapolis (IND) to La Crosse (LSE)plane plane IND - LSE
    5h 52m
    $75–408

  3. Bus

    1. Take the bus from Indianapolis to Chicago Bus Stationbus bus
    2. Take the bus from Chicago Bus Station to Milwaukee Intermodal Stationbus bus
    3. Take the bus from Milwaukee to La Crossebus bus
    11h 4m
    $97–154

  4. Drive 459.6 mi

    1. Drive from Indianapolis to La Crosse Amtrak Stationcar car 459.6 mi
    7h 46m
    $84–122

  5. Train (Amtrak)

    1. Take the train from Indianapolis to Chicago Union Stationtrain train Cardinal
    2. Take the train from Chicago Union Station to La Crosse Amtrak Stationtrain train Empire Builder / ...
    10h 59m
    $145–317

  6. Train to Purdue University Airport, fly

    1. Take the train from Indianapolis to Lafayette Amtrak Stationtrain train
    2. Fly from Purdue University Airport (LAF) to La Crosse (LSE)plane plane LAF - LSE
    7h 48m
    $87–386

Indianapolis to La Crosse Amtrak Station by bus and train

Calendar21Weekly Services
Duration9h 39mAverage Duration
Ticket$113Cheapest Price
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Questions & Answers

Map of how to get from Indianapolis to La Crosse Amtrak Station.ExpandLaunch map view
  • Distance: 464.8 mi
  • Duration: 9h 39m

What companies run services between Indianapolis, IN, USA and La Crosse Amtrak Station, WI, USA?

You can take a bus from Indianapolis to La Crosse Amtrak Station via Chicago Bus Station, Milwaukee Intermodal Station, Milwaukee, and La Crosse in around 11h 4m. Alternatively, United Airlines and American Airlines fly from Indianapolis (IND) to La Crosse (LSE) every 4 hours.

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