There are 8 ways to get from Iowa City to Florida Keys by bus, plane, bus (Greyhound, Flixbus), train, shuttle, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus to Quad City International Airport, fly to Key West International Airport
best- Take the bus from Iowa City to Moline Center Stationbus
- Fly from Quad City International Airport (MLI) to Key West International Airport (EYW)plane MLI - EYW
11h 27m$177–511Bus
- Take the bus from Iowa City to Chicago Bus Stationbus
- Take the bus from Chicago Bus Station to Washington Union Stationbus
- Take the bus from Washington Union Station to Miamibus
- Take the bus from Miami Airport Station to Big Pine Keybus
2d 3h$325–575Bus, train, shuttle
- Take the bus from Iowa City to Chicago Bus Stationbus
- Take the train from Chicago Union Station to Miami Amtrak Stationtrain
- Take a shuttle bus from Miami, FL - International Airport to Summerland Key - Mote Marine Lab
2d 10h$809–1,574Drive 1,581.8 mi
- Drive from Iowa City to Florida Keyscar 1,581.8 mi
28h 26m$289–417Bus to The Eastern Iowa Airport, fly to Key West International Airport
- Take the bus from Court St Transportation Center to GTC Bay 9bus
- Fly from The Eastern Iowa Airport (CID) to Key West International Airport (EYW)plane CID - EYW
11h 33mBus to The Eastern Iowa Airport, fly to Fort Lauderdale–Hollywood International Airport, shuttle
- Take the bus from Court St Transportation Center to GTC Bay 9bus
- Fly from The Eastern Iowa Airport (CID) to Fort Lauderdale–Hollywood International Airport (FLL)plane CID - FLL
- Take a shuttle bus from Fort Lauderdale, FL - International Airport to Big Pine Key, FL
12h 24mBus to Chicago O'Hare International Airport, fly to Key West International Airport
- Take the bus from Iowa City to Chicago Bus Stationbus
- Fly from Chicago O'Hare International Airport (ORD) to Key West International Airport (EYW)plane ORD - EYW
13h 1m$192–530Drive to Burlington Municipal Airport, fly to Key West International Airport
- Drive from Iowa City to Burlington Municipal Airport (BRL)car
- Fly from Burlington Municipal Airport (BRL) to Key West International Airport (EYW)plane BRL - EYW
10h 31m$191–545
Iowa City to Florida Keys by bus, taxi, and foot
Questions & Answers
The cheapest way to get from Iowa City to Florida Keys is to bus and fly which costs $170 - $550 and takes 11h 27m.
The fastest way to get from Iowa City to Florida Keys is to drive and fly which takes 10h 31m and costs $190 - $550.
No, there is no direct bus from Iowa City to Florida Keys. However, there are services departing from Iowa City and arriving at Sugarloaf Key - Lower - Sugarloaf Lodge via Chicago Bus Station, Washington Union Station, Miami Airport Station and Big Pine Key - CVS / MM30. The journey, including transfers, takes approximately 2 days 3h.
The distance between Iowa City and Florida Keys is 1366 miles. The road distance is 1591 miles.
The best way to get from Iowa City to Florida Keys without a car is to bus which takes 2 days 3h and costs $320 - $600.
It takes approximately 11h 27m to get from Iowa City to Florida Keys, including transfers.
Iowa City to Florida Keys bus services, operated by Greyhound USA, depart from Iowa City station.
Iowa City to Florida Keys bus services, operated by Greyhound USA, arrive at Chicago Bus Station.
Yes, the driving distance between Iowa City to Florida Keys is 1591 miles. It takes approximately 28h 26m to drive from Iowa City to Florida Keys.
There are 867+ hotels available in Florida Keys.
What companies run services between Iowa City, IA, USA and Florida Keys, FL, USA?
You can take a bus from Iowa City to Florida Keys via Chicago Bus Station, Washington Union Station, Miami, Miami Airport Station, Big Pine Key, Big Pine Key - CVS / MM30, and Sugarloaf Key - Lower - Sugarloaf Lodge in around 2d 3h.
- Website
- aa.com
Flights from Quad City International Airport to Key West International Airport via Charlotte
- Ave. Duration
- 8h 11m
- When
- Every day
- Estimated price
- $95–420
Flights from Quad City International Airport to Key West International Airport via Dallas/Ft.Worth
- Ave. Duration
- 8h 19m
- When
- Every day
- Estimated price
- $110–480
Flights from Quad City International Airport to Key West International Airport via Chicago O'Hare International Airport
- Ave. Duration
- 8h 13m
- When
- Every day
- Estimated price
- $95–420
Flights from The Eastern Iowa Airport to Key West International Airport via Dallas/Ft.Worth
- Ave. Duration
- 8h 32m
- When
- Every day
- Estimated price
- $110–480
Flights from The Eastern Iowa Airport to Key West International Airport via Charlotte
- Ave. Duration
- 8h 37m
- When
- Every day
- Estimated price
- $100–430
Flights from The Eastern Iowa Airport to Key West International Airport via Chicago O'Hare International Airport
- Ave. Duration
- 8h 46m
- When
- Every day
- Estimated price
- $100–430
Flights from The Eastern Iowa Airport to Key West International Airport via Miami
- Ave. Duration
- 10h 31m
- When
- Saturday
- Estimated price
- $95–420
Flights from The Eastern Iowa Airport to Fort Lauderdale–Hollywood International Airport via Charlotte
- Ave. Duration
- 6h 7m
- When
- Every day
- Estimated price
- $120–550
Flights from Chicago O'Hare International Airport to Key West International Airport
- Ave. Duration
- 3h 19m
- When
- Every day
- Estimated price
- $80–370
Flights from Burlington Municipal Airport to Key West International Airport via Chicago O'Hare International Airport
- Ave. Duration
- 6h 8m
- When
- Every day
- Estimated price
- $100–430
- Website
- delta.com
Flights from Quad City International Airport to Key West International Airport via Atlanta
- Ave. Duration
- 5h 19m
- When
- Every day
- Estimated price
- $90–400
Flights from The Eastern Iowa Airport to Key West International Airport via Atlanta
- Ave. Duration
- 5h 26m
- When
- Saturday and Sunday
- Estimated price
- $90–410
Flights from The Eastern Iowa Airport to Fort Lauderdale–Hollywood International Airport via Atlanta
- Ave. Duration
- 5h 52m
- When
- Every day
- Estimated price
- $120–550
Flights from Chicago O'Hare International Airport to Key West International Airport via Atlanta
- Ave. Duration
- 5h 48m
- When
- Every day
- Estimated price
- $80–370
Flights from Burlington Municipal Airport to Key West International Airport via Chicago O'Hare International Airport, Atlanta
- Ave. Duration
- 9h 44m
- When
- Every day
- Estimated price
- $100–430
- Website
- united.com
Flights from Quad City International Airport to Key West International Airport via Chicago O'Hare International Airport
- Ave. Duration
- 5h 59m
- When
- Every day
- Estimated price
- $95–420
Flights from The Eastern Iowa Airport to Key West International Airport via Chicago O'Hare International Airport
- Ave. Duration
- 6h 9m
- When
- Every day
- Estimated price
- $100–430
Flights from The Eastern Iowa Airport to Fort Lauderdale–Hollywood International Airport via Chicago O'Hare International Airport
- Ave. Duration
- 6h 7m
- When
- Every day
- Estimated price
- $120–550
Flights from Chicago O'Hare International Airport to Key West International Airport
- Ave. Duration
- 3h 24m
- When
- Every day
- Estimated price
- $80–370
- Website
- allegiantair.com
Flights from The Eastern Iowa Airport to Fort Lauderdale–Hollywood International Airport
- Ave. Duration
- 3h 8m
- When
- Friday
- Estimated price
- $120–550
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Chicago Union Station to Miami Amtrak Station
- Ave. Duration
- 46h 29m
- Frequency
- Once daily
- Estimated price
- $600–1,300
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Iowa City to Moline Center Station
- Ave. Duration
- 1h 25m
- Frequency
- Once daily
- Estimated price
- $8–17
- Website
- Greyhound
Bus from Iowa City to Chicago Bus Station
- Ave. Duration
- 4h 45m
- Frequency
- Twice daily
- Estimated price
- $30–65
- Website
- Greyhound
Bus from Chicago Bus Station to Washington Union Station
- Ave. Duration
- 16h 35m
- Frequency
- Twice daily
- Estimated price
- $100–200
- Website
- Greyhound
Bus from Miami Airport Station to Big Pine Key
- Ave. Duration
- 3h 40m
- Frequency
- 3 times a day
- Estimated price
- $18–35
- Website
- Greyhound
Bus from Iowa City to Chicago Bus Station
- Ave. Duration
- 4h 45m
- Frequency
- Twice daily
- Estimated price
- $30–65
- Website
- Greyhound
Bus from Iowa City to Chicago Bus Station
- Ave. Duration
- 4h 45m
- Frequency
- Twice daily
- Estimated price
- $30–65
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from Washington Union Station to Miami
- Ave. Duration
- 22h 5m
- Frequency
- 4 times a week
- Estimated price
- $160–260
- Schedules at
- Flixbus USA
- Phone
- +1 (305) 289-9997
- [email protected]
- Website
- Keys Shuttle
Shuttle from Miami, FL - International Airport to Summerland Key - Mote Marine Lab
- Ave. Duration
- 3h 30m
- Frequency
- 3 times a day
- Estimated price
- $150–180
- Website
- Keys Shuttle
Shuttle from Fort Lauderdale, FL - International Airport to Big Pine Key, FL
- Ave. Duration
- 3h 30m
- Frequency
- 3 times a day
- Estimated price
- $170–200
- Website
- Keys Shuttle
- Phone
- +1-319-362-0375
- Website
- 380 Express Corridor Rides
Bus from Court St Transportation Center to GTC Bay 9
- Ave. Duration
- 51 min
- Frequency
- Hourly
- Website
- 380 Express Corridor Rides
- Schedules at
- 380 Express Schedule
Bus from Court St Transportation Center to GTC Bay 9
- Ave. Duration
- 51 min
- Frequency
- Hourly
- Website
- 380 Express Corridor Rides
- Schedules at
- 380 Express Schedule
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide
Why you should take the train in the US
Read the travel guide







