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How to get fromIowa City to Mississippiby bus, plane, bus (Greyhound, Flixbus), train, or car

Find Transport to Mississippi

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There are 8 ways to get from Iowa City to Mississippi by bus, plane, bus (Greyhound, Flixbus), train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Quad City International Airport, fly to Memphis

    best
    1. Take the bus from Iowa City to Moline Center Stationbus bus
    2. Fly from Quad City International Airport (MLI) to Memphis (MEM)plane plane MLI - MEM
    7h 41m
    $163–793

  2. Drive  732.6 mi

    cheapest
    1. Drive from Iowa City to Jacksoncar car 732.6 mi
    12h 19m
    $134–194

  3. Bus

    1. Take the bus from Iowa City to Chicago Bus Stationbus bus
    2. Take the bus from Chicago Bus Station to Memphis Bus Stationbus bus
    3. Take the bus from Memphis Bus Station to Jacksonbus bus
    20h 15m
    $146–251

  4. Bus, train

    1. Take the bus from Iowa City to Chicago Bus Stationbus bus Greyhound US0123S / ...
    2. Take the train from Chicago Union Station to Jacksontrain train City of New Orleans
    21h 29m
    $236–606

  5. Bus to The Eastern Iowa Airport, fly to Memphis

    1. Take the bus from Court St Transportation Center to GTC Bay 9bus bus
    2. Fly from The Eastern Iowa Airport (CID) to Memphis (MEM)plane plane CID - MEM
    7h 40m

  6. Bus to The Eastern Iowa Airport, fly to Gulfport-Biloxi Regional Airport

    1. Take the bus from Court St Transportation Center to GTC Bay 9bus bus
    2. Fly from The Eastern Iowa Airport (CID) to Gulfport-Biloxi Regional Airport (GPT)plane plane CID - GPT
    8h 34m

  7. Bus to The Eastern Iowa Airport, fly to Jackson/Vicksburg

    1. Take the bus from Court St Transportation Center to GTC Bay 9bus bus
    2. Fly from The Eastern Iowa Airport (CID) to Jackson/Vicksburg (JAN)plane plane CID - JAN
    8h 3m

  8. Bus to Chicago O'Hare International Airport, fly to Memphis

    1. Take the bus from Iowa City to Chicago Bus Stationbus bus
    2. Fly from Chicago O'Hare International Airport (ORD) to Memphis (MEM)plane plane ORD - MEM
    8h 54m
    $163–691

Iowa City to Mississippi by bus

Calendar7Weekly Buses
Duration20h 15mAverage Duration
Ticket$146Cheapest Price
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Comparing Your Travel Options

Map of how to get from Iowa City to Mississippi.ExpandLaunch map view
  • Distance: 516.9 mi
  • Duration: 7h 41m

What companies run services between Iowa City, IA, USA and Mississippi, USA?

You can take a bus from Iowa City to Jackson via Chicago Bus Station and Memphis Bus Station in around 20h 15m.

Airlines
Train operators
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