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How to get fromIndianapolis to Spartanburgby plane, bus, train (Amtrak), car, train, or bus (Greyhound)

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There are 8 ways to get from Indianapolis to Spartanburg by plane, bus, train (Amtrak), car, train, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Indianapolis to Greenville–Spartanburg International Airport

    best
    1. Fly from Indianapolis (IND) to Greenville–Spartanburg International Airport (GSP)plane plane IND - GSP
    5h 33m
    $167–722

  2. Fly Indianapolis to Asheville Regional Airport, drive

    cheapest
    1. Fly from Indianapolis (IND) to Asheville Regional Airport (AVL)plane plane IND - AVL
    2. Drive from Asheville-Airport-AVL to Spartanburgcar car
    6h 25m
    $86–447

  3. Bus

    1. Take the bus from Indianapolis to Atlanta Bus Stationbus bus FlixBus 2512
    2. Take the bus from Atlanta Bus Station to Spartanburgbus bus Greyhound US0670
    13h 59m

  4. Train (Amtrak)

    1. Take the train from Indianapolis to Charlottesvilletrain train Cardinal
    2. Take the train from Charlottesville to Spartanburg Stationtrain train Crescent
    23h 49m
    $308–625

  5. Drive 493.4 mi

    1. Drive from Indianapolis to Spartanburgcar car 493.4 mi
    9h 32m
    $91–131

  6. Bus to Covington, fly to Greenville–Spartanburg International Airport

    1. Take the bus from Indianapolis to Cincinnatibus bus
    2. Fly from Covington (CVG) to Greenville–Spartanburg International Airport (GSP)plane plane CVG - GSP
    6h 5m

  7. Fly Indianapolis to Charlotte Douglas International Airport, train

    1. Fly from Indianapolis (IND) to Charlotte Douglas International Airport (CLT)plane plane IND - CLT
    2. Take the train from Charlotte Amtrak Station to Spartanburg Stationtrain train
    7h 5m
    $130–708

  8. Bus via Sandy Springs

    1. Take the bus from Indianapolis Union Station to Atlanta Bus Stationbus bus Greyhound US0100
    2. Take the bus from Atlanta to Servicios Zapata - Spartanburgbus bus Charlotte
    17h 22m
    $149–327

Indianapolis to Spartanburg by train (Amtrak)

Calendar3Weekly Trains
Duration23h 49mAverage Duration
Ticket$308Cheapest Price
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Questions & Answers

Map of how to get from Indianapolis to Spartanburg.ExpandLaunch map view
  • Distance: 436.5 mi
  • Duration: 5h 33m

What companies run services between Indianapolis, IN, USA and Spartanburg, SC, USA?

Southwest Airlines, American Airlines, and two other airlines fly from Indianapolis (IND) to Greenville–Spartanburg International Airport (GSP) hourly. Alternatively, you can take a bus from Indianapolis to Spartanburg via Atlanta Bus Station and Spartanburg in around 13h 59m.

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