There are 11 ways to get from Indianapolis to Wytheville by train, bus, car, plane, bus (Greyhound), or shuttle
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train, bus
best- Take the train from Indianapolis to Ashland Amtrak Stationtrain Cardinal
- Take the bus from Ashland to Wythevillebus Columbus
12h 19m$130–265Drive 429.3 mi
cheapest- Drive from Indianapolis to Wythevillecar 429.3 mi
7h 34m$79–114Bus via Columbus
- Take the bus from Indianapolis to Columbusbus FlixBus N2640 / ...
- Take the bus from Columbus - Mound St to Wythevillebus Columbus
12h 33mFly to Charlotte Douglas International Airport, bus
- Fly from Indianapolis (IND) to Charlotte Douglas International Airport (CLT)plane IND - CLT
- Take the bus from Charlotte Bus Station to Max Meadowsbus
7h 31m$162–743Bus
- Take the bus from Indianapolis Union Station to Wilson & Ferrell Shell Station - Columbusbus Greyhound US0421
- Take the bus from Columbus to Wythevillebus Bsb 32
12h 48mFly to Roanoke Regional Airport-Woodrum Field, bus
- Fly from Indianapolis (IND) to Roanoke Regional Airport-Woodrum Field (ROA)plane IND - ROA
- Take the bus from Airport to Exit 118 - Park and Ridebus
- Take the bus from Route 460 Park and Ride to Rural King Shopping Centerbus
9h 28m$98–492Fly to Washington Dulles International Airport, bus
- Fly from Indianapolis (IND) to Washington Dulles International Airport (IAD)plane IND - IAD
- Take the bus from Dulles Airport to Rural King Shopping Centerbus
9h 52m$107–477Fly to Tri-Cities Regional Tn/Va Airport, shuttle, bus
- Fly from Indianapolis (IND) to Tri-Cities Regional Tn/Va Airport (TRI)plane IND - TRI
- Take a shuttle bus from Black Bear Resort to Low Gap
- Take the bus from Park and Ride Lot at I-81 Exit 5 to Rural King Shopping Centerbus
11h 19m$317–807Fly to Concord, bus
- Fly from Indianapolis (IND) to Concord (USA)plane IND - USA
- Take the bus from Charlotte Bus Station to Max Meadowsbus
6h 48m$378–1,017Fly to Raleigh-Durham International Airport, bus
- Fly from Indianapolis (IND) to Raleigh-Durham International Airport (RDU)plane IND - RDU
- Take the bus from Durham to Winston Salem(Trans Center)bus
- Take the bus from Winston Salem(Trans Center) to Wythevillebus
10h 11m$135–580Fly to Ronald Reagan Washington National Airport, bus
- Fly from Indianapolis (IND) to Ronald Reagan Washington National Airport (DCA)plane IND - DCA
- Take the bus from Dulles Airport to Rural King Shopping Centerbus
11h 6m$991–1,673
Indianapolis (IND) to Charlotte Douglas International Airport (CLT) flights
Questions & Answers
The cheapest way to get from Indianapolis to Wytheville is to drive which costs $75 - $120 and takes 7h 34m.
The fastest way to get from Indianapolis to Wytheville is to fly and bus which takes 6h 48m and costs $370 - $1,100.
No, there is no direct bus from Indianapolis to Wytheville. However, there are services departing from Indianapolis and arriving at Wytheville via S 3Rd St & E Town St and Columbus - Mound St. The journey, including transfers, takes approximately 12h 33m.
The distance between Indianapolis and Wytheville is 483 miles. The road distance is 431.8 miles.
The best way to get from Indianapolis to Wytheville without a car is to train and bus which takes 12h 19m and costs $130 - $270.
It takes approximately 12h 19m to get from Indianapolis to Wytheville, including transfers.
Indianapolis to Wytheville bus services, operated by FlixBus-us, depart from Indianapolis station.
Indianapolis to Wytheville bus services, operated by FlixBus-us, arrive at Columbus station.
Yes, the driving distance between Indianapolis to Wytheville is 432 miles. It takes approximately 7h 34m to drive from Indianapolis to Wytheville.
Book your Indianapolis to Wytheville bus tickets online with Omio.
What companies run services between Indianapolis, IN, USA and Wytheville, VA, USA?
You can take a bus from Indianapolis to Wytheville via Columbus, S 3Rd St & E Town St, E Livingston Ave & Macon Aly, Columbus - Mound St, and Wytheville in around 12h 33m.
- Website
- aa.com
Flights from Indianapolis to Charlotte Douglas International Airport
- Ave. Duration
- 1h 45m
- When
- Every day
- Estimated price
- $100–650
Flights from Indianapolis to Roanoke Regional Airport-Woodrum Field via Charlotte Douglas International Airport
- Ave. Duration
- 4h 25m
- When
- Every day
- Estimated price
- $80–450
Flights from Indianapolis to Roanoke Regional Airport-Woodrum Field via Chicago O'Hare
- Ave. Duration
- 4h 41m
- When
- Every day
- Estimated price
- $95–480
Flights from Indianapolis to Roanoke Regional Airport-Woodrum Field via Philadelphia
- Ave. Duration
- 6h 39m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $110–550
Flights from Indianapolis to Roanoke Regional Airport-Woodrum Field via New York La Guardia
- Ave. Duration
- 8h 15m
- When
- Every day
- Estimated price
- $120–600
Flights from Indianapolis to Washington Dulles International Airport via Charlotte Douglas International Airport
- Ave. Duration
- 4h 11m
- When
- Every day
- Estimated price
- $95–480
Flights from Indianapolis to Tri-Cities Regional Tn/Va Airport via Charlotte Douglas International Airport
- Ave. Duration
- 4h 27m
- When
- Every day
- Estimated price
- $100–550
Flights from Indianapolis to Tri-Cities Regional Tn/Va Airport via Dallas/Ft.Worth
- Ave. Duration
- 5h 43m
- When
- Every day
- Estimated price
- $220–900
Flights from Indianapolis to Tri-Cities Regional Tn/Va Airport via Chicago O'Hare
- Ave. Duration
- 7h 53m
- When
- Every day
- Estimated price
- $110–600
Flights from Indianapolis to Raleigh-Durham International Airport via Charlotte Douglas International Airport
- Ave. Duration
- 3h 33m
- When
- Every day
- Estimated price
- $90–500
Flights from Indianapolis to Ronald Reagan Washington National Airport
- Ave. Duration
- 1h 52m
- When
- Every day
- Estimated price
- $110–650
Flights from Indianapolis to Ronald Reagan Washington National Airport via Charlotte Douglas International Airport
- Ave. Duration
- 4h 33m
- When
- Sunday
- Estimated price
- $140–750
- Website
- delta.com
Flights from Indianapolis to Charlotte Douglas International Airport via Atlanta
- Ave. Duration
- 4h
- When
- Every day
- Estimated price
- $130–700
Flights from Indianapolis to Charlotte Douglas International Airport via Detroit
- Ave. Duration
- 4h 20m
- When
- Every day
- Estimated price
- $140–750
Flights from Indianapolis to Roanoke Regional Airport-Woodrum Field via Atlanta
- Ave. Duration
- 5h
- When
- Every day
- Estimated price
- $100–500
Flights from Indianapolis to Roanoke Regional Airport-Woodrum Field via New York La Guardia
- Ave. Duration
- 7h 10m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $120–600
Flights from Indianapolis to Washington Dulles International Airport via Detroit
- Ave. Duration
- 3h 53m
- When
- Every day
- Estimated price
- $85–450
Flights from Indianapolis to Tri-Cities Regional Tn/Va Airport via Atlanta
- Ave. Duration
- 4h 35m
- When
- Every day
- Estimated price
- $110–600
Flights from Indianapolis to Raleigh-Durham International Airport
- Ave. Duration
- 1h 50m
- When
- Every day
- Estimated price
- $85–480
Flights from Indianapolis to Raleigh-Durham International Airport via Atlanta
- Ave. Duration
- 4h 2m
- When
- Every day
- Estimated price
- $110–600
Flights from Indianapolis to Raleigh-Durham International Airport via Detroit
- Ave. Duration
- 4h 2m
- When
- Every day
- Estimated price
- $110–550
Flights from Indianapolis to Ronald Reagan Washington National Airport via Detroit
- Ave. Duration
- 3h 57m
- When
- Every day
- Estimated price
- $130–700
- Website
- southwest.com
Flights from Indianapolis to Charlotte Douglas International Airport via Nashville
- Ave. Duration
- 3h 51m
- When
- Every day
- Estimated price
- $120–700
Flights from Indianapolis to Charlotte Douglas International Airport via Chicago Midway
- Ave. Duration
- 4h 5m
- When
- Saturday, Tuesday, and Wednesday
- Estimated price
- $140–750
Flights from Indianapolis to Raleigh-Durham International Airport via Nashville
- Ave. Duration
- 3h 40m
- When
- Monday to Wednesday
- Estimated price
- $100–550
Flights from Indianapolis to Raleigh-Durham International Airport via Baltimore
- Ave. Duration
- 3h 48m
- When
- Saturday, Tuesday, and Wednesday
- Estimated price
- $110–600
Flights from Indianapolis to Raleigh-Durham International Airport via Chicago Midway
- Ave. Duration
- 3h 51m
- When
- Saturday, Sunday, Tuesday, and Wednesday
- Estimated price
- $110–600
Flights from Indianapolis to Ronald Reagan Washington National Airport via Chicago Midway
- Ave. Duration
- 4h 20m
- When
- Sunday, Saturday, Tuesday, and Wednesday
- Estimated price
- $150–750
- Website
- united.com
Flights from Indianapolis to Roanoke Regional Airport-Woodrum Field via Washington Dulles International Airport
- Ave. Duration
- 4h 10m
- When
- Every day
- Estimated price
- $90–460
Flights from Indianapolis to Roanoke Regional Airport-Woodrum Field via Chicago O'Hare
- Ave. Duration
- 4h 31m
- When
- Every day
- Estimated price
- $95–480
Flights from Indianapolis to Washington Dulles International Airport
- Ave. Duration
- 1h 44m
- When
- Every day
- Estimated price
- $70–410
Flights from Indianapolis to Washington Dulles International Airport via Toronto
- Ave. Duration
- 4h
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $100–490
Flights from Indianapolis to Tri-Cities Regional Tn/Va Airport via Chicago O'Hare
- Ave. Duration
- 4h 25m
- When
- Every day
- Estimated price
- $110–600
Flights from Indianapolis to Raleigh-Durham International Airport via Washington Dulles International Airport
- Ave. Duration
- 3h 57m
- When
- Every day
- Estimated price
- $100–550
- Website
- allegiantair.com
Flights from Indianapolis to Roanoke Regional Airport-Woodrum Field via St. Petersburg
- Ave. Duration
- 6h 26m
- When
- Thursday and Sunday
- Estimated price
- $160–700
Flights from Indianapolis to Roanoke Regional Airport-Woodrum Field via Orlando Sanford
- Ave. Duration
- 6h 46m
- When
- Friday
- Estimated price
- $150–700
- Website
- aircanada.com
Flights from Indianapolis to Washington Dulles International Airport via Toronto
- Ave. Duration
- 4h
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $100–490
- Website
- aveloair.com
Flights from Indianapolis to Concord
- Ave. Duration
- 1h 27m
- When
- Thursday and Sunday
- Estimated price
- $260–850
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Indianapolis to Ashland Amtrak Station
- Ave. Duration
- 6h 30m
- Frequency
- 3 times a week
- Estimated price
- $85–180
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 888-378-3823
- [email protected]
- Website
- baronsbus.com
Bus from Ashland to Wytheville
- Ave. Duration
- 4h 40m
- Frequency
- Once daily
- Estimated price
- $19–60
- Website
- https://baronsbus.com
Bus from Columbus - Mound St to Wytheville
- Ave. Duration
- 7h 25m
- Frequency
- Once daily
- Estimated price
- $30–75
- Website
- https://baronsbus.com
Bus from Winston Salem(Trans Center) to Wytheville
- Ave. Duration
- 1h 20m
- Frequency
- Once daily
- Estimated price
- $7–40
- Website
- https://baronsbus.com
- Website
- flixbus.com
Bus from Indianapolis to Columbus
- Ave. Duration
- 3h 25m
- Frequency
- Twice daily
- Schedules at
- flixbus.com
- Website
- example.com
Bus from Columbus - Mound St to Wytheville
- Ave. Duration
- 7h 25m
- Frequency
- Once daily
- Schedules at
- example.com
Bus from Columbus to Wytheville
- Ave. Duration
- 7h 45m
- Frequency
- Once daily
- Schedules at
- example.com
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- greyhound.com
Bus from Charlotte Bus Station to Max Meadows
- Ave. Duration
- 2h
- Frequency
- Once daily
- Estimated price
- $21–40
- Website
- https://www.greyhound.com/
Bus from Indianapolis Union Station to Wilson & Ferrell Shell Station - Columbus
- Ave. Duration
- 3h 54m
- Frequency
- 3 times a day
- Estimated price
- $27–55
- Website
- https://www.greyhound.com/
Bus from Charlotte Bus Station to Max Meadows
- Ave. Duration
- 2h
- Frequency
- Once daily
- Estimated price
- $21–40
- Website
- https://www.greyhound.com/
Bus from Durham to Winston Salem(Trans Center)
- Ave. Duration
- 1h 35m
- Frequency
- 3 times a day
- Estimated price
- $12–24
- Website
- https://www.greyhound.com/
- Website
- greyhound.com
Bus from Charlotte Bus Station to Max Meadows
- Ave. Duration
- 2h 5m
- Frequency
- Once daily
- Schedules at
- greyhound.com
Bus from Indianapolis Union Station to Wilson & Ferrell Shell Station - Columbus
- Ave. Duration
- 3h 55m
- Frequency
- 3 times a day
- Schedules at
- greyhound.com
Bus from Charlotte Bus Station to Max Meadows
- Ave. Duration
- 2h 5m
- Frequency
- Once daily
- Schedules at
- greyhound.com
Bus from Durham to Winston Salem(Trans Center)
- Ave. Duration
- 1h 35m
- Frequency
- 3 times a day
- Schedules at
- greyhound.com
- Phone
- +1 540 982 2222
- [email protected]
- Website
- valleymetro.com
Bus from Airport to Exit 118 - Park and Ride
- Ave. Duration
- 40 min
- Frequency
- Every 4 hours
- Estimated price
- $4–5
- Website
- https://www.valleymetro.com
- Phone
- +1-877-462-6342
- [email protected]
- Website
- us.megabus.com
Bus from Route 460 Park and Ride to Rural King Shopping Center
- Ave. Duration
- 1h 5m
- Frequency
- Once daily
- Estimated price
- $12–35
- Website
- https://us.megabus.com
- Adult One-way
- $12–35
Bus from Dulles Airport to Rural King Shopping Center
- Ave. Duration
- 5h 25m
- Frequency
- Once daily
- Estimated price
- $35–65
- Website
- https://us.megabus.com
- Adult One-way
- $35–65
Bus from Park and Ride Lot at I-81 Exit 5 to Rural King Shopping Center
- Ave. Duration
- 1h 10m
- Frequency
- Once daily
- Estimated price
- $15–40
- Website
- https://us.megabus.com
- Adult One-way
- $15–40
Bus from Dulles Airport to Rural King Shopping Center
- Ave. Duration
- 5h 25m
- Frequency
- Once daily
- Estimated price
- $35–65
- Website
- https://us.megabus.com
- Adult One-way
- $35–65
- Phone
- +1-800-827-3490
- [email protected]
- Website
- virginiabreeze.drpt.virginia.gov
Bus from Route 460 Park and Ride to Rural King Shopping Center
- Ave. Duration
- 1h 15m
- Frequency
- Once daily
- Estimated price
- $18–22
- Schedules at
- virginiabreeze.drpt.virginia.gov
Bus from Park and Ride Lot at I-81 Exit 5 to Rural King Shopping Center
- Ave. Duration
- 1h 10m
- Frequency
- Once daily
- Estimated price
- $20–24
- Schedules at
- virginiabreeze.drpt.virginia.gov
- Phone
- +1-423-725-5988
- Website
- blackbearresorttn.com
Shuttle from Black Bear Resort to Low Gap
- Ave. Duration
- 1h
- Frequency
- On demand
- Estimated price
- $72
- Website
- https://blackbearresorttn.com/Shuttle-Service.html
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Why you should take the train in the US
Read the travel guide
Need to know: Greyhound
Read the travel guide
More Questions & Answers
There are 35+ hotels available in Wytheville.













