There are 7 ways to get from Indianapolis to Seneca by plane, taxi, bus, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Indianapolis to Greenville–Spartanburg International Airport, taxi
best- Fly from Indianapolis (IND) to Greenville–Spartanburg International Airport (GSP)plane IND - GSP
- Take the taxi from Greenville–Spartanburg International Airport (GSP) to Senecataxi
6h 13m$242–822Fly Indianapolis to Asheville Regional Airport, drive
cheapest- Fly from Indianapolis (IND) to Asheville Regional Airport (AVL)plane IND - AVL
- Drive from Asheville-Airport-AVL to Senecacar
7h 16m$89–451Bus, taxi via Atlanta
- Take the bus from Indianapolis to Atlanta Bus Stationbus
- Take the bus from Atlanta to Flying J - Commercebus
- Take the taxi from Flying J - Commerce to Senecataxi
14h 35m$269–445Drive 497.5 mi
- Drive from Indianapolis to Senecacar 497.5 mi
10h$91–132Bus to Covington, fly to Greenville–Spartanburg International Airport, taxi
- Take the bus from Indianapolis to Cincinnatibus
- Fly from Covington (CVG) to Greenville–Spartanburg International Airport (GSP)plane CVG - GSP
- Take the taxi from Greenville–Spartanburg International Airport (GSP) to Senecataxi
6h 45m$298–974Fly Indianapolis to Hartsfield-Jackson Atlanta International Airport, bus, taxi
- Fly from Indianapolis (IND) to Hartsfield-Jackson Atlanta International Airport (ATL)plane IND - ATL
- Take the bus from Atlanta to Flying J - Commercebus
- Take the taxi from Flying J - Commerce to Senecataxi
7h 52m$385–1,275Bus, taxi
- Take the bus from Indianapolis Union Station to Atlanta Bus Stationbus
- Take the bus from Atlanta to Flying J - Commercebus
- Take the taxi from Flying J - Commerce to Senecataxi
15h 47m$266–442
Indianapolis (IND) to Greenville–Spartanburg International Airport (GSP) flights
Questions & Answers
The cheapest way to get from Indianapolis to Seneca is to drive which costs $90 - $140 and takes 10h.
The fastest way to get from Indianapolis to Seneca is to fly and taxi which takes 6h 13m and costs $240 - $850.
The distance between Indianapolis and Seneca is 470 miles. The road distance is 500.4 miles.
The best way to get from Indianapolis to Seneca without a car is to bus and taxi via Atlanta which takes 14h 35m and costs $260 - $450.
It takes approximately 6h 13m to get from Indianapolis to Seneca, including transfers.
Yes, the driving distance between Indianapolis to Seneca is 500 miles. It takes approximately 10h to drive from Indianapolis to Seneca.
There are 167+ hotels available in Seneca.
What companies run services between Indianapolis, IN, USA and Seneca, SC, USA?
There is no direct connection from Indianapolis to Seneca. However, you can take the line 8 bus to Indianapolis Airport, walk to Indianapolis (IND) airport, fly to Greenville–Spartanburg International Airport (GSP), then take the taxi to Seneca. Alternatively, you can take the bus to Atlanta Bus Station, walk to Garnett Station, take the subway to Lindbergh Center Station, walk to Lindbergh Center Station - Bay D, take the line 39 bus to Shallowford Rd @ New Peachtree, walk to Atlanta, take the bus to Flying J - Commerce, then take the taxi to Seneca.
- Website
- delta.com
Flights from Indianapolis to Greenville–Spartanburg International Airport via Hartsfield-Jackson Atlanta International Airport
- Ave. Duration
- 4h 1m
- When
- Every day
- Estimated price
- $120–700
Flights from Indianapolis to Greenville–Spartanburg International Airport via Detroit
- Ave. Duration
- 3h 57m
- When
- Every day
- Estimated price
- $140–750
Flights from Indianapolis to Asheville Regional Airport via Hartsfield-Jackson Atlanta International Airport
- Ave. Duration
- 4h 26m
- When
- Every day
- Estimated price
- $85–450
Flights from Covington to Greenville–Spartanburg International Airport via Hartsfield-Jackson Atlanta International Airport
- Ave. Duration
- 3h 30m
- When
- Every day
- Estimated price
- $130–750
Flights from Indianapolis to Hartsfield-Jackson Atlanta International Airport
- Ave. Duration
- 1h 39m
- When
- Every day
- Estimated price
- $90–550
- Website
- southwest.com
Flights from Indianapolis to Greenville–Spartanburg International Airport via Nashville
- Ave. Duration
- 4h 1m
- When
- Tuesday, Wednesday, Monday, Thursday, Friday, and Sunday
- Estimated price
- $110–650
Flights from Indianapolis to Greenville–Spartanburg International Airport via Baltimore
- Ave. Duration
- 4h 20m
- When
- Sunday and Saturday
- Estimated price
- $170–850
Flights from Covington to Greenville–Spartanburg International Airport via Nashville
- Ave. Duration
- 3h 23m
- When
- Sunday, Tuesday, Wednesday, Monday, Thursday, and Friday
- Estimated price
- $130–750
Flights from Indianapolis to Hartsfield-Jackson Atlanta International Airport
- Ave. Duration
- 1h 30m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $90–550
Flights from Indianapolis to Hartsfield-Jackson Atlanta International Airport via Nashville
- Ave. Duration
- 3h 25m
- When
- Tuesday to Friday
- Estimated price
- $95–550
Flights from Indianapolis to Hartsfield-Jackson Atlanta International Airport via Chicago Midway
- Ave. Duration
- 3h 51m
- When
- Saturday to Friday
- Estimated price
- $130–650
- Website
- aa.com
Flights from Indianapolis to Greenville–Spartanburg International Airport via Charlotte
- Ave. Duration
- 4h 8m
- When
- Every day
- Estimated price
- $110–650
Flights from Indianapolis to Asheville Regional Airport via Charlotte
- Ave. Duration
- 4h
- When
- Every day
- Estimated price
- $75–430
Flights from Indianapolis to Asheville Regional Airport via Chicago O'Hare
- Ave. Duration
- 5h 39m
- When
- Every day
- Estimated price
- $95–480
Flights from Indianapolis to Hartsfield-Jackson Atlanta International Airport via Charlotte
- Ave. Duration
- 3h 48m
- When
- Tuesday
- Estimated price
- $110–600
- Website
- united.com
Flights from Indianapolis to Greenville–Spartanburg International Airport via Washington Dulles
- Ave. Duration
- 4h 20m
- When
- Every day
- Estimated price
- $160–800
Flights from Indianapolis to Greenville–Spartanburg International Airport via Chicago O'Hare
- Ave. Duration
- 4h 35m
- When
- Every day
- Estimated price
- $140–750
Flights from Indianapolis to Asheville Regional Airport via Chicago O'Hare
- Ave. Duration
- 4h 37m
- When
- Every day
- Estimated price
- $95–480
- Website
- flybreeze.com
Flights from Covington to Greenville–Spartanburg International Airport
- Ave. Duration
- 1h 17m
- When
- Monday and Friday
- Estimated price
- $260–1,800
- Website
- flyfrontier.com
Flights from Indianapolis to Hartsfield-Jackson Atlanta International Airport
- Ave. Duration
- 1h 47m
- When
- Monday, Wednesday, and Friday
- Estimated price
- $170–650
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from Indianapolis to Atlanta Bus Station
- Ave. Duration
- 9h 55m
- Frequency
- Twice daily
- Estimated price
- $120–170
- Book at
- https://www.jeffersonlines.com
- Adult
- $120–170
Bus from Indianapolis to Cincinnati
- Ave. Duration
- 2h
- Frequency
- Once daily
- Estimated price
- $35–50
- Book at
- https://www.jeffersonlines.com
- Adult
- $35–50
Bus from Indianapolis Union Station to Atlanta Bus Station
- Ave. Duration
- 11h 25m
- Frequency
- 3 times a day
- Estimated price
- $120–170
- Book at
- https://www.jeffersonlines.com
- Adult
- $120–170
- Phone
- +1 888 358 6762
- [email protected]
- Website
- tornadobus.com
Bus from Atlanta to Flying J - Commerce
- Ave. Duration
- 1h 52m
- Frequency
- Once daily
- Estimated price
- $40–140
- Schedules at
- tornadobus.com
- Adults 11-59
- $40–140
Bus from Atlanta to Flying J - Commerce
- Ave. Duration
- 1h 52m
- Frequency
- Once daily
- Estimated price
- $40–140
- Schedules at
- tornadobus.com
- Adults 11-59
- $40–140
Bus from Atlanta to Flying J - Commerce
- Ave. Duration
- 1h 52m
- Frequency
- Once daily
- Estimated price
- $40–140
- Schedules at
- tornadobus.com
- Adults 11-59
- $40–140
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- greyhound.com
Bus from Indianapolis Union Station to Atlanta Bus Station
- Ave. Duration
- 11h 25m
- Frequency
- 4 times a day
- Estimated price
- $85–170
- Website
- https://www.greyhound.com/
- Ave. Duration
- 54 min
- Estimated price
- $100–170
GVL Taxi
- Phone
- +1 864-920-3352
- Website
- gvltaxi.com
Personal Touch Transportation
- Phone
- +18645250420
Yellow Cab Greenville
- Phone
- +1 864-233-6666
- Website
- yellowcabgreenville.com
Checker Cab
- Phone
- +1 864-583-2721
GVL Taxi
- Phone
- +1 864-920-3352
- Website
- gvltaxi.com
Personal Touch Transportation
- Phone
- +18645250420
Yellow Cab Greenville
- Phone
- +1 864-233-6666
- Website
- yellowcabgreenville.com
Checker Cab
- Phone
- +1 864-583-2721
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide







