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How to get fromIndianapolis to Sikestonby bus, taxi, train, car, plane, or bus (Greyhound)

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There are 7 ways to get from Indianapolis to Sikeston by bus, taxi, train, car, plane, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus, taxi

    best
    1. Take the bus from Indianapolis Union Station to St Louis Bus Stationbus bus
    2. Take the bus from St Louis Bus Station to Cape Girardeaubus bus
    3. Take the taxi from Cape Girardeau to Sikestontaxi taxi
    7h 35m
    $141–220

  2. Drive 327.6 mi

    cheapest
    1. Drive from Indianapolis to Sikestoncar car 327.6 mi
    5h 24m
    $60–87

  3. Bus, train, drive

    1. Take the bus from Indianapolis Union Station to Champaign Intermodal Trans Ctrbus bus
    2. Take the train from Champaign-Urbana to Fulton Amtrak Stationtrain train
    3. Drive from Fulton Amtrak Station to Sikestoncar car
    9h 31m
    $104–221

  4. Fly to Barkley Regional Airport, drive

    1. Fly from Indianapolis (IND) to Barkley Regional Airport (PAH)plane plane IND - PAH
    2. Drive from Barkley Regional Airport (PAH) to Sikestoncar car
    7h 46m
    $82–437

  5. Bus

    1. Take the bus from Indianapolis Union Station to Champaign Intermodal Trans Ctrbus bus Greyhound US0157S
    2. Take the bus from Road Ranger Truck Stop - Champaign to Flying J - Matthewsbus bus Milwaukee
    8h 28m
    $115–164

  6. Fly to Williamson County Regional Airport, bus

    1. Fly from Indianapolis (IND) to Williamson County Regional Airport (MWA)plane plane IND - MWA
    2. Take the bus from Marathon Gas Station - Marion to Flying J - Matthewsbus bus
    8h 34m
    $127–513

  7. Fly to Nashville, bus, drive

    1. Fly from Indianapolis (IND) to Nashville (BNA)plane plane IND - BNA
    2. Take the bus from Nashville Bus Station to Paducah Bus Stationbus bus
    3. Drive from Paducah Bus Station to Sikestoncar car
    8h 22m
    $343–1,156

Indianapolis (IND) to Barkley Regional Airport (PAH) flights

Calendar15Weekly Planes
Duration6h 49mAverage Duration
Ticket$74Cheapest Price
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Questions & Answers

Map of how to get from Indianapolis to Sikeston.ExpandLaunch map view
  • Distance: 388.4 mi
  • Duration: 7h 35m

What companies run services between Indianapolis, IN, USA and Sikeston, MO, USA?

You can take a bus from Indianapolis Union Station to Sikeston via Champaign Intermodal Trans Ctr, Road Ranger Truck Stop - Champaign, and Flying J - Matthews in around 8h 28m.

Airlines
Train operators
Bus operators
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