There are 6 ways to get from Interlaken to Mendrisio by train, bus, car, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train via Lucerne
best- Take the train from Interlaken Ost to Luzerntrain Lix / ...
- Take the train from Luzern to Luganotrain Ic21 / ...
4h 51mCHF 78–121Train
cheapest- Take the train from Spiez to Domodossolatrain Ec / ...
- Take the train from Domodossola to Locarno FARTtrain 72 / ...
- Take the train from Locarno to Mendrisiotrain S
5h 49mCHF 32–65Bus
- Take the bus from Interlaken Sonnenhof to Zürich HB Schweizerhofbus Shuttler L1 online shuttle
- Take the bus from ZÜRICH, Carparkplatz am Sihlquai to Comobus
5h 56mCHF 75–107Drive 203.3 km
- Drive from Interlaken to Mendrisiocar 203.3 km
2h 31mCHF 34–49Train, fly
- Take the train from Interlaken West to Zürich Flughafentrain
- Fly from Zurich Airport (ZRH) to Milano Malpensa Airport (MXP)plane ZRH - MXP
- Take the train from Malpensa Aeroporto T1 to Mendrisiotrain
5h 33mCHF 123–281Bus, train
- Take the bus from Meiringen, Bahnhof to Göschenen, Bahnhofbus 162
- Take the train from Göschenen to Cadenazzotrain
- Take the train from Cadenazzo to Mendrisiotrain S
6h 21mCHF 38–70
Interlaken to Mendrisio by train
Comparing Your Travel Options
The cheapest way to get from Interlaken to Mendrisio is to drive which costs SFr 30 - SFr 50 and takes 2h 31m.
The fastest way to get from Interlaken to Mendrisio is to drive which takes 2h 31m and costs SFr 30 - SFr 50.
No, there is no direct bus from Interlaken to Mendrisio. However, there are services departing from Interlaken Sonnenhof and arriving at Mendrisio, Autosilo via ZÜRICH, Carparkplatz am Sihlquai, Como - Chiesa di San Zenone and Chiasso, Stazione. The journey, including transfers, takes approximately 5h 56m.
No, there is no direct train from Interlaken to Mendrisio. However, there are services departing from Interlaken Ost and arriving at Mendrisio via Luzern and Lugano. The journey, including transfers, takes approximately 4h 51m.
The distance between Interlaken and Mendrisio is 250 km. The road distance is 203.3 km.
The best way to get from Interlaken to Mendrisio without a car is to train via Lucerne which takes 4h 51m and costs SFr 75 - SFr 130.
It takes approximately 4h 51m to get from Interlaken to Mendrisio, including transfers.
Interlaken to Mendrisio bus services, operated by Shuttler, depart from Interlaken Sonnenhof station.
Interlaken to Mendrisio train services, operated by Zentralbahn, depart from Interlaken Ost station.
The best way to get from Interlaken to Mendrisio is to train via Lucerne which takes 4h 51m and costs SFr 75 - SFr 130. Alternatively, you can bus, which costs SFr 75 - SFr 110 and takes 5h 56m.
What companies run services between Interlaken, Switzerland and Mendrisio, Switzerland?
You can take a train from Interlaken Ost to Mendrisio via Luzern and Lugano in around 4h 51m. Alternatively, you can take a bus from Interlaken Sonnenhof to Mendrisio, Autosilo via Zürich HB Schweizerhof, ZÜRICH, Carparkplatz am Sihlquai, Como, Como - Chiesa di San Zenone, and Chiasso, Stazione in around 5h 56m.
- Website
- swiss.com
Flights from Zurich Airport to Milano Malpensa Airport
- Ave. Duration
- 55 min
- When
- Every day
- Estimated price
- CHF 65–320
- Website
- ethiopianairlines.com
Flights from Zurich Airport to Milano Malpensa Airport
- Ave. Duration
- 1h 10m
- When
- Every day
- Estimated price
- CHF 90–150
- Phone
- +41 (0)58 668 80 00
- [email protected]
- Website
- Zentralbahn
Train from Interlaken Ost to Luzern
- Ave. Duration
- 1h 51m
- Frequency
- Hourly
- Estimated price
- CHF 30–45
- Website
- Zentralbahn
Train from Luzern to Lugano
- Ave. Duration
- 1h 40m
- Frequency
- Every 3 hours
- Estimated price
- CHF 45–70
- Website
- Swiss Federal Railways (SBB CFF FFS)
Train from Interlaken West to Zürich Flughafen
- Ave. Duration
- 2h 10m
- Frequency
- Every 4 hours
- Estimated price
- CHF 50–80
- Website
- Swiss Federal Railways (SBB CFF FFS)
Train from Malpensa Aeroporto T1 to Mendrisio
- Ave. Duration
- 1h 8m
- Frequency
- Hourly
- Estimated price
- CHF 17–25
- Website
- Swiss Federal Railways (SBB CFF FFS)
Train from Spiez to Domodossola
- Ave. Duration
- 1h 7m
- Frequency
- 3 times a day
- Estimated price
- CHF 29–45
- Website
- Swiss Federal Railways (SBB CFF FFS)
Train from Locarno to Mendrisio
- Ave. Duration
- 56 min
- Frequency
- Hourly
- Estimated price
- CHF 15–22
- Website
- Swiss Federal Railways (SBB CFF FFS)
Train from Cadenazzo to Mendrisio
- Ave. Duration
- 39 min
- Frequency
- Hourly
- Estimated price
- CHF 11–17
- Website
- Swiss Federal Railways (SBB CFF FFS)
- Phone
- +39 02 7249 4494
- [email protected]
- Website
- Trenord
Train from Malpensa Aeroporto T1 to Mendrisio
- Ave. Duration
- 1h 8m
- Frequency
- Hourly
- Estimated price
- CHF 4–6
- Website
- Trenord
Train from Locarno to Mendrisio
- Ave. Duration
- 56 min
- Frequency
- Hourly
- Estimated price
- CHF 4–6
- Website
- Trenord
Train from Cadenazzo to Mendrisio
- Ave. Duration
- 39 min
- Frequency
- Hourly
- Estimated price
- CHF 3–5
- Website
- Trenord
- Phone
- +41 58 327 32 71
- Website
- BLS AG
Train from Spiez to Domodossola
- Ave. Duration
- 1h 41m
- Frequency
- Every 3 hours
- Estimated price
- CHF 16–22
- Website
- BLS AG
- Phone
- +41 (0)91 756 04 00
- [email protected]
- Website
- FART
Train from Domodossola to Locarno FART
- Ave. Duration
- 1h 54m
- Frequency
- Hourly
- Estimated price
- CHF 9–14
- Schedules at
- FART
- Phone
- +41 58 580 70 70
- Website
- Schweizerische Südostbahn AG
Train from Göschenen to Cadenazzo
- Ave. Duration
- 1h 21m
- Frequency
- Hourly
- Estimated price
- CHF 29–45
- Schedules at
- Schweizerische Südostbahn AG
- Phone
- +41 44 552 0807
- [email protected]
- Website
- Shuttler
Bus from Interlaken Sonnenhof to Zürich HB Schweizerhof
- Ave. Duration
- 1h 52m
- Frequency
- 5 times a week
- Estimated price
- CHF 22–26
- Website
- Shuttler
- Phone
- +39 0362 185 0590
- [email protected]
- Website
- Onebus
Bus from ZÜRICH, Carparkplatz am Sihlquai to Como
- Ave. Duration
- 1h 56m
- Frequency
- Once a week
- Estimated price
- CHF 50–75
- Website
- Onebus
- Phone
- +41 (0)848 818 818
- [email protected]
- Website
- PostAuto AG
Bus from Meiringen, Bahnhof to Göschenen, Bahnhof
- Ave. Duration
- 1h 45m
- Frequency
- Once daily
- Estimated price
- CHF 5–8
- Website
- PostAuto AG
Want to know more about travelling around Switzerland
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Booking & Getting There
Interlaken to Mendrisio bus services, operated by Shuttler, arrive at Zürich HB Schweizerhof station.
Interlaken to Mendrisio train services, operated by Zentralbahn, arrive at Luzern station.
Yes, the driving distance between Interlaken to Mendrisio is 203 km. It takes approximately 2h 31m to drive from Interlaken to Mendrisio.
Book your Interlaken to Mendrisio train tickets online with Omio.
There are 5490+ hotels available in Mendrisio.

































