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How to get fromIowa City to Louisvilleby bus (Greyhound, Amtrak), car, bus, plane, or train

Find Transport to Louisville

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There are 9 ways to get from Iowa City to Louisville by bus (Greyhound, Amtrak), car, bus, plane, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from Iowa City to Chicago Bus Stationbus bus Greyhound US0123S / ...
    2. Take the bus from Chicago Union Station to Louisville, KYbus bus Chicago
    12h 39m
    $86–116

  2. Drive  469.9 mi

    1. Drive from Iowa City to Louisvillecar car 469.9 mi
    7h 56m
    $86–124

  3. Bus to Quad City International Airport, fly to Louisville International Airport

    1. Take the bus from Iowa City to Moline Center Stationbus bus
    2. Fly from Quad City International Airport (MLI) to Louisville International Airport (SDF)plane plane MLI - SDF
    8h 25m
    $107–619

  4. Bus, train

    1. Take the bus from Iowa City to Chicago Bus Stationbus bus
    2. Take the train from Chicago Union Station to Indianapolistrain train
    3. Take the bus from Indianapolis Union Station to Louisville, KYbus bus
    13h 43m
    $158–271

  5. Bus to The Eastern Iowa Airport, fly to Louisville International Airport

    1. Take the bus from Court St Transportation Center to GTC Bay 9bus bus
    2. Fly from The Eastern Iowa Airport (CID) to Louisville International Airport (SDF)plane plane CID - SDF
    8h 40m

  6. Bus to The Eastern Iowa Airport, fly to Blue Grass Airport, drive

    1. Take the bus from Court St Transportation Center to GTC Bay 9bus bus
    2. Fly from The Eastern Iowa Airport (CID) to Blue Grass Airport (LEX)plane plane CID - LEX
    3. Drive from Lexington-Airport-LEX to Louisvillecar car
    8h 44m

  7. Bus to Chicago O'Hare International Airport, fly to Louisville International Airport

    1. Take the bus from Iowa City to Chicago Bus Stationbus bus
    2. Fly from Chicago O'Hare International Airport (ORD) to Louisville International Airport (SDF)plane plane ORD - SDF
    9h 29m
    $112–527

  8. Bus to Chicago Midway International Airport, fly to Louisville International Airport

    1. Take the bus from Iowa City to Chicago Bus Stationbus bus
    2. Fly from Chicago Midway International Airport (MDW) to Louisville International Airport (SDF)plane plane MDW - SDF
    9h 11m
    $134–714

  9. Drive to Burlington Municipal Airport, fly to Louisville International Airport

    1. Drive from Iowa City to Burlington Municipal Airport (BRL)car car
    2. Fly from Burlington Municipal Airport (BRL) to Louisville International Airport (SDF)plane plane BRL - SDF
    7h 33m
    $115–624

Iowa City to Louisville by bus and foot

Calendar14Weekly Services
Duration12h 39mAverage Duration
Ticket$86Cheapest Price
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Comparing Your Travel Options

Map of how to get from Iowa City to Louisville.ExpandLaunch map view
  • Distance: 522.4 mi
  • Duration: 12h 39m

What companies run services between Iowa City, IA, USA and Louisville, KY, USA?

You can take a bus from Iowa City to Louisville, KY via Chicago Bus Station and Chicago Union Station in around 12h 39m.

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