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How to get fromIndianapolis to Santa Anaby plane, bus (Greyhound), bus, train, or car

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There are 7 ways to get from Indianapolis to Santa Ana by plane, bus (Greyhound), bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to John Wayne Airport Orange County

    best
    1. Fly from Indianapolis (IND) to John Wayne Airport Orange County (SNA)plane plane IND - SNA
    7h 45m
    $251–987

  2. Fly to Los Angeles International Airport, train

    cheapest
    1. Fly from Indianapolis (IND) to Los Angeles International Airport (LAX)plane plane IND - LAX
    2. Take the train from Los Angeles to Santa Anatrain train
    8h 52m
    $150–488

  3. Bus

    1. Take the bus from Indianapolis Union Station to St Louis Bus Stationbus bus
    2. Take the bus from St Louis Bus Station to El Monte Bus Stopbus bus
    3. Take the bus from El Monte Station - Lower Level to 7th / Channelbus bus 577
    2d
    $333–626

  4. Bus, train

    1. Take the bus from Indianapolis to Chicago Bus Stationbus bus FlixBus 2511 / ...
    2. Take the train from Chicago Union Station to Fullerton Amtrak Stationtrain train Southwest Chief
    2d
    $732–1,550

  5. Drive 2,053.1 mi

    1. Drive from Indianapolis to Santa Anacar car 2,053.1 mi
    32h 32m
    $375–542

  6. Fly to San Diego International Airport, train

    1. Fly from Indianapolis (IND) to San Diego International Airport (SAN)plane plane IND - SAN
    2. Take the train from San Diego to Santa Anatrain train
    9h 32m
    $244–967

  7. Fly to Long Beach Airport

    1. Fly from Indianapolis (IND) to Long Beach Airport (LGB)plane plane IND - LGB
    10h 50m
    $187–810

Indianapolis to Santa Ana by bus

Calendar7Weekly Buses
Duration2dAverage Duration
Ticket$333Cheapest Price
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Questions & Answers

Map of how to get from Indianapolis to Santa Ana.ExpandLaunch map view
  • Distance: 1,809.2 mi
  • Duration: 7h 45m

What companies run services between Indianapolis, IN, USA and Santa Ana, CA, USA?

Southwest Airlines, United Airlines, and two other airlines fly from Indianapolis (IND) to John Wayne Airport Orange County (SNA) every 2 hours. Alternatively, you can take a bus from Indianapolis Union Station to Main-Civic Center via St Louis Bus Station, El Monte Station - Lower Level, 7th / Channel, 7Th-Channel, and Katella-Harbor in around 2d.

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