There are 6 ways to get from Indianapolis to La Salle by bus (Greyhound), train (Amtrak), car, plane, train, taxi, or bus (Flixbus, Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus via Champaign (Greyhound)
best- Take the bus from Indianapolis Union Station to Champaign Intermodal Trans Ctrbus Greyhound US0157S
- Take the bus from Champaign Intermodal Trans Ctr to Oglesbybus Greyhound US0145S
5h 20m$55–95Drive 230.7 mi
cheapest- Drive from Indianapolis to La Sallecar 230.7 mi
3h 59m$43–61Train (Amtrak)
- Take the train from Indianapolis to Chicago Union Stationtrain Cardinal
- Take the train from Chicago Union Station to Mendota Stationtrain Southwest Chief / ...
7h 48m$130–241Fly to Chicago O'Hare International Airport, train, taxi
- Fly from Indianapolis (IND) to Chicago O'Hare International Airport (ORD)plane IND - ORD
- Take the train from Chicago Union Station to Mendota Stationtrain
- Take the taxi from Mendota Station to La Salletaxi
6h 52m$494–1,222Bus
- Take the bus from Indianapolis to Chicago Bus Stationbus FlixBus 2511 / ...
- Take the bus from Chicago Bus Station to Oglesbybus Greyhound US0145S
8h 25m$72–116Fly to Chicago Midway International Airport, train, taxi
- Fly from Indianapolis (IND) to Chicago Midway International Airport (MDW)plane IND - MDW
- Take the train from Chicago Union Station to Mendota Stationtrain
- Take the taxi from Mendota Station to La Salletaxi
6h 34m$122–455
Indianapolis (IND) to Chicago O'Hare International Airport (ORD) flights
Questions & Answers
The cheapest way to get from Indianapolis to La Salle is to drive which costs $40 - $65 and takes 3h 59m.
The fastest way to get from Indianapolis to La Salle is to drive which takes 3h 59m and costs $40 - $65.
No, there is no direct bus from Indianapolis station to La Salle. However, there are services departing from Indianapolis Union Station and arriving at Oglesby via Champaign Intermodal Trans Ctr. The journey, including transfers, takes approximately 5h 20m.
No, there is no direct train from Indianapolis to La Salle station. However, there are services departing from Indianapolis and arriving at Mendota Station via Chicago Union Station. The journey, including transfers, takes approximately 7h 48m.
The distance between Indianapolis and La Salle is 234 miles. The road distance is 232 miles.
The best way to get from Indianapolis to La Salle without a car is to bus via Champaign which takes 5h 20m and costs $55 - $95.
It takes approximately 5h 20m to get from Indianapolis to La Salle, including transfers.
Indianapolis to La Salle bus services, operated by Greyhound USA, depart from Indianapolis Union Station.
Indianapolis to La Salle train services, operated by Amtrak, depart from Indianapolis station.
The best way to get from Indianapolis to La Salle is to bus via Champaign which takes 5h 20m and costs $55 - $95. Alternatively, you can train, which costs $130 - $250 and takes 7h 48m.
What companies run services between Indianapolis, IN, USA and La Salle, IL, USA?
You can take a bus from Indianapolis Union Station to La Salle via Champaign Intermodal Trans Ctr and Oglesby in around 5h 20m. Alternatively, you can take a train from Indianapolis to La Salle via Chicago Union Station and Mendota Station in around 7h 48m.
- Website
- united.com
Flights from Indianapolis to Chicago O'Hare International Airport
- Ave. Duration
- 1h 22m
- When
- Every day
- Estimated price
- $35–280
- Website
- aa.com
Flights from Indianapolis to Chicago O'Hare International Airport
- Ave. Duration
- 1h 28m
- When
- Every day
- Estimated price
- $35–280
- Website
- southwest.com
Flights from Indianapolis to Chicago Midway International Airport
- Ave. Duration
- 1h 2m
- When
- Every day
- Estimated price
- $45–330
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Indianapolis to Chicago Union Station
- Ave. Duration
- 5h
- Frequency
- 3 times a week
- Estimated price
- $60–130
- Website
- Amtrak
Train from Chicago Union Station to Mendota Station
- Ave. Duration
- 1h 23m
- Frequency
- 3 times a day
- Estimated price
- $25–55
- Website
- Amtrak
Train from Chicago Union Station to Mendota Station
- Ave. Duration
- 1h 23m
- Frequency
- 3 times a day
- Estimated price
- $25–55
- Website
- Amtrak
Train from Chicago Union Station to Mendota Station
- Ave. Duration
- 1h 23m
- Frequency
- 3 times a day
- Estimated price
- $25–55
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Indianapolis Union Station to Champaign Intermodal Trans Ctr
- Ave. Duration
- 2h 5m
- Frequency
- Once daily
- Estimated price
- $17–35
- Website
- Greyhound
Bus from Champaign Intermodal Trans Ctr to Oglesby
- Ave. Duration
- 2h 10m
- Frequency
- Once daily
- Estimated price
- $16–35
- Website
- Greyhound
Bus from Chicago Bus Station to Oglesby
- Ave. Duration
- 3h 40m
- Frequency
- Once daily
- Estimated price
- $23–45
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Indianapolis to Chicago Bus Station
- Ave. Duration
- 3h 40m
- Frequency
- Every 4 hours
- Estimated price
- $27–45
- Schedules at
- Flixbus USA
- Ave. Duration
- 25 min
- Estimated price
- $45–60
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide
Why you should take the train in the US
Read the travel guide
More Questions & Answers
Indianapolis to La Salle bus services, operated by Greyhound USA, arrive at Champaign Intermodal Trans Ctr station.
La Salle is 1h behind Indianapolis. It is currently 3:27 AM in Indianapolis and 2:27 AM in La Salle.
Indianapolis to La Salle train services, operated by Amtrak, arrive at Chicago Union Station.
Yes, the driving distance between Indianapolis to La Salle is 232 miles. It takes approximately 3h 59m to drive from Indianapolis to La Salle.
Book your Indianapolis to La Salle bus tickets online with Omio.
There are 33+ hotels available in La Salle.






