There are 8 ways to get from Indianapolis to Lexington by plane, train, bus, train (Amtrak), car, or bus (Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Piedmont Triad International Airport
best- Fly from Indianapolis (IND) to Piedmont Triad International Airport (GSO)plane IND - GSO
8h 27m$143–729Bus
cheapest- Take the bus from Indianapolis Union Station to Columbusbus
- Take the bus from Columbus to Winston Salem(Trans Center)bus
- Take the bus from Winston Salem(Trans Center) to Lexington Davidson Co Trans Termbus
17h 5m$93–180Train, bus
- Take the train from Indianapolis to Ashland Amtrak Stationtrain
- Take the bus from Ashland Bus Station to Winston Salem(Trans Center)bus
- Take the bus from Winston Salem(Trans Center) to Lexington Davidson Co Trans Termbus
16h 40m$136–270Train (Amtrak)
- Take the train from Indianapolis to Charlottesvilletrain Cardinal
- Take the train from Charlottesville to High Pointtrain Crescent
21h 42m$250–533Drive 532.5 mi
- Drive from Indianapolis to Lexingtoncar 532.5 mi
9h 29m$98–141Fly to Charlotte Douglas International Airport, train
- Fly from Indianapolis (IND) to Charlotte Douglas International Airport (CLT)plane IND - CLT
- Take the train from Charlotte Amtrak Station to High Pointtrain
8h 18m$132–667Fly to Raleigh-Durham International Airport, train
- Fly from Indianapolis (IND) to Raleigh-Durham International Airport (RDU)plane IND - RDU
- Take the train from Durham Amtrak Station to High Pointtrain
8h 50m$117–552Fly to Concord, train, bus
- Fly from Indianapolis (IND) to Concord (USA)plane IND - USA
- Take the train from Kannapolis to High Pointtrain
- Take the bus from High Point Transportation Terminal to Lexington Davidson Co Trans Termbus
6h 46m$200–516
Indianapolis to Lexington by train and bus
Questions & Answers
The cheapest way to get from Indianapolis to Lexington is to bus which costs $90 - $180 and takes 17h 5m.
The fastest way to get from Indianapolis to Lexington is to fly and train and bus which takes 6h 46m and costs $200 - $550.
No, there is no direct bus from Indianapolis station to Lexington. However, there are services departing from Indianapolis Union Station and arriving at Lexington Davidson Co Trans Term via Columbus and Winston Salem(Trans Center). The journey, including transfers, takes approximately 17h 5m.
No, there is no direct train from Indianapolis to Lexington. However, there are services departing from Indianapolis and arriving at High Point via Charlottesville. The journey, including transfers, takes approximately 21h 42m.
The distance between Indianapolis and Lexington is 479 miles. The road distance is 535.6 miles.
The best way to get from Indianapolis to Lexington without a car is to train and bus which takes 16h 40m and costs $130 - $270.
It takes approximately 8h 27m to get from Indianapolis to Lexington, including transfers.
Indianapolis to Lexington bus services, operated by Greyhound USA, depart from Indianapolis Union Station.
Indianapolis to Lexington train services, operated by Amtrak, depart from Indianapolis station.
The best way to get from Indianapolis to Lexington is to fly which takes 8h 27m and costs $140 - $750. Alternatively, you can train, which costs $250 - $550 and takes 21h 42m, you could also bus, which costs $90 - $180 and takes 17h 5m.
What companies run services between Indianapolis, IN, USA and Lexington, NC, USA?
United Airlines, Delta, and American Airlines fly from Indianapolis (IND) to Piedmont Triad International Airport (GSO) hourly. Alternatively, you can take a train from Indianapolis to Lexington Davidson Co Trans Term via Charlottesville, High Point, and High Point Transportation Terminal in around 21h 42m.
- Website
- aa.com
Flights from Indianapolis to Piedmont Triad International Airport via Charlotte Douglas International Airport
- Ave. Duration
- 5h 11m
- When
- Every day
- Estimated price
- $120–700
Flights from Indianapolis to Piedmont Triad International Airport via Philadelphia
- Ave. Duration
- 5h 26m
- When
- Every day
- Estimated price
- $180–900
Flights from Indianapolis to Piedmont Triad International Airport via Reagan Washington
- Ave. Duration
- 5h 4m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $150–800
Flights from Indianapolis to Piedmont Triad International Airport via Chicago O'Hare
- Ave. Duration
- 5h 41m
- When
- Every day
- Estimated price
- $160–800
Flights from Indianapolis to Charlotte Douglas International Airport
- Ave. Duration
- 1h 44m
- When
- Every day
- Estimated price
- $100–600
Flights from Indianapolis to Raleigh-Durham International Airport via Charlotte Douglas International Airport
- Ave. Duration
- 3h 33m
- When
- Every day
- Estimated price
- $90–550
- Website
- delta.com
Flights from Indianapolis to Piedmont Triad International Airport via Atlanta
- Ave. Duration
- 4h 45m
- When
- Every day
- Estimated price
- $150–800
Flights from Indianapolis to Piedmont Triad International Airport via Detroit
- Ave. Duration
- 4h 17m
- When
- Every day
- Estimated price
- $150–800
Flights from Indianapolis to Charlotte Douglas International Airport via Atlanta
- Ave. Duration
- 4h
- When
- Every day
- Estimated price
- $130–700
Flights from Indianapolis to Charlotte Douglas International Airport via Detroit
- Ave. Duration
- 4h 20m
- When
- Every day
- Estimated price
- $140–750
Flights from Indianapolis to Raleigh-Durham International Airport
- Ave. Duration
- 1h 50m
- When
- Every day
- Estimated price
- $85–490
Flights from Indianapolis to Raleigh-Durham International Airport via Detroit
- Ave. Duration
- 4h 2m
- When
- Every day
- Estimated price
- $110–600
Flights from Indianapolis to Raleigh-Durham International Airport via Atlanta
- Ave. Duration
- 4h 5m
- When
- Sunday, Monday, Tuesday, Wednesday, Thursday, and Friday
- Estimated price
- $110–600
- Website
- southwest.com
Flights from Indianapolis to Charlotte Douglas International Airport via Nashville
- Ave. Duration
- 3h 51m
- When
- Every day
- Estimated price
- $120–700
Flights from Indianapolis to Charlotte Douglas International Airport via Chicago Midway
- Ave. Duration
- 4h 5m
- When
- Saturday, Tuesday, and Wednesday
- Estimated price
- $140–750
Flights from Indianapolis to Raleigh-Durham International Airport via Nashville
- Ave. Duration
- 3h 40m
- When
- Monday to Wednesday
- Estimated price
- $100–550
Flights from Indianapolis to Raleigh-Durham International Airport via Baltimore
- Ave. Duration
- 3h 48m
- When
- Saturday, Tuesday, and Wednesday
- Estimated price
- $110–600
Flights from Indianapolis to Raleigh-Durham International Airport via Chicago Midway
- Ave. Duration
- 3h 51m
- When
- Saturday, Sunday, Tuesday, and Wednesday
- Estimated price
- $110–600
- Website
- united.com
Flights from Indianapolis to Piedmont Triad International Airport via Washington Dulles
- Ave. Duration
- 4h 6m
- When
- Every day
- Estimated price
- $150–800
Flights from Indianapolis to Piedmont Triad International Airport via Chicago O'Hare
- Ave. Duration
- 4h 48m
- When
- Every day
- Estimated price
- $160–800
Flights from Indianapolis to Piedmont Triad International Airport via Newark
- Ave. Duration
- 4h 47m
- When
- Every day
- Estimated price
- $200–950
Flights from Indianapolis to Raleigh-Durham International Airport via Washington Dulles
- Ave. Duration
- 3h 57m
- When
- Every day
- Estimated price
- $100–550
- Website
- aveloair.com
Flights from Indianapolis to Concord
- Ave. Duration
- 1h 27m
- When
- Thursday and Sunday
- Estimated price
- $130–410
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Indianapolis to Ashland Amtrak Station
- Ave. Duration
- 6h 30m
- Frequency
- 3 times a week
- Estimated price
- $85–180
- Website
- Amtrak
Train from Indianapolis to Charlottesville
- Ave. Duration
- 15h 20m
- Frequency
- 3 times a week
- Estimated price
- $190–400
- Website
- Amtrak
Train from Charlottesville to High Point
- Ave. Duration
- 3h 57m
- Frequency
- Once daily
- Estimated price
- $55–130
- Website
- Amtrak
Train from Charlotte Amtrak Station to High Point
- Ave. Duration
- 1h 14m
- Frequency
- 5 times a day
- Estimated price
- $24–55
- Website
- Amtrak
Train from Durham Amtrak Station to High Point
- Ave. Duration
- 1h 19m
- Frequency
- 4 times a day
- Estimated price
- $22–50
- Website
- Amtrak
Train from Kannapolis to High Point
- Ave. Duration
- 49 min
- Frequency
- 3 times a day
- Estimated price
- $16–35
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Ashland Bus Station to Winston Salem(Trans Center)
- Ave. Duration
- 7h 5m
- Frequency
- Twice daily
- Estimated price
- $45–85
- Website
- Greyhound
Bus from Winston Salem(Trans Center) to Lexington Davidson Co Trans Term
- Ave. Duration
- 1h 5m
- Frequency
- Twice daily
- Estimated price
- $5–11
- Website
- Greyhound
Bus from High Point Transportation Terminal to Lexington Davidson Co Trans Term
- Ave. Duration
- 25 min
- Frequency
- Twice daily
- Estimated price
- $2–5
- Website
- Greyhound
Bus from Indianapolis Union Station to Columbus
- Ave. Duration
- 4h 40m
- Frequency
- Every 4 hours
- Estimated price
- $27–55
- Website
- Greyhound
Bus from Columbus to Winston Salem(Trans Center)
- Ave. Duration
- 9h 20m
- Frequency
- Twice daily
- Estimated price
- $60–120
- Website
- Greyhound
Bus from Winston Salem(Trans Center) to Lexington Davidson Co Trans Term
- Ave. Duration
- 1h 5m
- Frequency
- Twice daily
- Estimated price
- $5–11
- Website
- Greyhound
- Phone
- +1 704-348-1200
- [email protected]
- Website
- sunwaycharters.com
Bus from Winston Salem(Trans Center) to Lexington Davidson Co Trans Term
- Ave. Duration
- 28 min
- Frequency
- Once daily
- Estimated price
- $5–8
- Schedules at
- sunwaycharters.com
- Passenger
- $5–8
Bus from High Point Transportation Terminal to Lexington Davidson Co Trans Term
- Ave. Duration
- 25 min
- Frequency
- Once daily
- Estimated price
- $2–4
- Schedules at
- sunwaycharters.com
- Passenger
- $2–4
Bus from Winston Salem(Trans Center) to Lexington Davidson Co Trans Term
- Ave. Duration
- 28 min
- Frequency
- Once daily
- Estimated price
- $5–8
- Schedules at
- sunwaycharters.com
- Passenger
- $5–8
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More Questions & Answers
Indianapolis to Lexington bus services, operated by Greyhound USA, arrive at Columbus station.
Indianapolis to Lexington train services, operated by Amtrak, arrive at Charlottesville station.
Yes, the driving distance between Indianapolis to Lexington is 536 miles. It takes approximately 9h 29m to drive from Indianapolis to Lexington.
Book your Indianapolis to Lexington bus tickets online with Omio and FlixBus.
There are 41+ hotels available in Lexington.





