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How to get fromIndianapolis to Myrtle Beachby plane, bus (Flixbus, Greyhound), train, bus, car, or bus (Greyhound)

Find Transport to Myrtle Beach

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There are 6 ways to get from Indianapolis to Myrtle Beach by plane, bus (Flixbus, Greyhound), train, bus, car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Indianapolis

    best
    1. Fly from Indianapolis (IND) to Myrtle Beach (MYR)plane plane IND - MYR
    5h 33m
    $83–436

  2. Bus via Atlanta

    1. Take the bus from Indianapolis to Atlanta Bus Stationbus bus FlixBus 2512
    2. Take the bus from Atlanta Bus Station to Myrtle Beach Bus Stationbus bus Greyhound US0641S
    21h 5m
    $155–232

  3. Train, bus

    1. Take the train from Indianapolis to Alexandriatrain train
    2. Take the train from Alexandria to Fayetteville Amtrak Stationtrain train
    3. Take the bus from Fayetteville Bus Station to Myrtle Beach Bus Stationbus bus
    29h 4m
    $588–915

  4. Drive  719.3 mi

    1. Drive from Indianapolis to Myrtle Beachcar car 719.3 mi
    13h 26m
    $132–190

  5. Bus to Covington, fly

    1. Take the bus from Indianapolis to Cincinnatibus bus
    2. Fly from Covington (CVG) to Myrtle Beach (MYR)plane plane CVG - MYR
    5h 59m
    $121–595

  6. Bus

    1. Take the bus from Indianapolis to Cincinnatibus bus
    2. Take the bus from Cincinnati to Columbusbus bus
    3. Take the bus from Columbus to Charlottebus bus
    4. Take the bus from Charlotte Bus Station to Camdenbus bus
    5. Take the bus from Camden to Myrtle Beach Bus Stationbus bus
    23h 45m
    $103–250

Indianapolis to Myrtle Beach by bus

Calendar7Weekly Buses
Duration21h 5mAverage Duration
Ticket$155Cheapest Price
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Comparing Your Travel Options

Map of how to get from Indianapolis to Myrtle Beach.ExpandLaunch map view
  • Distance: 601.8 mi
  • Duration: 5h 33m

What companies run services between Indianapolis, IN, USA and Myrtle Beach, SC, USA?

American Airlines, Delta, and Southwest Airlines fly from Indianapolis (IND) to Myrtle Beach (MYR) every 3 hours. Alternatively, you can take a bus from Indianapolis to Myrtle Beach Bus Station via Atlanta Bus Station in around 21h 5m.

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Need to know: Greyhound

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