There are 7 ways to get from Indianapolis to Santa Ana by plane, bus (Greyhound), train (Amtrak), car, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to John Wayne Airport Orange County
best- Fly from Indianapolis (IND) to John Wayne Airport Orange County (SNA)plane IND - SNA
7h 55m$231–937Fly to Long Beach Airport
cheapest- Fly from Indianapolis (IND) to Long Beach Airport (LGB)plane IND - LGB
11h 6m$157–709Bus (Greyhound)
- Take the bus from Indianapolis Union Station to St Louis Bus Stationbus
- Take the bus from St Louis Bus Station to Montclair Transcenterbus
- Take the bus from Montclair Transcenter to Anaheim Regional Transportation Intermodal Centerbus
47h 33m$387–583Train (Amtrak)
- Take the train from Indianapolis to Chicago Union Stationtrain Cardinal
- Take the train from Chicago Union Station to Fullerton Amtrak Stationtrain Southwest Chief
2d 1h$1,314–2,074Drive 2,053.1 mi
- Drive from Indianapolis to Santa Anacar 2,053.1 mi
32h 32m$375–542Fly to Los Angeles International Airport, train
- Fly from Indianapolis (IND) to Los Angeles International Airport (LAX)plane IND - LAX
- Take the train from Los Angeles to Santa Anatrain
8h 58m$188–375Fly to San Diego International Airport, train
- Fly from Indianapolis (IND) to San Diego International Airport (SAN)plane IND - SAN
- Take the train from San Diego to Santa Anatrain
9h 42m$204–787
Indianapolis to Santa Ana by bus (Greyhound)
Comparing Your Travel Options
The cheapest way to get from Indianapolis to Santa Ana is to fly and train which costs $180 - $380 and takes 8h 58m.
The fastest way to get from Indianapolis to Santa Ana is to fly which takes 7h 55m and costs $230 - $950.
No, there is no direct bus from Indianapolis station to Santa Ana. However, there are services departing from Indianapolis Union Station and arriving at Main-1St via St Louis Bus Station, Montclair Transcenter and Artic - Dock 4. The journey, including transfers, takes approximately 47h 33m.
No, there is no direct train from Indianapolis to Santa Ana. However, there are services departing from Indianapolis and arriving at Santa Ana via Chicago Union Station and Fullerton Amtrak Station. The journey, including transfers, takes approximately 2 days 1h.
The distance between Indianapolis and Santa Ana is 1820 miles. The road distance is 2065.1 miles.
The best way to get from Indianapolis to Santa Ana without a car is to bus which takes 47h 33m and costs $380 - $600.
It takes approximately 7h 55m to get from Indianapolis to Santa Ana, including transfers.
Indianapolis to Santa Ana bus services, operated by Greyhound USA, depart from Indianapolis Union Station.
Indianapolis to Santa Ana train services, operated by Amtrak, depart from Indianapolis station.
The best way to get from Indianapolis to Santa Ana is to fly which takes 7h 55m and costs $230 - $950. Alternatively, you can bus, which costs $380 - $600 and takes 47h 33m, you could also train, which costs $1,300 - $2,100 and takes 2 days 1h.
What companies run services between Indianapolis, IN, USA and Santa Ana, CA, USA?
Southwest Airlines, American Airlines, and Delta fly from Indianapolis (IND) to John Wayne Airport Orange County (SNA) every 2 hours. Alternatively, you can take a bus from Indianapolis Union Station to Main-1St via St Louis Bus Station, Montclair Transcenter, Anaheim Regional Transportation Intermodal Center, and Artic - Dock 4 in around 47h 33m.
- Website
- southwest.com
Flights from Indianapolis to John Wayne Airport Orange County via Phoenix
- Ave. Duration
- 6h 43m
- When
- Monday to Wednesday
- Estimated price
- $200–900
Flights from Indianapolis to John Wayne Airport Orange County via Denver
- Ave. Duration
- 6h 36m
- When
- Every day
- Estimated price
- $200–900
Flights from Indianapolis to John Wayne Airport Orange County via Las Vegas
- Ave. Duration
- 6h 34m
- When
- Monday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $200–900
Flights from Indianapolis to Los Angeles International Airport via Las Vegas
- Ave. Duration
- 6h 15m
- When
- Monday, Thursday, Friday, and Saturday
- Estimated price
- $120–550
Flights from Indianapolis to Los Angeles International Airport via Denver
- Ave. Duration
- 6h 12m
- When
- Saturday, Monday, Thursday, and Friday
- Estimated price
- $120–550
Flights from Indianapolis to Los Angeles International Airport via Phoenix
- Ave. Duration
- 6h 16m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $120–550
Flights from Indianapolis to San Diego International Airport
- Ave. Duration
- 4h 25m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $150–700
Flights from Indianapolis to San Diego International Airport via Phoenix
- Ave. Duration
- 6h 14m
- When
- Every day
- Estimated price
- $150–700
Flights from Indianapolis to San Diego International Airport via Denver
- Ave. Duration
- 6h 7m
- When
- Monday to Saturday
- Estimated price
- $160–700
Flights from Indianapolis to San Diego International Airport via Las Vegas
- Ave. Duration
- 6h 18m
- When
- Tuesday, Wednesday, Monday, Thursday, Friday, and Sunday
- Estimated price
- $160–700
Flights from Indianapolis to Long Beach Airport via Las Vegas
- Ave. Duration
- 6h 30m
- When
- Tuesday to Saturday
- Estimated price
- $150–700
Flights from Indianapolis to Long Beach Airport via Denver
- Ave. Duration
- 7h 30m
- When
- Monday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $150–700
Flights from Indianapolis to Long Beach Airport via Phoenix
- Ave. Duration
- 6h 53m
- When
- Monday to Wednesday
- Estimated price
- $150–700
Flights from Indianapolis to Long Beach Airport via Austin
- Ave. Duration
- 9h 32m
- When
- Monday to Wednesday
- Estimated price
- $170–750
Flights from Indianapolis to Long Beach Airport via Chicago Midway
- Ave. Duration
- 8h 40m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $160–700
Flights from Indianapolis to Long Beach Airport via Dallas
- Ave. Duration
- 9h 5m
- When
- Monday, Thursday, and Friday
- Estimated price
- $160–750
- Website
- aa.com
Flights from Indianapolis to John Wayne Airport Orange County via Phoenix
- Ave. Duration
- 6h 49m
- When
- Every day
- Estimated price
- $200–900
Flights from Indianapolis to John Wayne Airport Orange County via Dallas/Ft.Worth
- Ave. Duration
- 7h 26m
- When
- Every day
- Estimated price
- $220–950
Flights from Indianapolis to Los Angeles International Airport
- Ave. Duration
- 4h 38m
- When
- Every day
- Estimated price
- $120–550
- Website
- delta.com
Flights from Indianapolis to John Wayne Airport Orange County via Minneapolis
- Ave. Duration
- 7h 23m
- When
- Every day
- Estimated price
- $220–950
Flights from Indianapolis to Los Angeles International Airport
- Ave. Duration
- 4h 29m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $120–550
Flights from Indianapolis to Long Beach Airport via Salt Lake City
- Ave. Duration
- 8h 4m
- When
- Every day
- Estimated price
- $160–700
- Website
- united.com
Flights from Indianapolis to Los Angeles International Airport via Denver
- Ave. Duration
- 6h 29m
- When
- Every day
- Estimated price
- $120–550
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Indianapolis to Chicago Union Station
- Ave. Duration
- 5h
- Frequency
- 3 times a week
- Estimated price
- $100–170
- Website
- Amtrak
Train from Chicago Union Station to Fullerton Amtrak Station
- Ave. Duration
- 42h 44m
- Frequency
- Once daily
- Estimated price
- $1,200–1,900
- Website
- Amtrak
Train from Los Angeles to Santa Ana
- Ave. Duration
- 50 min
- Frequency
- Hourly
- Estimated price
- $19–30
- Website
- Amtrak
Train from San Diego to Santa Ana
- Ave. Duration
- 2h 1m
- Frequency
- Hourly
- Estimated price
- $50–80
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Indianapolis Union Station to St Louis Bus Station
- Ave. Duration
- 3h 55m
- Frequency
- 3 times a day
- Estimated price
- $40–65
- Website
- Greyhound
Bus from St Louis Bus Station to Montclair Transcenter
- Ave. Duration
- 39h 35m
- Frequency
- Once daily
- Estimated price
- $330–500
- Website
- Greyhound
Bus from Montclair Transcenter to Anaheim Regional Transportation Intermodal Center
- Ave. Duration
- 1h 30m
- Frequency
- Once daily
- Estimated price
- $11–17
- Website
- Greyhound
Want to know more about travelling around United States
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Booking & Getting There
Indianapolis to Santa Ana bus services, operated by Greyhound USA, arrive at St Louis Bus Station.
Santa Ana is 3h behind Indianapolis. It is currently 7:20 PM in Indianapolis and 4:20 PM in Santa Ana.
Indianapolis to Santa Ana train services, operated by Amtrak, arrive at Chicago Union Station.
Yes, the driving distance between Indianapolis to Santa Ana is 2065 miles. It takes approximately 32h 32m to drive from Indianapolis to Santa Ana.
Book your Indianapolis to Santa Ana train tickets online with Omio.
Book your Indianapolis to Santa Ana bus tickets online with Omio.
There are 1593+ hotels available in Santa Ana.





