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How to get fromIowa City to Florida Keysby bus, plane, bus (Greyhound, Flixbus), train, shuttle, or car

Find Transport to Florida Keys

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There are 7 ways to get from Iowa City to Florida Keys by bus, plane, bus (Greyhound, Flixbus), train, shuttle, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Quad City International Airport, fly

    best
    1. Take the bus from Iowa City to Moline Center Stationbus bus
    2. Fly from Quad City International Airport (MLI) to Key West International Airport (EYW)plane plane MLI - EYW
    11h 22m
    $174–521

  2. Bus

    1. Take the bus from Iowa City to Chicago Bus Stationbus bus
    2. Take the bus from Chicago Bus Station to Washington Union Stationbus bus
    3. Take the bus from Washington Union Station to Miami Airport Stationbus bus
    4. Take the bus from Miami Airport Station to Big Pine Keybus bus
    2d 2h
    $364–558

  3. Bus, train, shuttle

    1. Take the bus from Iowa City to Chicago Bus Stationbus bus
    2. Take the train from Chicago Union Station to Miami Amtrak Stationtrain train
    3. Take a shuttle bus from Miami, FL - International Airport to Summerland Key - Mote Marine Labshuttle bus
    2d 10h
    $1,316–2,072

  4. Drive  1,581.8 mi

    1. Drive from Iowa City to Florida Keyscar car 1,581.8 mi
    28h 26m
    $289–417

  5. Bus to The Eastern Iowa Airport, fly

    1. Take the bus from Court St Transportation Center to GTC Bay 9bus bus
    2. Fly from The Eastern Iowa Airport (CID) to Key West International Airport (EYW)plane plane CID - EYW
    11h 42m

  6. Bus to Des Moines, fly

    1. Take the bus from Iowa City to Des Moinesbus bus
    2. Fly from Des Moines (DSM) to Key West International Airport (EYW)plane plane DSM - EYW
    12h 39m
    $244–754

  7. Bus to Chicago O'Hare International Airport, fly

    1. Take the bus from Iowa City to Chicago Bus Stationbus bus
    2. Fly from Chicago O'Hare International Airport (ORD) to Key West International Airport (EYW)plane plane ORD - EYW
    13h
    $192–491

Iowa City to Florida Keys by bus and foot

Calendar4Weekly Services
Duration2d 2hAverage Duration
Ticket$364Cheapest Price
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Comparing Your Travel Options

Map of how to get from Iowa City to Florida Keys.ExpandLaunch map view
  • Distance: 1,358.5 mi
  • Duration: 11h 22m

What companies run services between Iowa City, IA, USA and Florida Keys, FL, USA?

You can take a bus from Iowa City to Florida Keys via Chicago Bus Station, Washington Union Station, Miami Airport Station, Big Pine Key, Big Pine Key - CVS / MM30, and Sugarloaf Key - Lower - Sugarloaf Lodge in around 2d 2h.

Airlines
Train operators
Bus operators

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