Rome2Rio

How to get fromInterlaken to Lake Iseoby train, bus, car, or train (Trenitalia)

Find Transport to Lake Iseo

See all options

There are 6 ways to get from Interlaken to Lake Iseo by train, bus, car, or train (Trenitalia)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train, bus

    best
    1. Take the train from Spiez to Domodossolatrain train Ec / ...
    2. Take the bus from Domodossola to Milano Centralebus bus Re4
    3. Take the train from Milano Centrale to Bresciatrain train
    7h 33m

  2. Train

    cheapest
    1. Take the train from Spiez to Domodossolatrain train Ec / ...
    2. Take the train from Domodossola to Rho-Fiera Milanotrain train Re
    3. Take the train from Milano Centrale to Bresciatrain train
    8h 30m
    €47–74

  3. Train, bus via Bergamo

    1. Take the train from Spiez to Domodossolatrain train Ec / ...
    2. Take the bus from Domodossola to Milano Centralebus bus Re4
    3. Take the train from Milano Centrale to Bergamotrain train Re2
    4. Take the bus from Bergamo Autostazione to Castro-Poltragnobus bus C
    8h 17m

  4. Drive  309.8 km

    1. Drive from Interlaken to Iseocar car 309.8 km
    4h 18m
    €65–93

  5. Train, bus via Lucerne

    1. Take the train from Interlaken Ost to Luzerntrain train Lix
    2. Take the train from Luzern to Luganotrain train Ec / ...
    3. Take the train from Lugano to Milano Centraletrain train
    4. Take the train from Milano Centrale to Bergamotrain train Re2
    5. Take the bus from Bergamo Autostazione to Castro-Poltragnobus bus C
    9h 45m
    €119–184

  6. Bus

    1. Take the bus from Interlaken Sonnenhof to Zürich HB Schweizerhofbus bus
    2. Take the bus from Zurich Bus Station to Milanbus bus
    3. Take the bus from Sesto to Bergamobus bus
    4. Take the bus from Bergamo Autostazione to Castro-Poltragnobus bus C
    9h 56m
    €57–81

Comparing Your Travel Options

Map of how to get from Interlaken to Lake Iseo.ExpandLaunch map view
  • Distance: 368.5 km
  • Duration: 7h 33m

What companies run services between Interlaken, Switzerland and Lake Iseo, Italy?

You can take a train from Interlaken West to Sulzano via Spiez, Domodossola, Milano Rogoredo, Milano Centrale, and Brescia in around 8h 30m. Alternatively, you can take a bus from Interlaken Sonnenhof to Castro-Poltragno via Zürich HB Schweizerhof, Zurich Bus Station, Sesto, Bergamo, and Bergamo Autostazione in around 9h 56m.

Train operators
Bus operators

Want to know more about travelling around Italy

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Italy Travel Guides

Read the travel guideItaly Travel Guides

Booking & Getting There