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How to get fromIndianapolis to Senecaby plane, taxi, bus, car, or train

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There are 8 ways to get from Indianapolis to Seneca by plane, taxi, bus, car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Indianapolis to Greenville–Spartanburg International Airport, taxi

    best
    1. Fly from Indianapolis (IND) to Greenville–Spartanburg International Airport (GSP)plane plane IND - GSP
    2. Take the taxi from Greenville–Spartanburg International Airport (GSP) to Senecataxi taxi
    6h 18m
    $227–772

  2. Drive  497.5 mi

    cheapest
    1. Drive from Indianapolis to Senecacar car 497.5 mi
    10h
    $85–123

  3. Bus, taxi

    1. Take the bus from Indianapolis Union Station to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta to Flying J - Commercebus bus
    3. Take the taxi from Flying J - Commerce to Senecataxi taxi
    15h 49m
    $218–317

  4. Fly Indianapolis to Asheville Regional Airport, drive

    1. Fly from Indianapolis (IND) to Asheville Regional Airport (AVL)plane plane IND - AVL
    2. Drive from Asheville-Airport-AVL to Senecacar car
    7h 24m
    $89–460

  5. Bus to Covington, fly to Greenville–Spartanburg International Airport, taxi

    1. Take the bus from Indianapolis to Cincinnatibus bus
    2. Fly from Covington (CVG) to Greenville–Spartanburg International Airport (GSP)plane plane CVG - GSP
    3. Take the taxi from Greenville–Spartanburg International Airport (GSP) to Senecataxi taxi
    6h 45m
    $280–1,001

  6. Fly Indianapolis to Hartsfield-Jackson Atlanta International Airport, bus, taxi

    1. Fly from Indianapolis (IND) to Hartsfield-Jackson Atlanta International Airport (ATL)plane plane IND - ATL
    2. Take the bus from Atlanta to Flying J - Commercebus bus
    3. Take the taxi from Flying J - Commerce to Senecataxi taxi
    7h 55m
    $252–405

  7. Fly Indianapolis to Charlotte Douglas International Airport, train

    1. Fly from Indianapolis (IND) to Charlotte Douglas International Airport (CLT)plane plane IND - CLT
    2. Take the train from Charlotte Amtrak Station to Clemson Amtrak Stationtrain train
    8h 58m
    $205–808

  8. Bus, taxi via Atlanta

    1. Take the bus from Indianapolis to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta to Flying J - Commercebus bus
    3. Take the taxi from Flying J - Commerce to Senecataxi taxi
    16h 5m
    $215–310

Indianapolis (IND) to Greenville–Spartanburg International Airport (GSP) flights

Calendar132Weekly Planes
Duration4h 19mAverage Duration
Ticket$98Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from Indianapolis to Seneca.ExpandLaunch map view
  • Distance: 465.3 mi
  • Duration: 6h 18m

What companies run services between Indianapolis, IN, USA and Seneca, SC, USA?

There is no direct connection from Indianapolis to Seneca. However, you can take the line 8 bus to Indianapolis Airport, walk to Indianapolis (IND) airport, fly to Greenville–Spartanburg International Airport (GSP), then take the taxi to Seneca. Alternatively, you can take the bus to Atlanta Bus Station, walk to Garnett Station, take the subway to Doraville Station, walk to Atlanta, take the bus to Flying J - Commerce, then take the taxi to Seneca.

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