Rome2Rio

How to get fromIowa City to La Crosseby bus, train, bus (Greyhound), car, or plane

Find Transport to La Crosse

See all options

There are 6 ways to get from Iowa City to La Crosse by bus, train, bus (Greyhound), car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus, train

    best
    1. Take the bus from Iowa City to Chicago Bus Stationbus bus Greyhound US0123S / ...
    2. Take the train from Chicago Union Station to La Crosse Amtrak Stationtrain train Empire Builder / ...
    10h 53m
    $124–255

  2. Drive 176.3 mi

    cheapest
    1. Drive from Iowa City to La Crossecar car 176.3 mi
    3h 43m
    $33–47

  3. Bus

    1. Take the bus from Iowa City to Des Moinesbus bus
    2. Take the bus from Des Moines to St. Paulbus bus
    3. Take the bus from St. Paul to La Crossebus bus
    12h
    $92–172

  4. Bus to The Eastern Iowa Airport, fly

    1. Take the bus from Court St Transportation Center to GTC Bay 9bus bus
    2. Fly from The Eastern Iowa Airport (CID) to La Crosse (LSE)plane plane CID - LSE
    8h 46m

  5. Bus via Chicago

    1. Take the bus from Iowa City to Chicago Bus Stationbus bus
    2. Take the bus from W Jackson Blvd, after S Clinton St to 250 N. Lake St - Madison UW Campusbus bus
    3. Take the bus from Madison to La Crossebus bus
    12h 50m
    $94–175

  6. Bus to Quad City International Airport, fly

    1. Take the bus from Iowa City to Moline Center Stationbus bus
    2. Fly from Quad City International Airport (MLI) to La Crosse (LSE)plane plane MLI - LSE
    7h 52m
    $79–361

Iowa City to La Crosse by bus, foot, and train

Calendar14Weekly Services
Duration10h 53mAverage Duration
Ticket$124Cheapest Price
See schedules

Questions & Answers

Map of how to get from Iowa City to La Crosse.ExpandLaunch map view
  • Distance: 503.3 mi
  • Duration: 10h 53m

What companies run services between Iowa City, IA, USA and La Crosse, WI, USA?

You can take a bus from Iowa City to La Crosse via Des Moines and St. Paul in around 12h.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers