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How to get fromIowa City to Louisvilleby bus (Greyhound, Flixbus), car, bus, plane, or train

Find Transport to Louisville

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There are 9 ways to get from Iowa City to Louisville by bus (Greyhound, Flixbus), car, bus, plane, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from Iowa City to Chicago Bus Stationbus bus Greyhound US0123S / ...
    2. Take the bus from Chicago Bus Station to Louisville Bus Stationbus bus Greyhound US0100
    11h 50m
    $81–130

  2. Drive  469.9 mi

    1. Drive from Iowa City to Louisvillecar car 469.9 mi
    7h 56m
    $86–124

  3. Bus to Quad City International Airport, fly to Louisville International Airport

    1. Take the bus from Iowa City to Moline Center Stationbus bus
    2. Fly from Quad City International Airport (MLI) to Louisville International Airport (SDF)plane plane MLI - SDF
    8h 25m
    $106–619

  4. Bus, train

    1. Take the bus from Iowa City to Chicago Bus Stationbus bus
    2. Take the train from Chicago Union Station to Indianapolistrain train
    3. Take the bus from Indianapolis Union Station to Louisville Bus Stationbus bus
    13h 38m
    $103–220

  5. Bus via Bloomington

    1. Take the bus from Iowa City to Chicago Bus Stationbus bus
    2. Take the bus from Chicago Bus Station to Bloomingtonbus bus
    3. Take the bus from Bloomington to Louisville Bus Stationbus bus
    13h 55m
    $84–131

  6. Bus to The Eastern Iowa Airport, fly to Louisville International Airport

    1. Take the bus from Court St Transportation Center to GTC Bay 9bus bus
    2. Fly from The Eastern Iowa Airport (CID) to Louisville International Airport (SDF)plane plane CID - SDF
    8h 40m

  7. Bus to The Eastern Iowa Airport, fly to Blue Grass Airport, drive

    1. Take the bus from Court St Transportation Center to GTC Bay 9bus bus
    2. Fly from The Eastern Iowa Airport (CID) to Blue Grass Airport (LEX)plane plane CID - LEX
    3. Drive from Lexington-Airport-LEX to Louisvillecar car
    8h 44m

  8. Bus to Chicago O'Hare International Airport, fly to Louisville International Airport

    1. Take the bus from Iowa City to Chicago Bus Stationbus bus
    2. Fly from Chicago O'Hare International Airport (ORD) to Louisville International Airport (SDF)plane plane ORD - SDF
    9h 23m
    $112–526

  9. Bus to Chicago Midway International Airport, fly to Louisville International Airport

    1. Take the bus from Iowa City to Chicago Bus Stationbus bus
    2. Fly from Chicago Midway International Airport (MDW) to Louisville International Airport (SDF)plane plane MDW - SDF
    9h 11m
    $134–713

Iowa City to Louisville by bus

Calendar14Weekly Buses
Duration11h 50mAverage Duration
Ticket$81Cheapest Price
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Comparing Your Travel Options

Map of how to get from Iowa City to Louisville.ExpandLaunch map view
  • Distance: 521.3 mi
  • Duration: 11h 50m

What companies run services between Iowa City, IA, USA and Louisville, KY, USA?

You can take a bus from Iowa City to Louisville Bus Station via Chicago Bus Station in around 11h 50m.

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