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How to get fromIndianapolis to Missouriby bus (Greyhound), bus, train, car, train (Amtrak), or plane

Find Transport to Missouri

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There are 9 ways to get from Indianapolis to Missouri by bus (Greyhound), bus, train, car, train (Amtrak), or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus (Greyhound)

    best
    1. Take the bus from Indianapolis Union Station to St Louis Bus Stationbus bus Greyhound US0421
    2. Take the bus from St Louis Bus Station to Kansas City Bus Stationbus bus Greyhound US0180s / ...
    8h 55m
    $73–124

  2. Bus, train via Galesburg

    1. Take the bus from Indianapolis Union Station to Galesburgbus bus Greyhound US0157S
    2. Take the train from Galesburg Amtrak Station to Kansas Citytrain train Southwest Chief
    10h 46m
    $105–223

  3. Bus, train

    1. Take the bus from Indianapolis Union Station to Bloomington-Normalbus bus Greyhound US0157S
    2. Take the train from Bloomington-Normal to Kansas Citytrain train Lincoln Service Missouri River Runner
    13h 14m
    $127–302

  4. Drive  481.9 mi

    1. Drive from Indianapolis to Kansas Citycar car 481.9 mi
    8h 4m
    $88–127

  5. Train

    1. Take the train from Indianapolis to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Napervilletrain train
    3. Take the train from Naperville Amtrak Station to Kansas Citytrain train
    14h 26m
    $153–360

  6. Fly to Lambert–St. Louis International Airport

    1. Fly from Indianapolis (IND) to Lambert–St. Louis International Airport (STL)plane plane IND - STL
    5h 54m
    $865–905

  7. Fly to Kansas City

    1. Fly from Indianapolis (IND) to Kansas City (MCI)plane plane IND - MCI
    4h 56m
    $602–1,002

  8. Fly to Columbia Regional Airport

    1. Fly from Indianapolis (IND) to Columbia Regional Airport (COU)plane plane IND - COU
    5h 54m
    $122–507

  9. Fly to Springfield-Branson National Airport

    1. Fly from Indianapolis (IND) to Springfield-Branson National Airport (SGF)plane plane IND - SGF
    6h 35m
    $98–492

Indianapolis to Missouri by bus (Greyhound)

Calendar21Weekly Buses
Duration8h 55mAverage Duration
Ticket$73Cheapest Price
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Comparing Your Travel Options

Map of how to get from Indianapolis to Missouri.ExpandLaunch map view
  • Distance: 489.3 mi
  • Duration: 8h 55m

What companies run services between Indianapolis, IN, USA and Missouri, USA?

You can take a bus from Indianapolis Union Station to Kansas City Bus Station via St Louis Bus Station in around 8h 55m. Alternatively, you can take a train from Indianapolis to Metro Center via Chicago Union Station, Naperville Amtrak Station, Kansas City, and Union Station in around 14h 26m.

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