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How to get fromIowa City to Charlestonby bus, plane, train, or car

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There are 9 ways to get from Iowa City to Charleston by bus, plane, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Quad City International Airport, fly

    best
    1. Take the bus from Iowa City to Moline Center Stationbus bus
    2. Fly from Quad City International Airport (MLI) to Charleston International Airport (CHS)plane plane MLI - CHS
    9h 28m
    $97–460

  2. Bus, train

    1. Take the bus from Iowa City to Chicago Bus Stationbus bus
    2. Take the train from Chicago Union Station to Petersburg Amtrak Stationtrain train
    3. Take the train from Petersburg Amtrak Station to Charleston Amtrak Stationtrain train
    34h 33m
    $464–944

  3. Bus, train via Newark

    1. Take the bus from Iowa City to Chicago Bus Stationbus bus
    2. Take the bus from Chicago Bus Station to Newark Penn Stationbus bus
    3. Take the train from Newark Penn Station to Charleston Amtrak Stationtrain train
    38h 54m
    $398–778

  4. Drive 1,048.8 mi

    1. Drive from Iowa City to Charlestoncar car 1,048.8 mi
    18h 52m
    $192–277

  5. Bus to The Eastern Iowa Airport, fly

    1. Take the bus from Court St Transportation Center to GTC Bay 9bus bus
    2. Fly from The Eastern Iowa Airport (CID) to Charleston International Airport (CHS)plane plane CID - CHS
    9h 10m

  6. Bus to Chicago Midway International Airport, fly

    1. Take the bus from Iowa City to Chicago Bus Stationbus bus
    2. Fly from Chicago Midway International Airport (MDW) to Charleston International Airport (CHS)plane plane MDW - CHS
    10h 23m
    $141–624

  7. Bus to Chicago O'Hare International Airport, fly

    1. Take the bus from Iowa City to Chicago Bus Stationbus bus
    2. Fly from Chicago O'Hare International Airport (ORD) to Charleston International Airport (CHS)plane plane ORD - CHS
    10h 44m
    $118–481

  8. Drive to Burlington Municipal Airport, fly

    1. Drive from Iowa City to Burlington Municipal Airport (BRL)car car
    2. Fly from Burlington Municipal Airport (BRL) to Charleston International Airport (CHS)plane plane BRL - CHS
    7h 54m
    $111–483

  9. Bus, train via Wilmington

    1. Take the bus from Iowa City to Chicago Bus Stationbus bus
    2. Take the train from Chicago Union Station to Wilmingtontrain train
    3. Take the train from Wilmington to Charleston Amtrak Stationtrain train
    46h 20m
    $558–1,178

Iowa City to Charleston by bus and train

Calendar14Weekly Services
Duration38h 54mAverage Duration
Ticket$398Cheapest Price
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Questions & Answers

Map of how to get from Iowa City to Charleston.ExpandLaunch map view
  • Distance: 905.4 mi
  • Duration: 9h 28m

What companies run services between Iowa City, IA, USA and Charleston, SC, USA?

There is no direct connection from Iowa City to Charleston. However, you can take the bus to Moline Center Station, walk to Centre Station, take the line 20 bus to QC Airport Shelter, walk to Quad City International Airport (MLI) airport, fly to Charleston International Airport (CHS), walk to Charleston International Airport, then take the line 11 bus to Transit Mall. Alternatively, you can take a bus from Iowa City to Charleston via Chicago Bus Station, Chicago Union Station, Petersburg Amtrak Station, and Charleston Amtrak Station in around 34h 33m.

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