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How to get fromIowa City to Florida Keysby bus, plane, bus (Greyhound, Flixbus), train, shuttle, or car

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There are 8 ways to get from Iowa City to Florida Keys by bus, plane, bus (Greyhound, Flixbus), train, shuttle, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Quad City International Airport, fly to Key West International Airport

    best
    1. Take the bus from Iowa City to Moline Center Stationbus bus
    2. Fly from Quad City International Airport (MLI) to Key West International Airport (EYW)plane plane MLI - EYW
    10h 48m
    $177–523

  2. Bus

    1. Take the bus from Iowa City to Chicago Bus Stationbus bus
    2. Take the bus from Chicago Bus Station to Washington Union Stationbus bus
    3. Take the bus from Washington Union Station to Miamibus bus
    4. Take the bus from Miami Airport Station to Big Pine Keybus bus
    2d 3h
    $349–635

  3. Bus, train, shuttle

    1. Take the bus from Iowa City to Chicago Bus Stationbus bus
    2. Take the train from Chicago Union Station to Miami Amtrak Stationtrain train
    3. Take a shuttle bus from Miami, FL - International Airport to Summerland Key - Mote Marine Labshuttle bus
    2d 10h
    $861–1,679

  4. Drive 1,581.8 mi

    1. Drive from Iowa City to Florida Keyscar car 1,581.8 mi
    28h 26m
    $289–417

  5. Bus to The Eastern Iowa Airport, fly to Key West International Airport

    1. Take the bus from Court St Transportation Center to GTC Bay 9bus bus
    2. Fly from The Eastern Iowa Airport (CID) to Key West International Airport (EYW)plane plane CID - EYW
    11h 16m

  6. Bus to The Eastern Iowa Airport, fly to Fort Lauderdale–Hollywood International Airport, shuttle

    1. Take the bus from Court St Transportation Center to GTC Bay 9bus bus
    2. Fly from The Eastern Iowa Airport (CID) to Fort Lauderdale–Hollywood International Airport (FLL)plane plane CID - FLL
    3. Take a shuttle bus from Fort Lauderdale, FL - International Airport to Big Pine Key, FLshuttle bus
    12h 24m

  7. Bus to Chicago O'Hare International Airport, fly to Key West International Airport

    1. Take the bus from Iowa City to Chicago Bus Stationbus bus
    2. Fly from Chicago O'Hare International Airport (ORD) to Key West International Airport (EYW)plane plane ORD - EYW
    13h 1m
    $204–565

  8. Drive to Burlington Municipal Airport, fly to Key West International Airport

    1. Drive from Iowa City to Burlington Municipal Airport (BRL)car car
    2. Fly from Burlington Municipal Airport (BRL) to Key West International Airport (EYW)plane plane BRL - EYW
    10h 31m
    $191–555

Iowa City to Florida Keys by bus, taxi, and foot

Calendar4Weekly Services
Duration2d 3hAverage Duration
Ticket$349Cheapest Price
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Questions & Answers

Map of how to get from Iowa City to Florida Keys.ExpandLaunch map view
  • Distance: 1,358.5 mi
  • Duration: 10h 48m

What companies run services between Iowa City, IA, USA and Florida Keys, FL, USA?

You can take a bus from Iowa City to Florida Keys via Chicago Bus Station, Washington Union Station, Miami, Miami Airport Station, Big Pine Key, Big Pine Key - CVS / MM30, and Sugarloaf Key - Lower - Sugarloaf Lodge in around 2d 3h.

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