There are 7 ways to get from Indianapolis to Spartanburg by plane, bus (Flixbus, Greyhound), train (Amtrak), car, train, or bus (Flixbus)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Greenville–Spartanburg International Airport
best- Fly from Indianapolis (IND) to Greenville–Spartanburg International Airport (GSP)plane IND - GSP
5h 23m$167–772Fly to Asheville Regional Airport, drive
cheapest- Fly from Indianapolis (IND) to Asheville Regional Airport (AVL)plane IND - AVL
- Drive from Asheville-Airport-AVL to Spartanburgcar
6h 22m$86–457Bus
- Take the bus from Indianapolis to Atlanta Bus Stationbus FlixBus 2512
- Take the bus from Atlanta Bus Station to Spartanburgbus Greyhound US0670
15h 10m$131–196Train (Amtrak)
- Take the train from Indianapolis to Charlottesvilletrain Cardinal
- Take the train from Charlottesville to Spartanburg Stationtrain Crescent
23h 49m$516–805Drive 493.4 mi
- Drive from Indianapolis to Spartanburgcar 493.4 mi
9h 32m$91–131Fly to Charlotte Douglas International Airport, train
- Fly from Indianapolis (IND) to Charlotte Douglas International Airport (CLT)plane IND - CLT
- Take the train from Charlotte Amtrak Station to Spartanburg Stationtrain
7h 2m$146–723Bus via Sandy Springs
- Take the bus from Indianapolis to Atlanta Bus Stationbus FlixBus 2512
- Take the bus from Atlanta to Servicios Zapata - Spartanburgbus Charlotte
17h 4m$137–207
Indianapolis to Spartanburg by train (Amtrak)
Comparing Your Travel Options
The cheapest way to get from Indianapolis to Spartanburg is to drive which costs $90 - $130 and takes 9h 32m.
The fastest way to get from Indianapolis to Spartanburg is to fly which takes 5h 23m and costs $160 - $800.
No, there is no direct bus from Indianapolis to Spartanburg. However, there are services departing from Indianapolis and arriving at Spartanburg via Atlanta Bus Station. The journey, including transfers, takes approximately 15h 10m.
No, there is no direct train from Indianapolis to Spartanburg station. However, there are services departing from Indianapolis and arriving at Spartanburg Station via Charlottesville. The journey, including transfers, takes approximately 23h 49m.
The distance between Indianapolis and Spartanburg is 439 miles. The road distance is 496.3 miles.
The best way to get from Indianapolis to Spartanburg without a car is to bus which takes 15h 10m and costs $130 - $200.
It takes approximately 5h 23m to get from Indianapolis to Spartanburg, including transfers.
Indianapolis to Spartanburg bus services, operated by Flixbus USA, depart from Indianapolis station.
Indianapolis to Spartanburg train services, operated by Amtrak, depart from Indianapolis station.
The best way to get from Indianapolis to Spartanburg is to fly which takes 5h 23m and costs $160 - $800. Alternatively, you can bus, which costs $130 - $200 and takes 15h 10m, you could also train, which costs $500 - $850 and takes 23h 49m.
What companies run services between Indianapolis, IN, USA and Spartanburg, SC, USA?
Southwest Airlines, American Airlines, and two other airlines fly from Indianapolis (IND) to Greenville–Spartanburg International Airport (GSP) hourly. Alternatively, you can take a bus from Indianapolis to Spartanburg via Atlanta Bus Station and Spartanburg in around 15h 10m.
- Website
- aa.com
Flights from Indianapolis to Greenville–Spartanburg International Airport via Charlotte Douglas International Airport
- Ave. Duration
- 4h 13m
- When
- Every day
- Estimated price
- $110–700
Flights from Indianapolis to Greenville–Spartanburg International Airport via Chicago O'Hare
- Ave. Duration
- 4h 22m
- When
- Every day
- Estimated price
- $140–800
Flights from Indianapolis to Asheville Regional Airport via Charlotte Douglas International Airport
- Ave. Duration
- 4h 10m
- When
- Every day
- Estimated price
- $75–440
Flights from Indianapolis to Asheville Regional Airport via Chicago O'Hare
- Ave. Duration
- 4h 43m
- When
- Every day
- Estimated price
- $90–490
Flights from Indianapolis to Asheville Regional Airport via Philadelphia
- Ave. Duration
- 5h 11m
- When
- Every day
- Estimated price
- $110–600
Flights from Indianapolis to Charlotte Douglas International Airport
- Ave. Duration
- 1h 46m
- When
- Every day
- Estimated price
- $100–650
- Website
- delta.com
Flights from Indianapolis to Greenville–Spartanburg International Airport via Atlanta
- Ave. Duration
- 4h 22m
- When
- Every day
- Estimated price
- $120–750
Flights from Indianapolis to Greenville–Spartanburg International Airport via Detroit
- Ave. Duration
- 4h 28m
- When
- Every day
- Estimated price
- $140–800
Flights from Indianapolis to Asheville Regional Airport via Atlanta
- Ave. Duration
- 4h 8m
- When
- Every day
- Estimated price
- $80–460
Flights from Indianapolis to Charlotte Douglas International Airport via Detroit
- Ave. Duration
- 4h 1m
- When
- Every day
- Estimated price
- $130–750
Flights from Indianapolis to Charlotte Douglas International Airport via Atlanta
- Ave. Duration
- 4h 2m
- When
- Every day
- Estimated price
- $120–700
- Website
- united.com
Flights from Indianapolis to Greenville–Spartanburg International Airport via Chicago O'Hare
- Ave. Duration
- 4h 33m
- When
- Every day
- Estimated price
- $140–800
Flights from Indianapolis to Greenville–Spartanburg International Airport via Washington Dulles
- Ave. Duration
- 4h 16m
- When
- Saturday, Monday, Thursday, Friday, and Sunday
- Estimated price
- $160–850
Flights from Indianapolis to Asheville Regional Airport via Chicago O'Hare
- Ave. Duration
- 4h 44m
- When
- Every day
- Estimated price
- $90–490
- Website
- southwest.com
Flights from Indianapolis to Greenville–Spartanburg International Airport via Nashville
- Ave. Duration
- 3h 17m
- When
- Sunday, Monday, Thursday, and Friday
- Estimated price
- $120–700
Flights from Indianapolis to Greenville–Spartanburg International Airport via Baltimore
- Ave. Duration
- 4h 16m
- When
- Tuesday, Wednesday, Monday, Thursday, Friday, and Sunday
- Estimated price
- $170–850
Flights from Indianapolis to Charlotte Douglas International Airport via Nashville
- Ave. Duration
- 3h 21m
- When
- Saturday, Sunday, Monday, Thursday, and Friday
- Estimated price
- $110–700
Flights from Indianapolis to Charlotte Douglas International Airport via Chicago Midway
- Ave. Duration
- 3h 50m
- When
- Monday, Thursday, Friday, and Saturday
- Estimated price
- $130–750
- Website
- allegiantair.com
Flights from Indianapolis to Asheville Regional Airport via Orlando Sanford
- Ave. Duration
- 5h 51m
- When
- Saturday
- Estimated price
- $130–650
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Indianapolis to Charlottesville
- Ave. Duration
- 15h 20m
- Frequency
- 3 times a week
- Estimated price
- $330–550
- Website
- Amtrak
Train from Charlottesville to Spartanburg Station
- Ave. Duration
- 7h 29m
- Frequency
- Once daily
- Estimated price
- $180–290
- Website
- Amtrak
Train from Charlotte Amtrak Station to Spartanburg Station
- Ave. Duration
- 1h 26m
- Frequency
- Once daily
- Estimated price
- $40–65
- Website
- Amtrak
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Indianapolis to Atlanta Bus Station
- Ave. Duration
- 11h 5m
- Frequency
- Twice daily
- Estimated price
- $85–130
- Schedules at
- Flixbus USA
Bus from Indianapolis to Atlanta Bus Station
- Ave. Duration
- 11h 5m
- Frequency
- Twice daily
- Estimated price
- $85–130
- Schedules at
- Flixbus USA
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Atlanta Bus Station to Spartanburg
- Ave. Duration
- 2h 55m
- Frequency
- 3 times a day
- Estimated price
- $30–50
- Website
- Greyhound
- Phone
- +1 888 358 6762
- [email protected]
- Website
- Tornado Bus Company
Bus from Atlanta to Servicios Zapata - Spartanburg
- Ave. Duration
- 4h 4m
- Frequency
- Once daily
- Estimated price
- $35–60
- Schedules at
- Tornado Bus Company
- Adult
- $35–60
Want to know more about travelling around United States
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Booking & Getting There
Indianapolis to Spartanburg bus services, operated by Flixbus USA, arrive at Atlanta Bus Station.
Indianapolis to Spartanburg train services, operated by Amtrak, arrive at Charlottesville station.
Yes, the driving distance between Indianapolis to Spartanburg is 496 miles. It takes approximately 9h 32m to drive from Indianapolis to Spartanburg.
Book your Indianapolis to Spartanburg train tickets online with Omio.
Book your Indianapolis to Spartanburg bus tickets online with Omio.
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