There are 6 ways to get from Indianapolis to Orangeburg by plane, taxi, train, bus, car, bus (Flixbus, Greyhound), or bus (Greyhound, Flixbus)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Columbia, taxi
best- Fly from Indianapolis (IND) to Columbia (CAE)plane IND - CAE
- Take the taxi from Columbia-Airport-CAE to Orangeburgtaxi
5h 51m$197–582Fly to Augusta Regional Airport At Bush Field, drive
cheapest- Fly from Indianapolis (IND) to Augusta Regional Airport At Bush Field (AGS)plane IND - AGS
- Drive from Augusta Regional Airport At Bush Field (AGS) to Orangeburgcar
7h 4m$91–473Train, bus
- Take the train from Indianapolis to Ashland Amtrak Stationtrain
- Take the bus from Ashland to Charlotte Bus Stationbus
- Take the bus from Charlotte Bus Station to Orangeburgbus
19h 48m$154–296Drive 621.3 mi
- Drive from Indianapolis to Orangeburgcar 621.3 mi
11h 35m$114–164Bus via Atlanta
- Take the bus from Indianapolis to Atlanta Bus Stationbus
- Take the bus from Atlanta Bus Station to Camdenbus
- Take the bus from Camden to Orangeburgbus
20h 28m$142–225Bus
- Take the bus from Indianapolis Union Station to Wilson & Ferrell Shell Station - Columbusbus
- Take the bus from Columbus to Charlottebus
- Take the bus from Charlotte Bus Station to Orangeburgbus
20h 48m$105–198
Indianapolis (IND) to Columbia (CAE) flights
Questions & Answers
The cheapest way to get from Indianapolis to Orangeburg is to drive which costs $110 - $170 and takes 11h 35m.
The fastest way to get from Indianapolis to Orangeburg is to fly and taxi which takes 5h 51m and costs $190 - $600.
No, there is no direct bus from Indianapolis to Orangeburg. However, there are services departing from Indianapolis and arriving at Orangeburg via Atlanta Bus Station and Camden. The journey, including transfers, takes approximately 20h 28m.
The distance between Indianapolis and Orangeburg is 549 miles. The road distance is 625 miles.
The best way to get from Indianapolis to Orangeburg without a car is to train and bus which takes 19h 48m and costs $150 - $300.
It takes approximately 5h 51m to get from Indianapolis to Orangeburg, including transfers.
Indianapolis to Orangeburg bus services, operated by Flixbus USA, depart from Indianapolis station.
Indianapolis to Orangeburg bus services, operated by Flixbus USA, arrive at Atlanta Bus Station.
Yes, the driving distance between Indianapolis to Orangeburg is 625 miles. It takes approximately 11h 35m to drive from Indianapolis to Orangeburg.
Book your Indianapolis to Orangeburg bus tickets online with Omio.
What companies run services between Indianapolis, IN, USA and Orangeburg, SC, USA?
You can take a bus from Indianapolis to Orangeburg via Atlanta Bus Station, Camden, and Orangeburg in around 20h 28m.
- Website
- aa.com
Flights from Indianapolis to Columbia via Charlotte
- Ave. Duration
- 4h 19m
- When
- Every day
- Estimated price
- $75–430
Flights from Indianapolis to Columbia via Chicago O'Hare
- Ave. Duration
- 4h 30m
- When
- Every day
- Estimated price
- $100–550
Flights from Indianapolis to Columbia via New York La Guardia
- Ave. Duration
- 6h 31m
- When
- Every day
- Estimated price
- $130–650
Flights from Indianapolis to Columbia via Reagan Washington
- Ave. Duration
- 5h 25m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $100–550
Flights from Indianapolis to Columbia via Philadelphia
- Ave. Duration
- 6h 12m
- When
- Every day
- Estimated price
- $120–600
Flights from Indianapolis to Augusta Regional Airport At Bush Field via Charlotte
- Ave. Duration
- 4h 17m
- When
- Every day
- Estimated price
- $75–450
Flights from Indianapolis to Augusta Regional Airport At Bush Field via Dallas/Ft.Worth
- Ave. Duration
- 6h 46m
- When
- Every day
- Estimated price
- $160–750
Flights from Indianapolis to Augusta Regional Airport At Bush Field via Reagan Washington
- Ave. Duration
- 6h 59m
- When
- Saturday
- Estimated price
- $110–550
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Indianapolis to Ashland Amtrak Station
- Ave. Duration
- 6h 30m
- Frequency
- 3 times a week
- Estimated price
- $70–160
- Website
- Amtrak
- Phone
- +1 888-378-3823
- [email protected]
- Website
- Barons Bus
Bus from Ashland to Charlotte Bus Station
- Ave. Duration
- 7h 15m
- Frequency
- Once daily
- Estimated price
- $30–80
- Website
- Barons Bus
Bus from Columbus to Charlotte
- Ave. Duration
- 10h 20m
- Frequency
- Once daily
- Estimated price
- $45–100
- Website
- Barons Bus
- Ave. Duration
- 42 min
- Estimated price
- $120–150
Checker Yellow Cabs
- Phone
- +1 803-799-3311
- Website
- checkeryellowcab.com
Want to know more about travelling around United States
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More Questions & Answers
There are 22+ hotels available in Orangeburg.







