There are 9 ways to get from Iowa City to Jeffersonville by bus (Greyhound, Amtrak), car, bus, plane, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus
best- Take the bus from Iowa City to Chicago Bus Stationbus Greyhound US0123S / ...
- Take the bus from Chicago Union Station to Louisville, KYbus Chicago
13h 47m$85–128Drive 468.6 mi
- Drive from Iowa City to Jeffersonvillecar 468.6 mi
7h 54m$86–124Bus to The Eastern Iowa Airport, fly to Blue Grass Airport, drive
- Take the bus from Court St Transportation Center to GTC Bay 9bus
- Fly from The Eastern Iowa Airport (CID) to Blue Grass Airport (LEX)plane CID - LEX
- Drive from Lexington-Airport-LEX to Jeffersonvillecar
8h 52mBus, train
- Take the bus from Iowa City to Chicago Bus Stationbus
- Take the train from Chicago Union Station to Indianapolistrain
- Take the bus from Indianapolis Union Station to Louisville, KYbus
15h 6m$117–243Bus to Quad City International Airport, fly to Louisville International Airport
- Take the bus from Iowa City to Moline Center Stationbus
- Fly from Quad City International Airport (MLI) to Louisville International Airport (SDF)plane MLI - SDF
9h 38m$92–504Bus to The Eastern Iowa Airport, fly to Louisville International Airport
- Take the bus from Court St Transportation Center to GTC Bay 9bus
- Fly from The Eastern Iowa Airport (CID) to Louisville International Airport (SDF)plane CID - SDF
9h 20mBus to Chicago Midway International Airport, fly to Louisville International Airport
- Take the bus from Iowa City to Chicago Bus Stationbus
- Fly from Chicago Midway International Airport (MDW) to Louisville International Airport (SDF)plane MDW - SDF
10h 17m$121–629Bus to Chicago O'Hare International Airport, fly to Louisville International Airport
- Take the bus from Iowa City to Chicago Bus Stationbus
- Fly from Chicago O'Hare International Airport (ORD) to Louisville International Airport (SDF)plane ORD - SDF
10h 44m$103–496Drive to Burlington Municipal Airport, fly to Louisville International Airport
- Drive from Iowa City to Burlington Municipal Airport (BRL)car
- Fly from Burlington Municipal Airport (BRL) to Louisville International Airport (SDF)plane BRL - SDF
8h 34m$101–517
Iowa City to Jeffersonville by bus and foot
Questions & Answers
The cheapest way to get from Iowa City to Jeffersonville is to bus which costs $85 - $130 and takes 13h 47m.
The fastest way to get from Iowa City to Jeffersonville is to drive which takes 7h 54m and costs $85 - $130.
No, there is no direct bus from Iowa City to Jeffersonville. However, there are services departing from Iowa City and arriving at Court @ Spring via Chicago Union Station and Liberty @ Roy Wilkins. The journey, including transfers, takes approximately 13h 47m.
The distance between Iowa City and Jeffersonville is 526 miles. The road distance is 471.4 miles.
The best way to get from Iowa City to Jeffersonville without a car is to bus which takes 13h 47m and costs $85 - $130.
It takes approximately 13h 47m to get from Iowa City to Jeffersonville, including transfers.
Iowa City to Jeffersonville bus services, operated by Greyhound USA, depart from Iowa City station.
Iowa City to Jeffersonville bus services, operated by Greyhound USA, arrive at Chicago Bus Station.
Jeffersonville is 1h ahead of Iowa City. It is currently 5:19 PM in Iowa City and 6:19 PM in Jeffersonville.
Yes, the driving distance between Iowa City to Jeffersonville is 471 miles. It takes approximately 7h 54m to drive from Iowa City to Jeffersonville.
What companies run services between Iowa City, IA, USA and Jeffersonville, IN, USA?
You can take a bus from Iowa City to Court @ Spring via Chicago Bus Station, Chicago Union Station, Louisville, KY, and Liberty @ Roy Wilkins in around 13h 47m.
- Website
- aa.com
Flights from The Eastern Iowa Airport to Blue Grass Airport via Chicago O'Hare International Airport
- Ave. Duration
- 6h 49m
- When
- Every day
- Estimated price
- $260–1,500
Flights from The Eastern Iowa Airport to Blue Grass Airport via Charlotte
- Ave. Duration
- 5h 21m
- When
- Sunday
- Estimated price
- $400–1,900
Flights from The Eastern Iowa Airport to Blue Grass Airport via Dallas/Ft.Worth
- Ave. Duration
- 7h 22m
- When
- Every day
- Estimated price
- $500–2,300
Flights from Quad City International Airport to Louisville International Airport via Chicago O'Hare International Airport
- Ave. Duration
- 5h 17m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $80–480
Flights from Quad City International Airport to Louisville International Airport via Dallas/Ft.Worth
- Ave. Duration
- 6h 21m
- When
- Every day
- Estimated price
- $180–800
Flights from Quad City International Airport to Louisville International Airport via Charlotte
- Ave. Duration
- 6h 5m
- When
- Every day
- Estimated price
- $140–650
Flights from The Eastern Iowa Airport to Louisville International Airport via Chicago O'Hare International Airport
- Ave. Duration
- 4h 30m
- When
- Every day
- Estimated price
- $170–1,000
Flights from The Eastern Iowa Airport to Louisville International Airport via Dallas/Ft.Worth
- Ave. Duration
- 6h 19m
- When
- Every day
- Estimated price
- $350–1,600
Flights from The Eastern Iowa Airport to Louisville International Airport via Charlotte
- Ave. Duration
- 6h 30m
- When
- Monday to Saturday
- Estimated price
- $280–1,400
Flights from Chicago O'Hare International Airport to Louisville International Airport
- Ave. Duration
- 1h 34m
- When
- Every day
- Estimated price
- $65–420
Flights from Burlington Municipal Airport to Louisville International Airport via Chicago O'Hare International Airport
- Ave. Duration
- 4h 40m
- When
- Monday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $85–490
- Website
- united.com
Flights from The Eastern Iowa Airport to Blue Grass Airport via Chicago O'Hare International Airport
- Ave. Duration
- 4h 38m
- When
- Every day
- Estimated price
- $260–1,500
Flights from Quad City International Airport to Louisville International Airport via Chicago O'Hare International Airport
- Ave. Duration
- 4h 22m
- When
- Every day
- Estimated price
- $80–480
Flights from The Eastern Iowa Airport to Louisville International Airport via Chicago O'Hare International Airport
- Ave. Duration
- 4h 19m
- When
- Every day
- Estimated price
- $170–1,000
Flights from Chicago O'Hare International Airport to Louisville International Airport
- Ave. Duration
- 1h 37m
- When
- Every day
- Estimated price
- $65–420
Flights from Burlington Municipal Airport to Louisville International Airport via Chicago O'Hare International Airport
- Ave. Duration
- 6h 26m
- When
- Sunday
- Estimated price
- $85–490
- Website
- delta.com
Flights from The Eastern Iowa Airport to Blue Grass Airport via Atlanta
- Ave. Duration
- 5h 11m
- When
- Every day
- Estimated price
- $390–1,900
Flights from The Eastern Iowa Airport to Blue Grass Airport via Minneapolis
- Ave. Duration
- 5h 39m
- When
- Saturday
- Estimated price
- $360–1,800
Flights from Quad City International Airport to Louisville International Airport via Atlanta
- Ave. Duration
- 5h 24m
- When
- Every day
- Estimated price
- $130–650
Flights from The Eastern Iowa Airport to Louisville International Airport via Atlanta
- Ave. Duration
- 5h 21m
- When
- Every day
- Estimated price
- $270–1,300
Flights from The Eastern Iowa Airport to Louisville International Airport via Minneapolis
- Ave. Duration
- 6h 32m
- When
- Every day
- Estimated price
- $230–1,200
- Website
- southwest.com
Flights from Chicago Midway International Airport to Louisville International Airport
- Ave. Duration
- 1h 16m
- When
- Every day
- Estimated price
- $80–550
Flights from Chicago Midway International Airport to Louisville International Airport via Nashville
- Ave. Duration
- 3h 15m
- When
- Sunday
- Estimated price
- $110–650
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Chicago Union Station to Indianapolis
- Ave. Duration
- 4h 54m
- Frequency
- 3 times a week
- Estimated price
- $60–130
- Website
- https://www.amtrak.com/home.html
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- greyhound.com
Bus from Iowa City to Chicago Bus Station
- Ave. Duration
- 4h 45m
- Frequency
- Twice daily
- Estimated price
- $30–65
- Website
- https://www.greyhound.com/
Bus from Iowa City to Chicago Bus Station
- Ave. Duration
- 4h 45m
- Frequency
- Twice daily
- Estimated price
- $30–65
- Website
- https://www.greyhound.com/
Bus from Iowa City to Moline Center Station
- Ave. Duration
- 1h 25m
- Frequency
- Once daily
- Estimated price
- $9–18
- Website
- https://www.greyhound.com/
Bus from Iowa City to Chicago Bus Station
- Ave. Duration
- 4h 45m
- Frequency
- Twice daily
- Estimated price
- $30–65
- Website
- https://www.greyhound.com/
Bus from Iowa City to Chicago Bus Station
- Ave. Duration
- 4h 45m
- Frequency
- Twice daily
- Estimated price
- $30–65
- Website
- https://www.greyhound.com/
Rome2Rio's guide to Amtrak Thruway
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Bus from Chicago Union Station to Louisville, KY
- Ave. Duration
- 7h
- Frequency
- Twice daily
- Estimated price
- $50–60
- Website
- https://www.amtrak.com/home.html
- Adult
- $50–60
Bus from Indianapolis Union Station to Louisville, KY
- Ave. Duration
- 2h 25m
- Frequency
- Twice daily
- Estimated price
- $22–45
- Website
- https://www.amtrak.com/home.html
- Adult
- $22–45
- Phone
- +1-319-362-0375
- Website
- 380express.com
Bus from Court St Transportation Center to GTC Bay 9
- Ave. Duration
- 51 min
- Frequency
- Hourly
- Website
- https://www.380express.com
- Schedules at
- https://www.380express.com/schedule/
Bus from Court St Transportation Center to GTC Bay 9
- Ave. Duration
- 51 min
- Frequency
- Hourly
- Website
- https://www.380express.com
- Schedules at
- https://www.380express.com/schedule/
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide
Why you should take the train in the US
Read the travel guide
More Questions & Answers
There are 605+ hotels available in Jeffersonville.






